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Series GSE53196 Query DataSets for GSE53196
Status Public on Dec 11, 2013
Title Expression data from drosophila melanogaster
Organism Drosophila melanogaster
Experiment type Expression profiling by array
Summary Space travel presents unlimited opportunities for exploration and discovery, but requires a more complete understanding of the immunological consequences of long-term exposure to the conditions of spaceflight. To understand these consequences better and to contribute to design of effective countermeasures, we used the Drosophila model to compare innate immune responses to bacteria and fungi in flies that were either raised on earth or in outer space aboard the NASA Space Shuttle Discovery (STS-121).
Microarrays were used to characterize changes in gene expression that occur in response to infection by bacteria and fungus in drosophila that were either hatched and raised in outer space (microgravity) or on earth (normal gravity).
 
Overall design Whole Oregon R strain drosophila melanogaster fruit flies either raised on earth or in space that were (1) uninfected, (2) infected with bacteria (Escherichia coli), or (3) infected with fungus (Beauveria bassiana) were used for RNA extraction and hybridization on Affymetrix microarrays.
 
Contributor(s) George MD
Citation(s) 24475130
Submission date Dec 10, 2013
Last update date Oct 23, 2019
Contact name Michael George
E-mail(s) [email protected]
Organization name University of California, Davis
Department Medical Microbiology and Immunology
Street address 451 Health Sciences Drive
City Davis
State/province CA
ZIP/Postal code 95616
Country USA
 
Platforms (1)
GPL1322 [Drosophila_2] Affymetrix Drosophila Genome 2.0 Array
Samples (18)
GSM1287094 Whole fly tissue: hatched and raised in microgravity uninfected biological rep 1
GSM1287095 Whole fly tissue: hatched and raised in microgravity uninfected biological rep 2
GSM1287096 Whole fly tissue: hatched and raised in microgravity uninfected biological rep 3
Relations
BioProject PRJNA231083

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE53196_RAW.tar 38.3 Mb (http)(custom) TAR (of CEL)
Processed data included within Sample table
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