Name: rs12425225
Published: September 21, 2022
License: Open Access

Welcome to the Reference SNP (rs) Report

All alleles are reported in the Forward orientation. Click on the Variant Details tab for details on Genomic Placement, Gene, and Amino Acid changes. HGVS names are in the HGVS tab.

Reference SNP (rs) Report

This page reports data for a single dbSNP Reference SNP variation (RefSNP or rs) from the new redesigned dbSNP build.
Top of the page reports a concise summary for the rs, with more specific details included in the corresponding tabs below.
All alleles are reported in the Forward orientation. Use the Genomic View to inspect the nucleotides flanking the variant, and its neighbors.
For more information see Help documentation.

rs12425225

Current Build 156

Released September 21, 2022

Organism: Homo sapiens
Position: chr12:52331517 (GRCh38.p14) Help
The anchor position for this RefSNP. Includes all nucleotides potentially affected by this change, thus it can differ from HGVS, which is right-shifted. See here for details.
Alleles: C>A / C>G / C>T
Variation Type: SNV Single Nucleotide Variation
Frequency: A=0.365580 (107923/295210, ALFA)
A=0.433144 (114649/264690, TOPMED)
A=0.375841 (77076/205076, GENOGRAPHIC) (+ 22 more)
C=0.49146 (38676/78696, PAGE_STUDY)
C=0.30657 (8663/28258, 14KJPN)
C=0.30579 (5125/16760, 8.3KJPN)
A=0.4744 (3038/6404, 1000G_30x)
A=0.4734 (2371/5008, 1000G)
A=0.4246 (1902/4480, Estonian)
A=0.3664 (1412/3854, ALSPAC)
A=0.3706 (1374/3708, TWINSUK)
C=0.3648 (1069/2930, KOREAN)
A=0.4971 (1036/2084, HGDP_Stanford)
A=0.4725 (894/1892, HapMap)
C=0.3515 (644/1832, Korea1K)
A=0.346 (345/998, GoNL)
C=0.385 (305/792, PRJEB37584)
A=0.486 (304/626, Chileans)
A=0.322 (193/600, NorthernSweden)
C=0.328 (131/400, SGDP_PRJ)
A=0.301 (65/216, Qatari)
C=0.310 (67/216, Vietnamese)
A=0.33 (20/60, Ancient Sardinia)
A=0.30 (12/40, GENOME_DK)
C=0.33 (12/36, Siberian)

Clinical Significance: Not Reported in ClinVar
Gene : Consequence: None
Publications: 0 citations
Genomic View: See rs on genome

ALFA Allele Frequency
The ALFA project provide aggregate allele frequency from dbGaP. More information is available on the project page including descriptions, data access, and terms of use.

Release Version: 20231103111315

Population	Group	Sample Size	Ref Allele	Alt Allele	Ref HMOZ	Alt HMOZ	HTRZ	HWEP
Total	Global	300242	C=0.633919	A=0.366081, T=0.000000	0.406865	0.139028	0.454107	32
European	Sub	266936	C=0.643761	A=0.356239, T=0.000000	0.416152	0.12863	0.455218	5
African	Sub	8136	C=0.5624	A=0.4376, T=0.0000	0.337266	0.212389	0.450344	16
African Others	Sub	304	C=0.526	A=0.474, T=0.000	0.282895	0.230263	0.486842	0
African American	Sub	7832	C=0.5638	A=0.4362, T=0.0000	0.339377	0.211696	0.448927	16
Asian	Sub	3890	C=0.3542	A=0.6458, T=0.0000	0.13419	0.425707	0.440103	2
East Asian	Sub	3134	C=0.3500	A=0.6500, T=0.0000	0.129547	0.429483	0.44097	1
Other Asian	Sub	756	C=0.372	A=0.628, T=0.000	0.153439	0.410053	0.436508	1
Latin American 1	Sub	1140	C=0.6105	A=0.3895, T=0.0000	0.384211	0.163158	0.452632	1
Latin American 2	Sub	4818	C=0.4639	A=0.5361, T=0.0000	0.231216	0.303445	0.465338	6
South Asian	Sub	5182	C=0.6741	A=0.3259, T=0.0000	0.464685	0.116557	0.418757	4
Other	Sub	10140	C=0.60237	A=0.39763, T=0.00000	0.37929	0.174556	0.446154	13

