U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Ovarian Dermoid Cyst with Secondary Tumor

MedGen UID:
277456
•Concept ID:
C1335156
•
Neoplastic Process
Synonyms: Dermoid Cyst with Secondary Tumor; Somatic Neoplasm Arising from Ovarian Teratoma

Definition

An adult-type tumor that has derived from an ovarian dermoid cyst. Representative examples include dermoid cyst with secondary carcinoma, dermoid cyst with secondary sarcoma, and dermoid cyst with pituitary-type tumor. [from NCI]

Professional guidelines

PubMed

Malignant transformation within ovarian dermoid cysts: an audit of treatment received and patient outcomes. an Australia New Zealand gynaecological oncology group (ANZGOG) and gynaecologic cancer intergroup (GCIG) study.
Gainford MC, Tinker A, Carter J, Petru E, Nicklin J, Quinn M, Hammond I, Elit L, Lenhard M, Friedlander M
Int J Gynecol Cancer 2010 Jan;20(1):75-81. doi: 10.1111/IGC.0b013e3181c7fccf. PMID: 20130506
Ovarian cancer: diagnosis and treatment.
Girtanner R
Compr Ther 1980 May;6(5):30-8. PMID: 7379486

Recent clinical studies

Etiology

Malignant transformation within ovarian dermoid cysts: an audit of treatment received and patient outcomes. an Australia New Zealand gynaecological oncology group (ANZGOG) and gynaecologic cancer intergroup (GCIG) study.
Gainford MC, Tinker A, Carter J, Petru E, Nicklin J, Quinn M, Hammond I, Elit L, Lenhard M, Friedlander M
Int J Gynecol Cancer 2010 Jan;20(1):75-81. doi: 10.1111/IGC.0b013e3181c7fccf. PMID: 20130506
Secondary malignancies in ovarian dermoid cyst.
Al-Rayyan ES, Duqoum WJ, Sawalha MS, Nascimento MC, Pather S, Dalrymple CJ, Carter JR
Saudi Med J 2009 Apr;30(4):524-8. PMID: 19370280
Management and outcomes of adnexal masses during pregnancy: a 6-year experience.
Balci O, Gezginc K, Karatayli R, Acar A, Celik C, Colakoglu MC
J Obstet Gynaecol Res 2008 Aug;34(4):524-8. doi: 10.1111/j.1447-0756.2008.00744.x. PMID: 18946936
Secondary malignant involvement of gynecologic organs in radical cystectomy specimens in women: is it mandatory to remove these organs routinely?
Ali-El-Dein B, Abdel-Latif M, Mosbah A, Eraky I, Shaaban AA, Taha NM, Ghoneim MA
J Urol 2004 Sep;172(3):885-7. doi: 10.1097/01.ju.0000133986.29257.bf. PMID: 15310990
Laparoscopy in adnexal pathology in the child: a study of 28 cases.
Héloury Y, Guiberteau V, Sagot P, Plattner V, Baron M, Rogez JM
Eur J Pediatr Surg 1993 Apr;3(2):75-8. doi: 10.1055/s-2008-1063515. PMID: 8323922

Diagnosis

Malignant transformation of mature cystic teratoma of the ovary.
Atwi D, Kamal M, Quinton M, Hassell LA
J Obstet Gynaecol Res 2022 Dec;48(12):3068-3076. Epub 2022 Sep 2 doi: 10.1111/jog.15409. PMID: 36053141
MR imaging of common and uncommon large pelvic masses.
Szklaruk J, Tamm EP, Choi H, Varavithya V
Radiographics 2003 Mar-Apr;23(2):403-24. doi: 10.1148/rg.232025089. PMID: 12640156
Intralaparoscopic ultrasound and Doppler sonography in urology.
Trombetta C, Liguori G, Savoca G, Siracusano S
Tech Urol 1996 Fall;2(3):165-70. PMID: 9118426
Ovarian cancer: diagnosis and treatment.
Girtanner R
Compr Ther 1980 May;6(5):30-8. PMID: 7379486
Ovarian tumors in children and adolescents.
Breen JL, Maxson WS
Clin Obstet Gynecol 1977 Sep;20(3):607-23. doi: 10.1097/00003081-197709000-00010. PMID: 196802

