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BOR1 Bor1p [ Saccharomyces cerevisiae S288C ]

Gene ID: 855446, updated on 9-Dec-2024

Summary

Official Symbol
BOR1
Official Full Name
Bor1p
Primary source
SGD:S000005219
Locus tag
YNL275W
See related
AllianceGenome:SGD:S000005219; FungiDB:YNL275W; VEuPathDB:YNL275W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Enables borate efflux transmembrane transporter activity. Involved in borate transport and protein targeting to vacuole. Located in fungal-type vacuole and plasma membrane. Used to study anemia; hereditary spherocytosis; and renal tubular acidosis. Human ortholog(s) of this gene implicated in congenital hemolytic anemia (multiple); corneal dystrophy-perceptive deafness syndrome; corneal endothelial dystrophy (multiple); osteopetrosis; and renal tubular acidosis. Orthologous to several human genes including SLC4A9 (solute carrier family 4 member 9). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

See BOR1 in Genome Data Viewer
Location:
chromosome: XIV
Exon count:
1
Sequence:
Chromosome: XIV; NC_001146.8 (119268..120998)

Chromosome XIV - NC_001146.8Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene homoserine O-acetyltransferase Neighboring gene glyoxylate reductase Neighboring gene Tof1p

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

General gene information

Gene Ontology Provided by SGD

Process Evidence Code Pubs
involved_in borate transmembrane transport  
involved_in borate transport  
involved_in borate transport PubMed 
involved_in borate transport PubMed 
involved_in monoatomic anion transport  
involved_in monoatomic ion homeostasis  
involved_in monoatomic ion transport  
involved_in protein targeting to vacuole PubMed 
involved_in transmembrane transport  
Component Evidence Code Pubs
located_in cell periphery PubMed 
is_active_in fungal-type vacuole  
located_in fungal-type vacuole PubMed 
located_in membrane  
located_in membrane PubMed 
is_active_in plasma membrane  
located_in plasma membrane PubMed 
located_in plasma membrane  
located_in vacuolar membrane  
located_in vacuole  

General protein information

Preferred Names
Bor1p
NP_014124.1
  • Boron efflux transporter of the plasma membrane; binds HCO3-, I-, Br-, NO3- and Cl-; has similarity to the characterized boron efflux transporter A. thaliana BOR1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001146.8 Reference assembly

    Range
    119268..120998
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001183113.1 → NP_014124.1  TPA: Bor1p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_014124.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6W0R9, P53838
    UniProtKB/TrEMBL
    A6ZRG9, B3LPB4, B5VQD9, C7GP88, C8ZGP7, G2WLJ1
    Conserved Domains (1) summary
    cl23746
    Location:61 → 475
    Xan_ur_permease; Permease family
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