Frequency tab displays a table of the reference and alternate allele frequencies reported by various studies and populations. Table lines, where Population="Global" refer to the entire study population, whereas lines, where Group="Sub", refer to a study-specific population subgroupings (i.e. AFR, CAU, etc.), if available. Frequency for the alternate allele (Alt Allele) is a ratio of samples observed-to-total, where the numerator (observed samples) is the number of chromosomes in the study with the minor allele present (found in "Sample size", where Group="Sub"), and the denominator (total samples) is the total number of all chromosomes in the study for the variant (found in "Sample size", where Group="Study-wide" and Population="Global").

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Study	Population	Group	Sample Size	Ref Allele	Alt Allele
Allele Frequency Aggregator	Total	Global	295210	C=0.634420	A=0.365580, T=0.000000
Allele Frequency Aggregator	European	Sub	263842	C=0.643806	A=0.356194, T=0.000000
Allele Frequency Aggregator	Other	Sub	9340	C=0.6049	A=0.3951, T=0.0000
Allele Frequency Aggregator	African	Sub	6998	C=0.5676	A=0.4324, T=0.0000
Allele Frequency Aggregator	South Asian	Sub	5182	C=0.6741	A=0.3259, T=0.0000
Allele Frequency Aggregator	Latin American 2	Sub	4818	C=0.4639	A=0.5361, T=0.0000
Allele Frequency Aggregator	Asian	Sub	3890	C=0.3542	A=0.6458, T=0.0000
Allele Frequency Aggregator	Latin American 1	Sub	1140	C=0.6105	A=0.3895, T=0.0000
TopMed	Global	Study-wide	264690	C=0.566856	A=0.433144
Genographic Project	Global	Study-wide	205076	C=0.624159	A=0.375841, T=0.000000
The PAGE Study	Global	Study-wide	78696	C=0.49146	A=0.50854
The PAGE Study	AfricanAmerican	Sub	32512	C=0.51836	A=0.48164
The PAGE Study	Mexican	Sub	10810	C=0.42618	A=0.57382
The PAGE Study	Asian	Sub	8318	C=0.3210	A=0.6790
The PAGE Study	PuertoRican	Sub	7916	C=0.5546	A=0.4454
The PAGE Study	NativeHawaiian	Sub	4534	C=0.4751	A=0.5249
The PAGE Study	Cuban	Sub	4230	C=0.6137	A=0.3863
The PAGE Study	Dominican	Sub	3828	C=0.5789	A=0.4211
The PAGE Study	CentralAmerican	Sub	2450	C=0.4282	A=0.5718
The PAGE Study	SouthAmerican	Sub	1982	C=0.4612	A=0.5388
The PAGE Study	NativeAmerican	Sub	1260	C=0.5349	A=0.4651
The PAGE Study	SouthAsian	Sub	856	C=0.646	A=0.354
14KJPN	JAPANESE	Study-wide	28258	C=0.30657	A=0.69343
8.3KJPN	JAPANESE	Study-wide	16760	C=0.30579	A=0.69421
1000Genomes_30x	Global	Study-wide	6404	C=0.5256	A=0.4744
1000Genomes_30x	African	Sub	1786	C=0.4955	A=0.5045
1000Genomes_30x	Europe	Sub	1266	C=0.6374	A=0.3626
1000Genomes_30x	South Asian	Sub	1202	C=0.6839	A=0.3161
1000Genomes_30x	East Asian	Sub	1170	C=0.3162	A=0.6838
1000Genomes_30x	American	Sub	980	C=0.492	A=0.508
1000Genomes	Global	Study-wide	5008	C=0.5266	A=0.4734
1000Genomes	African	Sub	1322	C=0.5023	A=0.4977
