U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Schizophrenia 11(SCZD11)

MedGen UID:
334205
Concept ID:
C1842605
Disease or Syndrome
Synonyms: SCHIZOPHRENIA SUSCEPTIBILITY LOCUS, CHROMOSOME 10q-RELATED; SCZD11
 
Monarch Initiative: MONDO:0011960
OMIM®: 608078

Definition

A schizophrenia that has material basis in a mutation on chromosome 10q22.3. [from MONDO]

Professional guidelines

PubMed

Valle R
Rev Colomb Psiquiatr (Engl Ed) 2022 Jan-Mar;51(1):61-70. Epub 2022 Feb 21 doi: 10.1016/j.rcpeng.2020.09.003. PMID: 35210207
Noto C, Ota VK, Santoro ML, Gouvea ES, Silva PN, Spindola LM, Cordeiro Q, Bressan RA, Gadelha A, Brietzke E, Belangero SI, Maes M
Mol Neurobiol 2016 Oct;53(8):5701-9. Epub 2015 Oct 22 doi: 10.1007/s12035-015-9489-3. PMID: 26491028

Recent clinical studies

Etiology

Mulligan LD, Bojanić L, Hunt IM, Baird A, Turnbull P, Kapur N, Appleby L, Shaw J
Schizophr Res 2024 May;267:254-260. Epub 2024 Apr 5 doi: 10.1016/j.schres.2024.03.048. PMID: 38581828
van den Heuvel LL, Smit AM, Stalder T, Kirschbaum C, Seedat S, Emsley R
Early Interv Psychiatry 2022 Aug;16(8):902-911. Epub 2022 Jan 3 doi: 10.1111/eip.13238. PMID: 34978366
Pardiñas AF, Holmans P, Pocklington AJ, Escott-Price V, Ripke S, Carrera N, Legge SE, Bishop S, Cameron D, Hamshere ML, Han J, Hubbard L, Lynham A, Mantripragada K, Rees E, MacCabe JH, McCarroll SA, Baune BT, Breen G, Byrne EM, Dannlowski U, Eley TC, Hayward C, Martin NG, McIntosh AM, Plomin R, Porteous DJ, Wray NR, Caballero A, Geschwind DH, Huckins LM, Ruderfer DM, Santiago E, Sklar P, Stahl EA, Won H, Agerbo E, Als TD, Andreassen OA, Bækvad-Hansen M, Mortensen PB, Pedersen CB, Børglum AD, Bybjerg-Grauholm J, Djurovic S, Durmishi N, Pedersen MG, Golimbet V, Grove J, Hougaard DM, Mattheisen M, Molden E, Mors O, Nordentoft M, Pejovic-Milovancevic M, Sigurdsson E, Silagadze T, Hansen CS, Stefansson K, Stefansson H, Steinberg S, Tosato S, Werge T; GERAD1 Consortium; CRESTAR Consortium, Collier DA, Rujescu D, Kirov G, Owen MJ, O'Donovan MC, Walters JTR
Nat Genet 2018 Mar;50(3):381-389. Epub 2018 Feb 26 doi: 10.1038/s41588-018-0059-2. PMID: 29483656Free PMC Article
Goes FS, Pirooznia M, Parla JS, Kramer M, Ghiban E, Mavruk S, Chen YC, Monson ET, Willour VL, Karchin R, Flickinger M, Locke AE, Levy SE, Scott LJ, Boehnke M, Stahl E, Moran JL, Hultman CM, Landén M, Purcell SM, Sklar P, Zandi PP, McCombie WR, Potash JB
JAMA Psychiatry 2016 Jun 1;73(6):590-7. doi: 10.1001/jamapsychiatry.2016.0251. PMID: 27120077Free PMC Article
Williams NM, Preece A, Spurlock G, Norton N, Williams HJ, Zammit S, O'Donovan MC, Owen MJ
Mol Psychiatry 2003 May;8(5):485-7. doi: 10.1038/sj.mp.4001348. PMID: 12808428

Diagnosis

Tasdemir I, Cesur E, Mengus A, Asliyüksek H, Karamustafalioglu KO
Int J Law Psychiatry 2023 May-Jun;88:101888. Epub 2023 Apr 26 doi: 10.1016/j.ijlp.2023.101888. PMID: 37116429
Pescosolido BA, Halpern-Manners A, Luo L, Perry B
JAMA Netw Open 2021 Dec 1;4(12):e2140202. doi: 10.1001/jamanetworkopen.2021.40202. PMID: 34932103Free PMC Article
Goes FS, Pirooznia M, Parla JS, Kramer M, Ghiban E, Mavruk S, Chen YC, Monson ET, Willour VL, Karchin R, Flickinger M, Locke AE, Levy SE, Scott LJ, Boehnke M, Stahl E, Moran JL, Hultman CM, Landén M, Purcell SM, Sklar P, Zandi PP, McCombie WR, Potash JB
JAMA Psychiatry 2016 Jun 1;73(6):590-7. doi: 10.1001/jamapsychiatry.2016.0251. PMID: 27120077Free PMC Article
Salvatore P, Bhuvaneswar C, Tohen M, Khalsa HM, Maggini C, Baldessarini RJ
Psychopathology 2014;47(4):261-9. Epub 2014 Feb 7 doi: 10.1159/000357813. PMID: 24516070Free PMC Article
Nicolson R, Brookner FB, Lenane M, Gochman P, Ingraham LJ, Egan MF, Kendler KS, Pickar D, Weinberger DR, Rapoport JL
Am J Psychiatry 2003 Mar;160(3):490-5. doi: 10.1176/appi.ajp.160.3.490. PMID: 12611830

