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Focal hyperkinetic seizure

MedGen UID:
869079
•Concept ID:
C4023497
•
Disease or Syndrome
Synonym: Hyperkinetic seizures
SNOMED CT: Focal onset hyperkinetic seizure (1269371001); Focal hyperkinetic seizure (1269371001); Focal onset hyperkinetic epileptic seizure (1269371001); Focal-onset hyperkinetic epileptic seizure (1269371001); Focal hypermotor seizure (1269371001)
 
HPO: HP:0011174

Definition

A focal seizure characterized at onset by predominantly proximal limb or axial muscles producing irregular sequential ballistic movements, such as pedaling, pelvic thrusting, thrashing, rocking movements. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVFocal hyperkinetic seizure

Professional guidelines

PubMed

Surgical treatment of drug-resistant nocturnal frontal lobe epilepsy.
Nobili L, Francione S, Mai R, Cardinale F, Castana L, Tassi L, Sartori I, Didato G, Citterio A, Colombo N, Galli C, Lo Russo G, Cossu M
Brain 2007 Feb;130(Pt 2):561-73. Epub 2006 Nov 22 doi: 10.1093/brain/awl322. PMID: 17124189

Recent clinical studies

Etiology

Predictors of hyperkinetic seizures.
Menghi V, Bisulli F, Cardinale F, Vignatelli L, Zenesini C, Mai R, Proserpio P, Francione S, Sartori I, Tinuper P, Nobili L
Epilepsy Behav 2022 Apr;129:108629. Epub 2022 Mar 7 doi: 10.1016/j.yebeh.2022.108629. PMID: 35272206
Clinical characteristics and postoperative seizure outcome in patients with mild malformation of cortical development and oligodendroglial hyperplasia.
Gaballa A, Woermann FG, Cloppenborg T, Kalbhenn T, Blümcke I, Bien CG, Fauser S
Epilepsia 2021 Dec;62(12):2920-2931. Epub 2021 Oct 11 doi: 10.1111/epi.17084. PMID: 34636039
Prefrontal seizure classification based on stereo-EEG quantification and automatic clustering.
Machado S, Bonini F, McGonigal A, Singh R, Carron R, Scavarda D, Lagarde S, Trébuchon A, Giusiano B, Bartolomei F
Epilepsy Behav 2020 Nov;112:107436. Epub 2020 Sep 6 doi: 10.1016/j.yebeh.2020.107436. PMID: 32906017
Quantitative analysis of hyperkinetic seizures and correlation with seizure onset zone.
Fayerstein J, McGonigal A, Pizzo F, Bonini F, Lagarde S, Braquet A, Trébuchon A, Carron R, Scavarda D, Julia S, Lambert I, Giusiano B, Bartolomei F
Epilepsia 2020 May;61(5):1019-1026. Epub 2020 May 7 doi: 10.1111/epi.16510. PMID: 32378738
Anatomoelectroclinical features of SEEG-confirmed pure insular-onset epilepsy.
Peltola ME, Trébuchon A, Lagarde S, Scavarda D, Carron R, Metsähonkala L, Lauronen L, Lépine A, Villeneuve N, Bartolomei F
Epilepsy Behav 2020 Apr;105:106964. Epub 2020 Feb 22 doi: 10.1016/j.yebeh.2020.106964. PMID: 32092457

Diagnosis

Motor seizure semiology.
Wu S, Nordli DR
Handb Clin Neurol 2023;196:295-304. doi: 10.1016/B978-0-323-98817-9.00014-4. PMID: 37620075
Predictors of hyperkinetic seizures.
Menghi V, Bisulli F, Cardinale F, Vignatelli L, Zenesini C, Mai R, Proserpio P, Francione S, Sartori I, Tinuper P, Nobili L
Epilepsy Behav 2022 Apr;129:108629. Epub 2022 Mar 7 doi: 10.1016/j.yebeh.2022.108629. PMID: 35272206
Sleep-Related Hypermotor Epilepsy vs Disorders of Arousal in Adults: A Step-Wise Approach to Diagnosis.
Montini A, Loddo G, Baldelli L, Cilea R, Provini F
Chest 2021 Jul;160(1):319-329. Epub 2021 Jan 30 doi: 10.1016/j.chest.2021.01.059. PMID: 33529771
Quantitative analysis of hyperkinetic seizures and correlation with seizure onset zone.
Fayerstein J, McGonigal A, Pizzo F, Bonini F, Lagarde S, Braquet A, Trébuchon A, Carron R, Scavarda D, Julia S, Lambert I, Giusiano B, Bartolomei F
Epilepsia 2020 May;61(5):1019-1026. Epub 2020 May 7 doi: 10.1111/epi.16510. PMID: 32378738
Operational classification of seizure types by the International League Against Epilepsy: Position Paper of the ILAE Commission for Classification and Terminology.
Fisher RS, Cross JH, French JA, Higurashi N, Hirsch E, Jansen FE, Lagae L, Moshé SL, Peltola J, Roulet Perez E, Scheffer IE, Zuberi SM
Epilepsia 2017 Apr;58(4):522-530. Epub 2017 Mar 8 doi: 10.1111/epi.13670. PMID: 28276060

