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    OYE3 NADPH dehydrogenase [ Saccharomyces cerevisiae S288C ]

    Gene ID: 855932, updated on 9-Dec-2024

    Summary

    Official Symbol
    OYE3
    Official Full Name
    NADPH dehydrogenase
    Primary source
    SGD:S000006092
    Locus tag
    YPL171C
    See related
    AllianceGenome:SGD:S000006092; FungiDB:YPL171C; VEuPathDB:YPL171C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    ZRG6
    Summary
    Enables NADPH dehydrogenase activity. Involved in apoptotic process. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See OYE3 in Genome Data Viewer
    Location:
    chromosome: XVI
    Exon count:
    1
    Sequence:
    Chromosome: XVI; NC_001148.4 (226169..227371, complement)

    Chromosome XVI - NC_001148.4Genomic Context describing neighboring genes Neighboring gene mitochondrial 54S ribosomal protein YmL40 Neighboring gene protoheme IX farnesyltransferase Neighboring gene Dap1p Neighboring gene Mex67p

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Interactions

    General gene information

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables FMN binding  
    enables NADPH dehydrogenase activity  
    enables NADPH dehydrogenase activity PubMed 
    enables NADPH dehydrogenase activity  
    enables oxidoreductase activity  
    Component Evidence Code Pubs
    is_active_in cellular_component  

    General protein information

    Preferred Names
    NADPH dehydrogenase
    NP_015154.1
    • Conserved NADPH oxidoreductase containing flavin mononucleotide (FMN); homologous to Oye2p with different ligand binding and catalytic properties; has potential roles in oxidative stress response and programmed cell death

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001148.4 Reference assembly

      Range
      226169..227371 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001183985.1 → NP_015154.1  TPA: NADPH dehydrogenase [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_015154.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W3J7, E9P937, P41816
      UniProtKB/TrEMBL
      A6ZW82, B3LKQ7, B5VT01, C7GJC2, C8ZIK7, N1P1D3
      Conserved Domains (1) summary
      cd02933
      Location:16 → 372
      OYE_like_FMN; Old yellow enzyme (OYE)-like FMN binding domain. OYE was the first flavin-dependent enzyme identified, however its true physiological role remains elusive to this day. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a ...
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