U.S. flag

An official website of the United States government

Links from GEO Profiles

    • Showing Current items.

    Chd64 Chd64 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 38490, updated on 4-Jan-2025

    Summary

    Official Symbol
    Chd64provided by FlyBase
    Official Full Name
    Chd64provided by FlyBase
    Primary source
    FLYBASE:FBgn0035499
    Locus tag
    Dmel_CG14996
    See related
    AllianceGenome:FB:FBgn0035499
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    anon-EST:Liang-1.80; CG-14996; CG14996; clone 1.80; CT34849; Dmel\CG14996
    Summary
    Enables juvenile hormone response element binding activity. Involved in juvenile hormone mediated signaling pathway. Predicted to be located in striated muscle thin filament. Predicted to be active in actin cytoskeleton. Is expressed in several structures, including Malpighian tubule primordium; embryonic/larval midgut primordium; epithelium; germline cell; and gut section. Orthologous to human TAGLN (transgelin); TAGLN2 (transgelin 2); and TAGLN3 (transgelin 3). [provided by Alliance of Genome Resources, Jan 2025]
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Chd64 in Genome Data Viewer
    Location:
    64A6-64A7; 3-10 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (4114289..4122388, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (4114289..4122388, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR45670 Neighboring gene Activated Cdc42 kinase Neighboring gene ensconsin Neighboring gene Replication factor C subunit 4

    Genomic regions, transcripts, and products

    Interactions

    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables actin filament binding  
    enables juvenile hormone response element binding PubMed 
    enables protein binding PubMed 
    Process Evidence Code Pubs
    involved_in actin filament organization  
    involved_in juvenile hormone mediated signaling pathway PubMed 
    involved_in smooth muscle contraction PubMed 
    Component Evidence Code Pubs
    is_active_in actin cytoskeleton  
    located_in striated muscle thin filament PubMed 

    General protein information

    Preferred Names
    Chd64
    Names
    CG14996-PB
    CG14996-PC
    Chd64-PB
    Chd64-PC

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      4114289..4122388 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_139603.3 → NP_647860.1  Chd64, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_647860.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9NHZ2, Q9VZI1
      Related
      FBpp0073126
      Conserved Domains (2) summary
      pfam00402
      Location:165 → 187
      Calponin; Calponin family repeat
      cl00030
      Location:22 → 131
      CH_SF; calponin homology (CH) domain superfamily
    2. NM_001274469.1 → NP_001261398.1  Chd64, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001261398.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9PE30
      Conserved Domains (2) summary
      pfam00402
      Location:152 → 174
      Calponin; Calponin family repeat
      cl00030
      Location:9 → 118
      CH_SF; calponin homology (CH) domain superfamily
    External link. Please review our privacy policy.