1000Genomes	East Asian	Sub	1008	C=0.3185	A=0.6815
1000Genomes	Europe	Sub	1006	C=0.6342	A=0.3658
1000Genomes	South Asian	Sub	978	C=0.680	A=0.320
1000Genomes	American	Sub	694	C=0.503	A=0.497
Genetic variation in the Estonian population	Estonian	Study-wide	4480	C=0.5754	A=0.4246
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	C=0.6336	A=0.3664
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	C=0.6294	A=0.3706
KOREAN population from KRGDB	KOREAN	Study-wide	2930	C=0.3648	A=0.6352, G=0.0000, T=0.0000
HGDP-CEPH-db Supplement 1	Global	Study-wide	2084	C=0.5029	A=0.4971
HGDP-CEPH-db Supplement 1	Est_Asia	Sub	470	C=0.368	A=0.632
HGDP-CEPH-db Supplement 1	Central_South_Asia	Sub	414	C=0.635	A=0.365
HGDP-CEPH-db Supplement 1	Middle_Est	Sub	350	C=0.677	A=0.323
HGDP-CEPH-db Supplement 1	Europe	Sub	320	C=0.597	A=0.403
HGDP-CEPH-db Supplement 1	Africa	Sub	242	C=0.537	A=0.463
HGDP-CEPH-db Supplement 1	America	Sub	216	C=0.093	A=0.907
HGDP-CEPH-db Supplement 1	Oceania	Sub	72	C=0.47	A=0.53
HapMap	Global	Study-wide	1892	C=0.5275	A=0.4725
HapMap	American	Sub	770	C=0.558	A=0.442
HapMap	African	Sub	692	C=0.540	A=0.460
HapMap	Asian	Sub	254	C=0.280	A=0.720
HapMap	Europe	Sub	176	C=0.699	A=0.301
Korean Genome Project	KOREAN	Study-wide	1832	C=0.3515	A=0.6485
Genome of the Netherlands Release 5	Genome of the Netherlands	Study-wide	998	C=0.654	A=0.346
CNV burdens in cranial meningiomas	Global	Study-wide	792	C=0.385	A=0.615
CNV burdens in cranial meningiomas	CRM	Sub	792	C=0.385	A=0.615
Chileans	Chilean	Study-wide	626	C=0.514	A=0.486
Northern Sweden	ACPOP	Study-wide	600	C=0.678	A=0.322
SGDP_PRJ	Global	Study-wide	400	C=0.328	A=0.672
Qatari	Global	Study-wide	216	C=0.699	A=0.301
A Vietnamese Genetic Variation Database	Global	Study-wide	216	C=0.310	A=0.690
Ancient Sardinia genome-wide 1240k capture data generation and analysis	Global	Study-wide	60	C=0.67	A=0.33
The Danish reference pan genome	Danish	Study-wide	40	C=0.70	A=0.30
Siberian	Global	Study-wide	36	C=0.33	A=0.67

Variant Details tab shows known variant placements on genomic sequences: chromosomes (NC_), RefSeqGene, pseudogenes or genomic regions (NG_), and in a separate table: on transcripts (NM_) and protein sequences (NP_). The corresponding transcript and protein locations are listed in adjacent lines, along with molecular consequences from Sequence Ontology. When no protein placement is available, only the transcript is listed. Column "Codon[Amino acid]" shows the actual base change in the format of "Reference > Alternate" allele, including the nucleotide codon change in transcripts, and the amino acid change in proteins, respectively, allowing for known ribosomal slippage sites. To view nucleotides adjacent to the variant use the Genomic View at the bottom of the page - zoom into the sequence until the nucleotides around the variant become visible.

