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Acinar Cell Neoplasm

MedGen UID:
87231
•Concept ID:
C0334390
•
Neoplastic Process
Synonyms: Acinar cell neoplasm; Acinar Cell Tumor
SNOMED CT: Acinar cell neoplasm (115219005)

Definition

A benign or malignant glandular epithelial neoplasm consisting of secretory cells forming acinar patterns. It includes the acinar cell adenoma and acinar cell carcinoma. [from NCI]

Professional guidelines

PubMed

Comprehensive review of pancreatic acinar cell carcinoma: epidemiology, diagnosis, molecular features and treatment.
Ikezawa K, Urabe M, Kai Y, Takada R, Akita H, Nagata S, Ohkawa K
Jpn J Clin Oncol 2024 Mar 9;54(3):271-281. doi: 10.1093/jjco/hyad176. PMID: 38109477Free PMC Article
A Simple Overview of Pancreatic Cancer Treatment for Clinical Oncologists.
Garajová I, Peroni M, Gelsomino F, Leonardi F
Curr Oncol 2023 Oct 31;30(11):9587-9601. doi: 10.3390/curroncol30110694. PMID: 37999114Free PMC Article
Immune infiltrates and PD-L1 expression in treatment-naïve acinar prostatic adenocarcinoma: an exploratory analysis.
Hahn E, Liu SK, Vesprini D, Xu B, Downes MR
J Clin Pathol 2018 Nov;71(11):1023-1027. Epub 2018 Sep 26 doi: 10.1136/jclinpath-2018-205404. PMID: 30257853

Recent clinical studies

Etiology

Post-obstructive cyst formation in pancreas and cystic acinar transformation: Are they same?
Zhang X, Zhu H, Yang X, Adsay VN, Jain D
Pathol Res Pract 2017 Aug;213(8):997-1001. Epub 2017 Apr 1 doi: 10.1016/j.prp.2017.03.013. PMID: 28599853

Diagnosis

Post-obstructive cyst formation in pancreas and cystic acinar transformation: Are they same?
Zhang X, Zhu H, Yang X, Adsay VN, Jain D
Pathol Res Pract 2017 Aug;213(8):997-1001. Epub 2017 Apr 1 doi: 10.1016/j.prp.2017.03.013. PMID: 28599853
Cytomorphologic and immunophenotypical features of acinar cell neoplasms of the pancreas.
Sigel CS, Klimstra DS
Cancer Cytopathol 2013 Aug;121(8):459-70. Epub 2013 Feb 13 doi: 10.1002/cncy.21279. PMID: 23408736
Primary pancreatic cystic neoplasms of the pancreas revisited. Part IV: rare cystic neoplasms.
Sakorafas GH, Smyrniotis V, Reid-Lombardo KM, Sarr MG
Surg Oncol 2012 Sep;21(3):153-63. Epub 2011 Aug 3 doi: 10.1016/j.suronc.2011.06.007. PMID: 21816607

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