U.S. flag

An official website of the United States government

Links from GEO Profiles

    • Showing Current items.

    ARP4 Arp4p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 853364, updated on 9-Dec-2024

    Summary

    Official Symbol
    ARP4
    Official Full Name
    Arp4p
    Primary source
    SGD:S000003617
    Locus tag
    YJL081C
    See related
    AllianceGenome:SGD:S000003617; FungiDB:YJL081C; VEuPathDB:YJL081C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    ACT3
    Summary
    Enables ATP binding activity; chromatin binding activity; and histone binding activity. Involved in several processes, including DNA repair; kinetochore assembly; and regulation of transcription by RNA polymerase II. Located in chromatin and nucleus. Part of Ino80 complex; NuA4 histone acetyltransferase complex; and Swr1 complex. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 76. Orthologous to several human genes including ACTL6B (actin like 6B). [provided by Alliance of Genome Resources, Dec 2024]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See ARP4 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    1
    Sequence:
    Chromosome: X; NC_001142.9 (283802..285271, complement)

    Chromosome X - NC_001142.9Genomic Context describing neighboring genes Neighboring gene Tax4p Neighboring gene Iml2p Neighboring gene Scp160p Neighboring gene sterol-binding protein

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Interactions

    General gene information

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables ATP binding PubMed 
    enables chromatin binding  
    enables chromatin binding PubMed 
    enables histone binding PubMed 
    Process Evidence Code Pubs
    involved_in DNA repair PubMed 
    involved_in DNA repair  
    involved_in DNA repair PubMed 
    involved_in chromatin organization  
    involved_in chromatin organization PubMed 
    involved_in chromatin remodeling  
    involved_in chromatin remodeling PubMed 
    involved_in kinetochore assembly PubMed 
    involved_in regulation of DNA-templated transcription PubMed 
    involved_in regulation of transcription by RNA polymerase II  
    involved_in regulation of transcription by RNA polymerase II PubMed 
    Component Evidence Code Pubs
    part_of Ino80 complex PubMed 
    part_of NuA4 histone acetyltransferase complex  
    part_of NuA4 histone acetyltransferase complex PubMed 
    part_of SWI/SNF complex  
    part_of Swr1 complex PubMed 
    located_in chromatin PubMed 
    located_in intracellular membraneless organelle  
    located_in nucleus PubMed 
    located_in nucleus  

    General protein information

    Preferred Names
    Arp4p
    NP_012454.1
    • Nuclear actin-related protein involved in chromatin remodeling; component of chromatin-remodeling enzyme complexes

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001142.9 Reference assembly

      Range
      283802..285271 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001181514.1 → NP_012454.1  TPA: Arp4p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_012454.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VWA2, P80428
      UniProtKB/TrEMBL
      A6ZPP3, B3LQ31, C7GR32, C8ZB79, G2WGT6, N1P193
      Conserved Domains (1) summary
      COG5277
      Location:9 → 488
      COG5277; Actin-related protein [Cytoskeleton]
    External link. Please review our privacy policy.