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Female Non-Neoplastic Reproductive System Disorder

MedGen UID:: 232506
•Concept ID:: C1333603
•: Disease or Syndrome

Synonym:

Female Non-Neoplastic Reproductive System Disease

Definition

A non-neoplastic disorder that affects the female reproductive system. Representative examples include endometriosis, pelvic inflammatory disease, and endometritis. [from NCI]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVFemale Non-Neoplastic Reproductive System Disorder

Pathological process
- Disease
  - Disorder by Site
    - Disorder of the genitourinary system
      - Reproductive system disorder
        Female reproductive system disorder
        Female Non-Neoplastic Reproductive System Disorder
        Endometriosis
        Atypical Endometriosis
        Cervical endometriosis
        Endometriosis of thorax
        Fallopian tube endometriosis
        Ovarian endometriosis
        Vaginal Endometriosis
        Fallopian Tube Non-Neoplastic Disorder
        Fallopian Tube Metaplastic Papillary Lesion
        Placental Site Nodule and Plaque Occurring in the Fallopian Tube
        Pyosalpinx
        Salpingitis
        Acute salpingitis
        Chronic salpingitis
        Infectious Salpingitis
        Salpingitis isthmica nodosa
        Inhibited female orgasm
        Ovarian Non-Neoplastic Disorder
        Menstrual problem
        Amenorrhea
        Dysmenorrhea
        Early menarche
        Hypomenorrhea
        Irregular menstruation
        Isolated Premature Menarche
        Menorrhagia
        Menstrual molimen
        Oligomenorrhea
        Premature ovarian insufficiency
        ovarian failure
        Acquired Ovarian Failure
        Congenital Ovarian Failure
        Premature ovarian failure
        Ovarian Fibromatosis and Massive Edema
        Ovarian Stromal Hyperplasia
        Ovarian stromal hyperthecosis
        Ovarian torsion
        Polycystic ovaries
        Resistant ovary syndrome
        Pelvic inflammatory disease
        Adnexitis
        Salpingo-oophoritis
        AIDS-Related Pelvic Inflammatory Disease
        Endometritis
        Acute endometritis
        Chronic endometritis
        Post-Abortion Endometritis
        Puerperal endometritis
        Oophoritis
        Parametritis
        Placental Non-Neoplastic Disorder
        Amnionitis
        Chorioamnionitis
        Clinical Chorioamnionitis
        Complete hydatidiform mole
        Low lying placenta
        Partial hydatidiform mole
        Placenta accreta
        Placenta accreta spectrum
        Placenta increta
        Placenta percreta
        Placenta praevia
        Placental abruption
        Placental aromatase deficiency
        Placental infarction
        Acute Placental Infarction
        Remote Placental Infarction
        Subacute Placental Infarction
        Placental Malformation
        Retained placenta
        Uterine Non-Neoplastic Disorder
        Cervical Non-Neoplastic Disorder
        Cervical Atrophy
        Cervical fibroepithelial polyp
        Cervicitis
        Mucous Polyp of Cervix
        Uterine Corpus Non-Neoplastic Disorder
        Endometriosis of uterus
        Uterine prolapse
        Postpartum Uterine Inversion
        Vaginal Non-Neoplastic Disorder
        Atrophy of vagina
        Imperforate Vagina
        Polyp of vagina
        Cyst of Skene duct
        Vaginal fibroepithelial polyp
        Vaginitis
        Atrophic vaginitis
        Bacterial vaginosis
        Infective vaginitis
        Trichomonal vaginitis
        Vulvovaginitis
        Vulvar Non-Neoplastic Disorder
        Polyp of vulva
        Vulva fibroepithelial polyp
        Vulval Infection
        Vulvar dystrophy
        Vulvar lichen sclerosus

Professional guidelines

PubMed

Study of accuracy of colposcopy in VIA and HPV detection-based cervical cancer screening program.

Ghosh I, Mittal S, Banerjee D, Singh P, Dasgupta S, Chatterjee S, Biswas J, Panda C, Basu P
Aust N Z J Obstet Gynaecol 2014 Dec;54(6):570-5. doi: 10.1111/ajo.12282. PMID: 25476810

Long-term complications of lymphoma and its treatment.

Ng AK, LaCasce A, Travis LB
J Clin Oncol 2011 May 10;29(14):1885-92. Epub 2011 Apr 11 doi: 10.1200/JCO.2010.32.8427. PMID: 21483015

Medical treatment of squamous hyperplasia and lichen sclerosus of the vulva.

Zorlu CG, Cobanoglu O
Int J Gynaecol Obstet 1995 Dec;51(3):235-8. doi: 10.1016/0020-7292(95)80012-3. PMID: 8745089

See all (3)

Recent clinical studies

Etiology

Garolla A, Graziani A, Grande G, Ortolani C, Ferlin A
J Endocrinol Invest 2024 Feb;47(2):261-274. Epub 2023 Sep 28 doi: 10.1007/s40618-023-02192-3. PMID: 37770654 Free PMC Article

PTEN promoter methylation and expression in endometrial cancer tissues.

Khatami F, Shahriari S, Aminimoghaddam S, Klashami ZN, Farahani MS, Teimoori-Toolabi L, Amoli MM, Asadi M, Rashidi BH
Epigenomics 2023 Apr;15(8):507-516. Epub 2023 Jun 21 doi: 10.2217/epi-2023-0099. PMID: 37345350

Gonadoblastoma: origin and outcome.