Genomic Placements

Sequence name	Change
GRCh38.p14 chr 12	NC_000012.12:g.52331517C>A
GRCh38.p14 chr 12	NC_000012.12:g.52331517C>G
GRCh38.p14 chr 12	NC_000012.12:g.52331517C>T
GRCh37.p13 chr 12	NC_000012.11:g.52725301C>A
GRCh37.p13 chr 12	NC_000012.11:g.52725301C>G
GRCh37.p13 chr 12	NC_000012.11:g.52725301C>T

Clinical Significance tab shows a list of clinical significance entries from ClinVar associated with the variation, per allele. Click on the RCV accession (i.e. RCV000001615.2) or Allele ID (i.e. 12274) to access full ClinVar report.

Not Reported in ClinVar

Aliases tab displays HGVS names representing the variant placements and allele changes on genomic, transcript and protein sequences, per allele. HGVS name is an expression for reporting sequence accession and version, sequence type, position, and allele change. The column "Note" can have two values: "diff" means that there is a difference between the reference allele (variation interval) at the placement reported in HGVS name and the reference alleles reported in other HGVS names, and "rev" means that the sequence of this variation interval at the placement reported in HGVS name is in reverse orientation to the sequence(s) of this variation in other HGVS names not labeled as "rev".

Placement	C=	A	G	T
GRCh38.p14 chr 12	NC_000012.12:g.52331517=	NC_000012.12:g.52331517C>A	NC_000012.12:g.52331517C>G	NC_000012.12:g.52331517C>T
GRCh37.p13 chr 12	NC_000012.11:g.52725301=	NC_000012.11:g.52725301C>A	NC_000012.11:g.52725301C>G	NC_000012.11:g.52725301C>T

Submissions tab displays variations originally submitted to dbSNP, now supporting this RefSNP cluster (rs). We display Submitter handle, Submission identifier, Date and Build number, when the submission appeared for the first time. Direct submissions to dbSNP have Submission ID in the form of an ss-prefixed number (ss#). Other supporting variations are listed in the table without ss#.