Therapy

Forbes A, Hobart M, Ouyang J, Shi L, Pfister S, Hakala M
Int J Neuropsychopharmacol 2018 May 1;21(5):433-441. doi: 10.1093/ijnp/pyy002. PMID: 29415258Free PMC Article
Dunn AG, Mandl KD, Coiera E, Bourgeois FT
PLoS One 2013;8(12):e84951. Epub 2013 Dec 23 doi: 10.1371/journal.pone.0084951. PMID: 24376857Free PMC Article
Kivircik BB, Alptekin K, Calişkan S, Cömlekçi A, Orük G, Tümüklü M, Kürklü K, Arkar H, Türk A, Calişkan M, Yeşil S
Prog Neuropsychopharmacol Biol Psychiatry 2003 Aug;27(5):795-9. doi: 10.1016/S0278-5846(03)00111-8. PMID: 12921912
Tsai G, Goff DC, Chang RW, Flood J, Baer L, Coyle JT
Am J Psychiatry 1998 Sep;155(9):1207-13. doi: 10.1176/ajp.155.9.1207. PMID: 9734544
Wilkinson G, Piccinelli M, Falloon I, Krekorian H, McLees S
Br J Psychiatry 1995 Jul;167(1):26-37; discussion 38-40. doi: 10.1192/bjp.167.1.26. PMID: 7551605

Prognosis

Goes FS, Pirooznia M, Parla JS, Kramer M, Ghiban E, Mavruk S, Chen YC, Monson ET, Willour VL, Karchin R, Flickinger M, Locke AE, Levy SE, Scott LJ, Boehnke M, Stahl E, Moran JL, Hultman CM, Landén M, Purcell SM, Sklar P, Zandi PP, McCombie WR, Potash JB
JAMA Psychiatry 2016 Jun 1;73(6):590-7. doi: 10.1001/jamapsychiatry.2016.0251. PMID: 27120077Free PMC Article
Hjorthøj C, Østergaard ML, Benros ME, Toftdahl NG, Erlangsen A, Andersen JT, Nordentoft M
Lancet Psychiatry 2015 Sep;2(9):801-8. Epub 2015 Aug 12 doi: 10.1016/S2215-0366(15)00207-2. PMID: 26277044
Killgore WD, Rosso IM, Gruber SA, Yurgelun-Todd DA
Cogn Behav Neurol 2009 Mar;22(1):28-37. doi: 10.1097/WNN.0b013e318192cc67. PMID: 19372768
Schneid-Kofman N, Sheiner E, Levy A
Int J Gynaecol Obstet 2008 Apr;101(1):53-6. Epub 2007 Dec 20 doi: 10.1016/j.ijgo.2007.10.007. PMID: 18082746
Tsai G, Goff DC, Chang RW, Flood J, Baer L, Coyle JT
Am J Psychiatry 1998 Sep;155(9):1207-13. doi: 10.1176/ajp.155.9.1207. PMID: 9734544

Clinical prediction guides

Mulligan LD, Bojanić L, Hunt IM, Baird A, Turnbull P, Kapur N, Appleby L, Shaw J
Schizophr Res 2024 May;267:254-260. Epub 2024 Apr 5 doi: 10.1016/j.schres.2024.03.048. PMID: 38581828
Tasdemir I, Cesur E, Mengus A, Asliyüksek H, Karamustafalioglu KO
Int J Law Psychiatry 2023 May-Jun;88:101888. Epub 2023 Apr 26 doi: 10.1016/j.ijlp.2023.101888. PMID: 37116429
van den Heuvel LL, Smit AM, Stalder T, Kirschbaum C, Seedat S, Emsley R
Early Interv Psychiatry 2022 Aug;16(8):902-911. Epub 2022 Jan 3 doi: 10.1111/eip.13238. PMID: 34978366
Zoghbi M, Haddad C, Hallit S, Nabout R, Medlej-Hashim M, Hachem D, Azar J
Nutr Neurosci 2020 Nov;23(11):911-919. Epub 2019 Feb 17 doi: 10.1080/1028415X.2019.1580830. PMID: 30774039
Goes FS, Pirooznia M, Parla JS, Kramer M, Ghiban E, Mavruk S, Chen YC, Monson ET, Willour VL, Karchin R, Flickinger M, Locke AE, Levy SE, Scott LJ, Boehnke M, Stahl E, Moran JL, Hultman CM, Landén M, Purcell SM, Sklar P, Zandi PP, McCombie WR, Potash JB
JAMA Psychiatry 2016 Jun 1;73(6):590-7. doi: 10.1001/jamapsychiatry.2016.0251. PMID: 27120077Free PMC Article

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...