Roth LM, Cheng L
Hum Pathol 2020 Jun;100:47-53. Epub 2019 Dec 2 doi: 10.1016/j.humpath.2019.11.005. PMID: 31805291

Long-term complications of lymphoma and its treatment.

Ng AK, LaCasce A, Travis LB
J Clin Oncol 2011 May 10;29(14):1885-92. Epub 2011 Apr 11 doi: 10.1200/JCO.2010.32.8427. PMID: 21483015

Effect of LHRH agonist, Zoladex, on ovarian histology.

Williamson K, Robertson JF, Ellis IO, Elston CW, Nicholson RI, Blamey RW
Br J Surg 1988 Jun;75(6):595-6. doi: 10.1002/bjs.1800750634. PMID: 2969269

See all (17)

Diagnosis

PTEN promoter methylation and expression in endometrial cancer tissues.

Navigating through perplex morphologic changes after exogenous hormone usage.

Chang RJ, Rivera-Colon G, Chen H, Niu S, Carrick K, Lucas E, Gwin K, Zheng W
Semin Diagn Pathol 2022 May;39(3):148-158. Epub 2021 Oct 28 doi: 10.1053/j.semdp.2021.10.001. PMID: 34782217

Cytopathologic evaluation of patients submitted to radiotherapy for uterine cervix cancer.

Padilha CML, Araújo MLC Junior, Souza SAL
Rev Assoc Med Bras (1992) 2017 Apr;63(4):379-385. doi: 10.1590/1806-9282.63.04.379. PMID: 28614543

Neurologic disorders associated with disease of the ovaries and testis.

Kattah JC, Kattah WC
Handb Clin Neurol 2014;120:787-98. doi: 10.1016/B978-0-7020-4087-0.00052-8. PMID: 24365352

Vulvar cancer.

Canavan TP, Cohen D
Am Fam Physician 2002 Oct 1;66(7):1269-74. PMID: 12387439

See all (25)

Therapy

Garolla A, Graziani A, Grande G, Ortolani C, Ferlin A
J Endocrinol Invest 2024 Feb;47(2):261-274. Epub 2023 Sep 28 doi: 10.1007/s40618-023-02192-3. PMID: 37770654 Free PMC Article

Long-term complications of lymphoma and its treatment.

Ng AK, LaCasce A, Travis LB
J Clin Oncol 2011 May 10;29(14):1885-92. Epub 2011 Apr 11 doi: 10.1200/JCO.2010.32.8427. PMID: 21483015

Vulvar cancer.

Canavan TP, Cohen D
Am Fam Physician 2002 Oct 1;66(7):1269-74. PMID: 12387439

Effect of LHRH agonist, Zoladex, on ovarian histology.

Williamson K, Robertson JF, Ellis IO, Elston CW, Nicholson RI, Blamey RW
Br J Surg 1988 Jun;75(6):595-6. doi: 10.1002/bjs.1800750634. PMID: 2969269

Steroid receptors in normal, hyperplastic and malignant human endometria.

Vihko R, Jänne O, Kauppila A
Ann Clin Res 1980 Oct;12(5):208-15. PMID: 7015983

See all (10)

Prognosis

The efficacy and safety of secondary focused ultrasound therapy for recurrence of non-neoplastic epithelial disorders of the vulva.

Li R, Jiang J
Int J Hyperthermia 2022;39(1):1310-1314. doi: 10.1080/02656736.2022.2131000. PMID: 36202394

Long-term complications of lymphoma and its treatment.

Ng AK, LaCasce A, Travis LB
J Clin Oncol 2011 May 10;29(14):1885-92. Epub 2011 Apr 11 doi: 10.1200/JCO.2010.32.8427. PMID: 21483015

Vulvar cancer.

Canavan TP, Cohen D
Am Fam Physician 2002 Oct 1;66(7):1269-74. PMID: 12387439

Update on the surgical pathology of the vulva.

Johnson TL
Clin Lab Med 1995 Sep;15(3):455-92. PMID: 8542720

Non-neoplastic epithelial disorders of the vulva (vulvar dystrophies): historical and current perspectives.

Lawrence WD
Pathol Annu 1993;28 Pt 2:23-51. PMID: 8395044

See all (16)

Clinical prediction guides

Garolla A, Graziani A, Grande G, Ortolani C, Ferlin A
J Endocrinol Invest 2024 Feb;47(2):261-274. Epub 2023 Sep 28 doi: 10.1007/s40618-023-02192-3. PMID: 37770654 Free PMC Article

PTEN promoter methylation and expression in endometrial cancer tissues.

The efficacy and safety of secondary focused ultrasound therapy for recurrence of non-neoplastic epithelial disorders of the vulva.

Li R, Jiang J
Int J Hyperthermia 2022;39(1):1310-1314. doi: 10.1080/02656736.2022.2131000. PMID: 36202394

Long-term complications of lymphoma and its treatment.

Ng AK, LaCasce A, Travis LB
J Clin Oncol 2011 May 10;29(14):1885-92. Epub 2011 Apr 11 doi: 10.1200/JCO.2010.32.8427. PMID: 21483015

"Mesenchymal tumor" or "decidual-like reaction"?

Karbe E
Toxicol Pathol 1999 May-Jun;27(3):354-62. doi: 10.1177/019262339902700312. PMID: 10356713

See all (18)