133 SubSNP, 27 Frequency submissions

No	Submitter	Submission ID	Date (Build)
1	CSHL-HAPMAP	ss19245709	Feb 28, 2004 (120)
2	PERLEGEN	ss23355501	Sep 20, 2004 (123)
3	AFFY	ss66164432	Nov 30, 2006 (127)
4	ILLUMINA	ss66734495	Nov 30, 2006 (127)
5	ILLUMINA	ss67005175	Nov 30, 2006 (127)
6	ILLUMINA	ss67324128	Nov 30, 2006 (127)
7	ILLUMINA	ss70409229	May 17, 2007 (127)
8	ILLUMINA	ss70567312	May 26, 2008 (130)
9	ILLUMINA	ss71107454	May 17, 2007 (127)
10	ILLUMINA	ss75732667	Dec 07, 2007 (129)
11	AFFY	ss76210955	Dec 07, 2007 (129)
12	HGSV	ss82709470	Dec 15, 2007 (130)
13	KRIBB_YJKIM	ss85218386	Dec 15, 2007 (130)
14	BCMHGSC_JDW	ss89153528	Mar 24, 2008 (129)
15	BGI	ss106806411	Feb 06, 2009 (130)
16	1000GENOMES	ss113545901	Jan 25, 2009 (130)
17	ILLUMINA-UK	ss118807369	Feb 14, 2009 (130)
18	ILLUMINA	ss121561547	Dec 01, 2009 (131)
19	ENSEMBL	ss133167928	Dec 01, 2009 (131)
20	ILLUMINA	ss153192267	Dec 01, 2009 (131)
21	ILLUMINA	ss159216152	Dec 01, 2009 (131)
22	ILLUMINA	ss160057155	Dec 01, 2009 (131)
23	ENSEMBL	ss161532275	Dec 01, 2009 (131)
24	COMPLETE_GENOMICS	ss169847361	Jul 04, 2010 (132)
25	ILLUMINA	ss170117953	Jul 04, 2010 (132)
26	ILLUMINA	ss172067371	Jul 04, 2010 (132)
27	AFFY	ss172825776	Jul 04, 2010 (132)
28	BUSHMAN	ss198183225	Jul 04, 2010 (132)
29	1000GENOMES	ss210817716	Jul 14, 2010 (132)
30	1000GENOMES	ss225755053	Jul 14, 2010 (132)
31	1000GENOMES	ss235936421	Jul 15, 2010 (132)
32	1000GENOMES	ss242495540	Jul 15, 2010 (132)
33	BL	ss255121174	May 09, 2011 (134)
34	GMI	ss281398047	May 04, 2012 (137)
35	GMI	ss286562083	Apr 25, 2013 (138)
36	PJP	ss291251251	May 09, 2011 (134)
37	ILLUMINA	ss479734461	May 04, 2012 (137)
38	ILLUMINA	ss479740260	May 04, 2012 (137)
39	ILLUMINA	ss480294001	Sep 08, 2015 (146)
40	ILLUMINA	ss484665538	May 04, 2012 (137)
41	ILLUMINA	ss536779891	Sep 08, 2015 (146)
42	TISHKOFF	ss563168489	Apr 25, 2013 (138)
43	SSMP	ss658724182	Apr 25, 2013 (138)
44	ILLUMINA	ss778780965	Sep 08, 2015 (146)
45	ILLUMINA	ss782779626	Sep 08, 2015 (146)
46	ILLUMINA	ss783745598	Sep 08, 2015 (146)
47	ILLUMINA	ss825378503	Apr 01, 2015 (144)
48	ILLUMINA	ss832032193	Sep 08, 2015 (146)
49	ILLUMINA	ss832728553	Jul 13, 2019 (153)
50	ILLUMINA	ss834240908	Sep 08, 2015 (146)
51	EVA-GONL	ss989537892	Aug 21, 2014 (142)
52	JMKIDD_LAB	ss1078463785	Aug 21, 2014 (142)
53	1000GENOMES	ss1345033302	Aug 21, 2014 (142)
54	DDI	ss1426934404	Apr 01, 2015 (144)
55	EVA_GENOME_DK	ss1576285713	Apr 01, 2015 (144)
56	EVA_DECODE	ss1599209419	Apr 01, 2015 (144)
57	EVA_UK10K_ALSPAC	ss1628599952	Apr 01, 2015 (144)
58	EVA_UK10K_TWINSUK	ss1671593985	Apr 01, 2015 (144)
59	EVA_SVP	ss1713327898	Apr 01, 2015 (144)
60	ILLUMINA	ss1752071307	Sep 08, 2015 (146)
