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Series GSE74821 Query DataSets for GSE74821
Status Public on Nov 10, 2015
Title Gene expression analysis of CALGB 9741 patient tumor samples using the nCounter RUO-PAM50 signature
Organism Homo sapiens
Experiment type Other
Summary Intrinsic subtyping of breast cancer was performed using an nCounter RUO-PAM50 gene expression assay to determine the ability of instrinsic subtyping to predict what patients may benefit from altered chemotherapy scheduling in the CALGB 9741 clinical trial population.
 
Overall design FFPE primary breast tumor samples archived at the CALGB Pathology Coordinating Office (PCO) were used to obtain total RNA for instrinsic subtyping using the nCounter Analysis System. Gene-expression profiles were generated for 1321 of 1471 patient samples (90%) suitable for inclusion in this study.
 
Contributor(s) Davies SR
Citation(s) 28691057
Liu MC, Pitcher BN, Mardis ER, Davies SR, Friedman PN, Snider JE, Vickery TL, Reed JP, DeSchryver K, Singh B, Gradishar WJ, Perez EA, Martino S, Citron ML, Norton L, Winer EP, Hudis CA, Carey LA, Bernard PS, Nielsen TO, Perou CM, Ellis MJ, Barry WT. PAM50 gene signatures and breast cancer prognosis with adjuvant anthracycline- and taxane-based chemotherapy: correlative analysis of C9741 (Alliance). Npj Breast Cancer 2:15023 (2016) http://dx.doi.org/10.1038/npjbcancer.2015.23
Submission date Nov 09, 2015
Last update date Jul 11, 2019
Contact name Sherri R Davies
E-mail(s) [email protected]
Phone 3147473073
Organization name Washington University
Street address 4950 Parkview Place
City Saint Louis
State/province MO
ZIP/Postal code 63110
Country USA
 
Platforms (1)
GPL21114 NanoString nCounter RUO-PAM50 Gene Expression Custom CodeSet
Samples (1321)
GSM1934697 LGWU101986-1036378WU
GSM1934698 LGWU102547-1036381WU
GSM1934699 LGWU102569-1036382WU
Relations
BioProject PRJNA301606

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE74821_RAW.tar 2.6 Mb (http)(custom) TAR (of RCC)
Processed data included within Sample table
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