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    ARP8 Arp8p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 854309, updated on 4-Jan-2025

    Summary

    Official Symbol
    ARP8
    Official Full Name
    Arp8p
    Primary source
    SGD:S000005667
    Locus tag
    YOR141C
    See related
    AllianceGenome:SGD:S000005667; FungiDB:YOR141C; VEuPathDB:YOR141C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Enables mRNA binding activity. Involved in chromatin remodeling; double-strand break repair; and mitotic recombination. Located in nucleus. Part of Ino80 complex. Orthologous to human ACTR8 (actin related protein 8). [provided by Alliance of Genome Resources, Jan 2025]
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    Genomic context

    See ARP8 in Genome Data Viewer
    Location:
    chromosome: XV
    Exon count:
    1
    Sequence:
    Chromosome: XV; NC_001147.6 (589942..592587, complement)

    Chromosome XV - NC_001147.6Genomic Context describing neighboring genes Neighboring gene Rup1p Neighboring gene Sfl1p Neighboring gene succinate--CoA ligase (GDP-forming) subunit alpha Neighboring gene tRNA-Gly

    Bibliography

    Interactions

    General gene information

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables ATP binding  
    enables mRNA binding PubMed 
    Process Evidence Code Pubs
    involved_in DNA damage response PubMed 
    involved_in chromatin remodeling PubMed 
    involved_in double-strand break repair  
    involved_in double-strand break repair PubMed 
    involved_in mitotic recombination PubMed 
    involved_in regulation of DNA-templated transcription  
    Component Evidence Code Pubs
    part_of Ino80 complex  
    part_of Ino80 complex PubMed 
    located_in cytoplasm  
    located_in cytoskeleton  
    located_in intracellular membraneless organelle  
    located_in nucleus PubMed 
    located_in nucleus  

    General protein information

    Preferred Names
    Arp8p
    NP_014784.1
    • Nuclear actin-related protein involved in chromatin remodeling; component of chromatin-remodeling enzyme complexes; has mRNA binding activity

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001147.6 Reference assembly

      Range
      589942..592587 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001183560.1 → NP_014784.1  TPA: Arp8p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_014784.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W2J7, Q12386
      UniProtKB/TrEMBL
      G2WN14
      Conserved Domains (2) summary
      smart00268
      Location:266 → 878
      ACTIN; Actin
      cl17037
      Location:42 → 447
      NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily
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