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Series GSE28819 Query DataSets for GSE28819
Status Public on Sep 30, 2011
Title Changes in the Bone Marrow Microenvironment Impact Anabolic Actions of PTH
Organism Mus musculus
Experiment type Expression profiling by array
Summary Irradiation induced bone marrow ablation ultimately enhanced PTH anabolic effects in bone.
B6 mice at 10 days of age were sub-lethally irradiated and treated with PTH 24h later for 5 days. 24h post last-injection, bone marrow was flushed with Trizol and RNA isolated and purified. Microarray analyses was performed to determine differential differences in PTH effects in non-irradiated vs. irradiated bone marrow.
 
Overall design Triplicates of 4 groups (total of 12 samples) which include: Nonirradiated Vehicle, Nonirradiated PTH, Irradiated Vehicle and Irradiated PTH
 
Contributor(s) McCauley LK, Koh AJ
Citation(s) 22045660
Submission date Apr 24, 2011
Last update date Mar 04, 2019
Contact name Amy J Koh
Organization name University of Michigan
Department POM
Lab Laurie K. McCauley
Street address 1011 N. University Ave.
City Ann Arbor
State/province MI
ZIP/Postal code 48109
Country USA
 
Platforms (1)
GPL6246 [MoGene-1_0-st] Affymetrix Mouse Gene 1.0 ST Array [transcript (gene) version]
Samples (12)
GSM713688 whole bone marrow-nonirradiated-vehicle-rep1
GSM713689 whole bone marrow-nonirradiated-vehicle-rep2
GSM713690 whole bone marrow-nonirradiated-vehicle-rep3
Relations
BioProject PRJNA138773

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE28819_RAW.tar 48.7 Mb (http)(custom) TAR (of CEL)
Processed data included within Sample table

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