Therapy

Sulthiame use in children with pharmacoresistant epilepsies: A retrospective study.
Laliberté A, Berrahmoune S, Myers KA
Epileptic Disord 2024 Oct;26(5):591-599. Epub 2024 May 31 doi: 10.1002/epd2.20250. PMID: 38818757
Transcutaneous auricular vagus nerve stimulation therapy in patients with cognitively preserved structural focal epilepsy: A case series report.
Shiraishi H, Egawa K, Murakami K, Nakajima M, Ueda Y, Nakakubo S, Narugami M, Kimura S, Goto T, Hiramatsu Y, Murakami M
Brain Dev 2024 Jan;46(1):49-56. Epub 2023 Aug 30 doi: 10.1016/j.braindev.2023.08.007. PMID: 37657962
Surgical treatment of drug-resistant nocturnal frontal lobe epilepsy.
Nobili L, Francione S, Mai R, Cardinale F, Castana L, Tassi L, Sartori I, Didato G, Citterio A, Colombo N, Galli C, Lo Russo G, Cossu M
Brain 2007 Feb;130(Pt 2):561-73. Epub 2006 Nov 22 doi: 10.1093/brain/awl322. PMID: 17124189
Long-term anticonvulsant therapy in tuberculous meningitis--a four-year follow-up.
Patwari AK, Aneja S, Chandra D, Singhal PK
J Trop Pediatr 1996 Apr;42(2):98-103. doi: 10.1093/tropej/42.2.98. PMID: 8984222
Parietal lobe epilepsy: clinical features and seizure localization by ictal SPECT.
Ho SS, Berkovic SF, Newton MR, Austin MC, McKay WJ, Bladin PF
Neurology 1994 Dec;44(12):2277-84. doi: 10.1212/wnl.44.12.2277. PMID: 7991112

Prognosis

Predictors of hyperkinetic seizures.
Menghi V, Bisulli F, Cardinale F, Vignatelli L, Zenesini C, Mai R, Proserpio P, Francione S, Sartori I, Tinuper P, Nobili L
Epilepsy Behav 2022 Apr;129:108629. Epub 2022 Mar 7 doi: 10.1016/j.yebeh.2022.108629. PMID: 35272206
PIGN encephalopathy: Characterizing the epileptology.
Bayat A, de Valles-Ibáñez G, Pendziwiat M, Knaus A, Alt K, Biamino E, Bley A, Calvert S, Carney P, Caro-Llopis A, Ceulemans B, Cousin J, Davis S, des Portes V, Edery P, England E, Ferreira C, Freeman J, Gener B, Gorce M, Heron D, Hildebrand MS, Jezela-Stanek A, Jouk PS, Keren B, Kloth K, Kluger G, Kuhn M, Lemke JR, Li H, Martinez F, Maxton C, Mefford HC, Merla G, Mierzewska H, Muir A, Monfort S, Nicolai J, Norman J, O'Grady G, Oleksy B, Orellana C, Orec LE, Peinhardt C, Pronicka E, Rosello M, Santos-Simarro F, Schwaibold EMC, Stegmann APA, Stumpel CT, Szczepanik E, Terczyńska I, Thevenon J, Tzschach A, Van Bogaert P, Vittorini R, Walsh S, Weckhuysen S, Weissman B, Wolfe L, Reymond A, De Nittis P, Poduri A, Olson H, Striano P, Lesca G, Scheffer IE, Møller RS, Sadleir LG
Epilepsia 2022 Apr;63(4):974-991. Epub 2022 Feb 18 doi: 10.1111/epi.17173. PMID: 35179230
Clinical characteristics and postoperative seizure outcome in patients with mild malformation of cortical development and oligodendroglial hyperplasia.
Gaballa A, Woermann FG, Cloppenborg T, Kalbhenn T, Blümcke I, Bien CG, Fauser S
Epilepsia 2021 Dec;62(12):2920-2931. Epub 2021 Oct 11 doi: 10.1111/epi.17084. PMID: 34636039
Genetic Neonatal-Onset Epilepsies and Developmental/Epileptic Encephalopathies with Movement Disorders: A Systematic Review.
Spagnoli C, Fusco C, Percesepe A, Leuzzi V, Pisani F
Int J Mol Sci 2021 Apr 18;22(8) doi: 10.3390/ijms22084202. PMID: 33919646Free PMC Article
Quantitative analysis of hyperkinetic seizures and correlation with seizure onset zone.
Fayerstein J, McGonigal A, Pizzo F, Bonini F, Lagarde S, Braquet A, Trébuchon A, Carron R, Scavarda D, Julia S, Lambert I, Giusiano B, Bartolomei F
Epilepsia 2020 May;61(5):1019-1026. Epub 2020 May 7 doi: 10.1111/epi.16510. PMID: 32378738