61	HAMMER_LAB	ss1807247383	Sep 08, 2015 (146)
62	WEILL_CORNELL_DGM	ss1932902318	Feb 12, 2016 (147)
63	ILLUMINA	ss1946338798	Feb 12, 2016 (147)
64	ILLUMINA	ss1959434898	Feb 12, 2016 (147)
65	GENOMED	ss1967590676	Jul 19, 2016 (147)
66	JJLAB	ss2027202194	Sep 14, 2016 (149)
67	USC_VALOUEV	ss2155540238	Dec 20, 2016 (150)
68	HUMAN_LONGEVITY	ss2189824804	Dec 20, 2016 (150)
69	SYSTEMSBIOZJU	ss2628081834	Nov 08, 2017 (151)
70	ILLUMINA	ss2632959729	Nov 08, 2017 (151)
71	GRF	ss2699883625	Nov 08, 2017 (151)
72	ILLUMINA	ss2710761958	Nov 08, 2017 (151)
73	GNOMAD	ss2910553713	Nov 08, 2017 (151)
74	SWEGEN	ss3009695732	Nov 08, 2017 (151)
75	ILLUMINA	ss3021431053	Nov 08, 2017 (151)
76	BIOINF_KMB_FNS_UNIBA	ss3027409568	Nov 08, 2017 (151)
77	CSHL	ss3350065973	Nov 08, 2017 (151)
78	ILLUMINA	ss3625623355	Oct 12, 2018 (152)
79	ILLUMINA	ss3626878160	Oct 12, 2018 (152)
80	ILLUMINA	ss3630968869	Oct 12, 2018 (152)
81	ILLUMINA	ss3633020483	Oct 12, 2018 (152)
82	ILLUMINA	ss3633721442	Oct 12, 2018 (152)
83	ILLUMINA	ss3634504557	Oct 12, 2018 (152)
84	ILLUMINA	ss3635412202	Oct 12, 2018 (152)
85	ILLUMINA	ss3636189970	Oct 12, 2018 (152)
86	ILLUMINA	ss3637163188	Oct 12, 2018 (152)
87	ILLUMINA	ss3637963271	Oct 12, 2018 (152)
88	ILLUMINA	ss3638995415	Oct 12, 2018 (152)
89	ILLUMINA	ss3639499863	Oct 12, 2018 (152)
90	ILLUMINA	ss3640211890	Oct 12, 2018 (152)
91	ILLUMINA	ss3641030443	Oct 12, 2018 (152)
92	ILLUMINA	ss3641325164	Oct 12, 2018 (152)
93	ILLUMINA	ss3642956881	Oct 12, 2018 (152)
94	ILLUMINA	ss3644591795	Oct 12, 2018 (152)
95	ILLUMINA	ss3651808194	Oct 12, 2018 (152)
96	EGCUT_WGS	ss3676967888	Jul 13, 2019 (153)
97	EVA_DECODE	ss3693679621	Jul 13, 2019 (153)
98	ILLUMINA	ss3725325261	Jul 13, 2019 (153)
99	ACPOP	ss3739025717	Jul 13, 2019 (153)
100	ILLUMINA	ss3744099314	Jul 13, 2019 (153)
101	ILLUMINA	ss3744805239	Jul 13, 2019 (153)
102	EVA	ss3750485360	Jul 13, 2019 (153)
103	PAGE_CC	ss3771691233	Jul 13, 2019 (153)
104	ILLUMINA	ss3772304710	Jul 13, 2019 (153)
105	PACBIO	ss3787227887	Jul 13, 2019 (153)
106	PACBIO	ss3792329337	Jul 13, 2019 (153)
107	PACBIO	ss3797212124	Jul 13, 2019 (153)
108	KHV_HUMAN_GENOMES	ss3815814593	Jul 13, 2019 (153)
109	EVA	ss3833125147	Apr 27, 2020 (154)
110	HGDP	ss3847450879	Apr 27, 2020 (154)
111	SGDP_PRJ	ss3878282951	Apr 27, 2020 (154)
112	KRGDB	ss3926915993	Apr 27, 2020 (154)
113	KOGIC	ss3971943812	Apr 27, 2020 (154)
114	EVA	ss3984666911	Apr 26, 2021 (155)
115	EVA	ss3985591186	Apr 26, 2021 (155)
116	TOPMED	ss4918447938	Apr 26, 2021 (155)
117	TOMMO_GENOMICS	ss5206342512	Apr 26, 2021 (155)
118	1000G_HIGH_COVERAGE	ss5290825239	Oct 13, 2022 (156)
119	GENOGRAPHIC	ss5314551146	Oct 13, 2022 (156)
120	EVA	ss5315621046	Oct 13, 2022 (156)
121	EVA	ss5405664581	Oct 13, 2022 (156)
