|
| Status |
Public on Jan 01, 2021 |
| Title |
Kynurenine treatment of herpesivrus stimulated iCD103 dendritic cells |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
We report the gene expression (obtained by next generation RNAseq) of inducible CD103+ dendritic cells, iCD103 cells, stimulated with both murine herpesvirus-68 and the immunomodulatory tryptophan derivative kynurenine (kyn). This study provides data on how tryptophan derivatives can modulate pro-inflammatory cytokine expression in virus treated dendritic cells.
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| |
|
| Overall design |
iCD103+ DCs were treated with γHV-68 w/ or w/o co-incubation with kyn. Cells treated with a DMSO vehicle serve as control.
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| |
|
| Contributor(s) |
Gurczynski SJ, Moore BB |
| Citation(s) |
33491663 |
| |
| Submission date |
Oct 28, 2020 |
| Last update date |
Mar 16, 2021 |
| Contact name |
Stephen J. Gurczynski |
| E-mail(s) |
[email protected]
|
| Phone |
734-647-9968
|
| Organization name |
University Of Michigan
|
| Department |
Internal Medicine
|
| Lab |
Moore
|
| Street address |
109 Zina Pitcher Pl, Room 4062
|
| City |
Ann Arbor |
| State/province |
MI |
| ZIP/Postal code |
48109 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL13112 |
Illumina HiSeq 2000 (Mus musculus) |
|
| Samples (12)
|
|
| Relations |
| BioProject |
PRJNA672924 |
| SRA |
SRP289471 |
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