Clinical prediction guides

Motor seizure semiology.
Wu S, Nordli DR
Handb Clin Neurol 2023;196:295-304. doi: 10.1016/B978-0-323-98817-9.00014-4. PMID: 37620075
Predictors of hyperkinetic seizures.
Menghi V, Bisulli F, Cardinale F, Vignatelli L, Zenesini C, Mai R, Proserpio P, Francione S, Sartori I, Tinuper P, Nobili L
Epilepsy Behav 2022 Apr;129:108629. Epub 2022 Mar 7 doi: 10.1016/j.yebeh.2022.108629. PMID: 35272206
PIGN encephalopathy: Characterizing the epileptology.
Bayat A, de Valles-Ibáñez G, Pendziwiat M, Knaus A, Alt K, Biamino E, Bley A, Calvert S, Carney P, Caro-Llopis A, Ceulemans B, Cousin J, Davis S, des Portes V, Edery P, England E, Ferreira C, Freeman J, Gener B, Gorce M, Heron D, Hildebrand MS, Jezela-Stanek A, Jouk PS, Keren B, Kloth K, Kluger G, Kuhn M, Lemke JR, Li H, Martinez F, Maxton C, Mefford HC, Merla G, Mierzewska H, Muir A, Monfort S, Nicolai J, Norman J, O'Grady G, Oleksy B, Orellana C, Orec LE, Peinhardt C, Pronicka E, Rosello M, Santos-Simarro F, Schwaibold EMC, Stegmann APA, Stumpel CT, Szczepanik E, Terczyńska I, Thevenon J, Tzschach A, Van Bogaert P, Vittorini R, Walsh S, Weckhuysen S, Weissman B, Wolfe L, Reymond A, De Nittis P, Poduri A, Olson H, Striano P, Lesca G, Scheffer IE, Møller RS, Sadleir LG
Epilepsia 2022 Apr;63(4):974-991. Epub 2022 Feb 18 doi: 10.1111/epi.17173. PMID: 35179230
Clinical characteristics and postoperative seizure outcome in patients with mild malformation of cortical development and oligodendroglial hyperplasia.
Gaballa A, Woermann FG, Cloppenborg T, Kalbhenn T, Blümcke I, Bien CG, Fauser S
Epilepsia 2021 Dec;62(12):2920-2931. Epub 2021 Oct 11 doi: 10.1111/epi.17084. PMID: 34636039
Quantitative analysis of hyperkinetic seizures and correlation with seizure onset zone.
Fayerstein J, McGonigal A, Pizzo F, Bonini F, Lagarde S, Braquet A, Trébuchon A, Carron R, Scavarda D, Julia S, Lambert I, Giusiano B, Bartolomei F
Epilepsia 2020 May;61(5):1019-1026. Epub 2020 May 7 doi: 10.1111/epi.16510. PMID: 32378738

Recent systematic reviews

Genetic Neonatal-Onset Epilepsies and Developmental/Epileptic Encephalopathies with Movement Disorders: A Systematic Review.
Spagnoli C, Fusco C, Percesepe A, Leuzzi V, Pisani F
Int J Mol Sci 2021 Apr 18;22(8) doi: 10.3390/ijms22084202. PMID: 33919646Free PMC Article

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