122	HUGCELL_USP	ss5485576913	Oct 13, 2022 (156)
123	EVA	ss5510705766	Oct 13, 2022 (156)
124	1000G_HIGH_COVERAGE	ss5588319565	Oct 13, 2022 (156)
125	SANFORD_IMAGENETICS	ss5653162194	Oct 13, 2022 (156)
126	TOMMO_GENOMICS	ss5756140427	Oct 13, 2022 (156)
127	EVA	ss5799872319	Oct 13, 2022 (156)
128	YY_MCH	ss5813302319	Oct 13, 2022 (156)
129	EVA	ss5837972255	Oct 13, 2022 (156)
130	EVA	ss5847669673	Oct 13, 2022 (156)
131	EVA	ss5850383099	Oct 13, 2022 (156)
132	EVA	ss5904411046	Oct 13, 2022 (156)
133	EVA	ss5944525429	Oct 13, 2022 (156)
134	1000Genomes	NC_000012.11 - 52725301	Oct 12, 2018 (152)
135	1000Genomes_30x	NC_000012.12 - 52331517	Oct 13, 2022 (156)
136	The Avon Longitudinal Study of Parents and Children	NC_000012.11 - 52725301	Oct 12, 2018 (152)
137	Chileans	NC_000012.11 - 52725301	Apr 27, 2020 (154)
138	Genetic variation in the Estonian population	NC_000012.11 - 52725301	Oct 12, 2018 (152)
139	Genographic Project	NC_000012.12 - 52331517	Oct 13, 2022 (156)
140	The Danish reference pan genome	NC_000012.11 - 52725301	Apr 27, 2020 (154)
141	gnomAD - Genomes Submission ignored due to conflicting rows: Row 407470538 (NC_000012.12:52331516:C:A 59179/139976) Row 407470539 (NC_000012.12:52331516:C:T 1/140034)	-	Apr 26, 2021 (155)
142	gnomAD - Genomes Submission ignored due to conflicting rows: Row 407470538 (NC_000012.12:52331516:C:A 59179/139976) Row 407470539 (NC_000012.12:52331516:C:T 1/140034)	-	Apr 26, 2021 (155)
143	Genome of the Netherlands Release 5	NC_000012.11 - 52725301	Apr 27, 2020 (154)
144	HGDP-CEPH-db Supplement 1	NC_000012.10 - 51011568	Apr 27, 2020 (154)
145	HapMap	NC_000012.12 - 52331517	Apr 27, 2020 (154)
146	KOREAN population from KRGDB	NC_000012.11 - 52725301	Apr 27, 2020 (154)
147	Korean Genome Project	NC_000012.12 - 52331517	Apr 27, 2020 (154)
148	Northern Sweden	NC_000012.11 - 52725301	Jul 13, 2019 (153)
149	The PAGE Study	NC_000012.12 - 52331517	Jul 13, 2019 (153)
150	Ancient Sardinia genome-wide 1240k capture data generation and analysis	NC_000012.11 - 52725301	Apr 26, 2021 (155)
151	CNV burdens in cranial meningiomas	NC_000012.11 - 52725301	Apr 26, 2021 (155)
152	Qatari	NC_000012.11 - 52725301	Apr 27, 2020 (154)
153	SGDP_PRJ	NC_000012.11 - 52725301	Apr 27, 2020 (154)
154	Siberian	NC_000012.11 - 52725301	Apr 27, 2020 (154)
155	8.3KJPN	NC_000012.11 - 52725301	Apr 26, 2021 (155)
156	14KJPN	NC_000012.12 - 52331517	Oct 13, 2022 (156)
157	TopMed	NC_000012.12 - 52331517	Apr 26, 2021 (155)
158	UK 10K study - Twins	NC_000012.11 - 52725301	Oct 12, 2018 (152)
159	A Vietnamese Genetic Variation Database	NC_000012.11 - 52725301	Jul 13, 2019 (153)
160	ALFA	NC_000012.12 - 52331517	Apr 26, 2021 (155)

History tab displays RefSNPs (Associated ID) from previous builds (Build) that now support the current RefSNP, and the dates, when the history was updated for each Associated ID (History Updated).

Associated ID	History Updated (Build)
rs60528021	May 26, 2008 (130)

Added to this RefSNP Cluster:

Submission IDs	Observation SPDI	Canonical SPDI	Source RSIDs
ss82709470, ss3638995415, ss3639499863	NC_000012.9:51011567:C:A	NC_000012.12:52331516:C:A	(self)
128771, ss66164432, ss76210955, ss89153528, ss113545901, ss118807369, ss169847361, ss172825776, ss198183225, ss210817716, ss255121174, ss281398047, ss286562083, ss291251251, ss479734461, ss825378503, ss1599209419, ss1713327898, ss3642956881, ss3847450879	NC_000012.10:51011567:C:A	NC_000012.12:52331516:C:A	(self)
57783009, 32085239, 99298, 22706136, 2965317, 14317724, 34093387, 12310582, 817113, 216404, 14944248, 30299931, 8056592, 64311819, 32085239, 7122708, ss225755053, ss235936421, ss242495540, ss479740260, ss480294001, ss484665538, ss536779891, ss563168489, ss658724182, ss778780965, ss782779626, ss783745598, ss832032193, ss832728553, ss834240908, ss989537892, ss1078463785, ss1345033302, ss1426934404, ss1576285713, ss1628599952, ss1671593985, ss1752071307, ss1807247383, ss1932902318, ss1946338798, ss1959434898, ss1967590676, ss2027202194, ss2155540238, ss2628081834, ss2632959729, ss2699883625, ss2710761958, ss2910553713, ss3009695732, ss3021431053, ss3350065973, ss3625623355, ss3626878160, ss3630968869, ss3633020483, ss3633721442, ss3634504557, ss3635412202, ss3636189970, ss3637163188, ss3637963271, ss3640211890, ss3641030443, ss3641325164, ss3644591795, ss3651808194, ss3676967888, ss3739025717, ss3744099314, ss3744805239, ss3750485360, ss3772304710, ss3787227887, ss3792329337, ss3797212124, ss3833125147, ss3878282951, ss3926915993, ss3984666911, ss3985591186, ss5206342512, ss5315621046, ss5405664581, ss5510705766, ss5653162194, ss5799872319, ss5837972255, ss5847669673, ss5944525429	NC_000012.11:52725300:C:A	NC_000012.12:52331516:C:A	(self)
75845500, 46262, 816882, 28321813, 912702, 89977531, 133993595, 445766804, ss2189824804, ss3027409568, ss3693679621, ss3725325261, ss3771691233, ss3815814593, ss3971943812, ss4918447938, ss5290825239, ss5314551146, ss5485576913, ss5588319565, ss5756140427, ss5813302319, ss5850383099, ss5904411046	NC_000012.12:52331516:C:A	NC_000012.12:52331516:C:A	(self)
ss19245709	NT_029419.10:14868606:C:A	NC_000012.12:52331516:C:A	(self)
ss23355501, ss66734495, ss67005175, ss67324128, ss70409229, ss70567312, ss71107454, ss75732667, ss85218386, ss106806411, ss121561547, ss133167928, ss153192267, ss159216152, ss160057155, ss161532275, ss170117953, ss172067371	NT_029419.12:14868606:C:A	NC_000012.12:52331516:C:A	(self)
34093387, ss3926915993	NC_000012.11:52725300:C:G	NC_000012.12:52331516:C:G	(self)
34093387, ss3926915993	NC_000012.11:52725300:C:T	NC_000012.12:52331516:C:T	(self)
46262, 445766804, ss5314551146	NC_000012.12:52331516:C:T	NC_000012.12:52331516:C:T	(self)

Publications tab displays PubMed articles citing the variation as a listing of PMID, Title, Author, Year, Journal, ordered by Year, descending.

No publications for rs12425225

The Flanks tab provides retrieving flanking sequences of a SNP on all molecules that have placements.

Genome context:

Select flank length:

Genomic regions, transcripts, and products
Top▲ Help
NCBI Graphical Sequence Viewer display of the genomic region, transcripts and protein products for the reported RefSNP (rs).
Use the zoom option to view the nucleotides around the RefSNP and find other neighboring RefSNPs.
Visit Sequence Viewer for help with navigating inside the display and modifying the selection of displayed data tracks.

Choose placement

dbSNP Short Genetic Variations

Welcome to the Reference SNP (rs) Report

Reference SNP (rs) Report

rs12425225