Therapy

A series of malignant ovarian cancers arising from within a mature cystic teratoma: a single institution experience.
Black JD, Roque DM, Pasternak MC, Buza N, Rutherford TJ, Schwartz PE, McCarthy S, Ratner E
Int J Gynecol Cancer 2015 Jun;25(5):792-7. doi: 10.1097/IGC.0000000000000431. PMID: 25790042
Immature teratoma of the ovary with a minor rhabdomyosarcomatous component and fatal rhabdomyosarcomatous metastases: the first case in a child.
Yanai H, Matsuura H, Kawasaki M, Takada Y, Tabuchi Y, Yoshino T
Int J Gynecol Pathol 2002 Jan;21(1):82-5. doi: 10.1097/00004347-200201000-00016. PMID: 11781530
Ovarian cancer: diagnosis and treatment.
Girtanner R
Compr Ther 1980 May;6(5):30-8. PMID: 7379486
Embryonal cell carcinoma (endodermal sinus type) of the ovary.
Blythe JG, Buchsbaum HJ
Hum Pathol 1973 Dec;4(4):595-9. doi: 10.1016/s0046-8177(73)80068-1. PMID: 4750824
Malignant neural elements in a benign cystic teratoma. A case report.
Shirley RL, Piro AJ, Crocker DW
Obstet Gynecol 1971 Mar;37(3):402-7. PMID: 4323210

Prognosis

Malignant transformation of mature cystic teratoma of the ovary.
Atwi D, Kamal M, Quinton M, Hassell LA
J Obstet Gynaecol Res 2022 Dec;48(12):3068-3076. Epub 2022 Sep 2 doi: 10.1111/jog.15409. PMID: 36053141
Squamous cell carcinoma and osteosarcoma arising from a dermoid cyst--a case report and review of literature.
Allam-Nandyala P, Bui MM, Caracciolo JT, Hakam A
Int J Clin Exp Pathol 2010 Jan 10;3(3):313-8. PMID: 20224730Free PMC Article
Malignant transformation within ovarian dermoid cysts: an audit of treatment received and patient outcomes. an Australia New Zealand gynaecological oncology group (ANZGOG) and gynaecologic cancer intergroup (GCIG) study.
Gainford MC, Tinker A, Carter J, Petru E, Nicklin J, Quinn M, Hammond I, Elit L, Lenhard M, Friedlander M
Int J Gynecol Cancer 2010 Jan;20(1):75-81. doi: 10.1111/IGC.0b013e3181c7fccf. PMID: 20130506
Immature teratoma of the ovary with a minor rhabdomyosarcomatous component and fatal rhabdomyosarcomatous metastases: the first case in a child.
Yanai H, Matsuura H, Kawasaki M, Takada Y, Tabuchi Y, Yoshino T
Int J Gynecol Pathol 2002 Jan;21(1):82-5. doi: 10.1097/00004347-200201000-00016. PMID: 11781530
Squamous cell neoplasms arising from ovarian benign cystic teratoma.
Amérigo J, Nogales FF Jr, Fernandez-Sanz J, Oliva H, Velasco A
Gynecol Oncol 1979 Dec;8(3):277-83. doi: 10.1016/0090-8258(79)90035-0. PMID: 510996

Clinical prediction guides

Malignant transformation of mature cystic teratoma of the ovary.
Atwi D, Kamal M, Quinton M, Hassell LA
J Obstet Gynaecol Res 2022 Dec;48(12):3068-3076. Epub 2022 Sep 2 doi: 10.1111/jog.15409. PMID: 36053141
Extramammary Paget's disease arising in mature cystic teratoma of the ovary.
Shimizu S, Kobayashi H, Suchi T, Torii Y, Narita K, Aoki S
Am J Surg Pathol 1991 Oct;15(10):1002-6. doi: 10.1097/00000478-199110000-00011. PMID: 1718175
Krukenberg tumors of the ovary: a clinicopathologic analysis of 112 cases.
Yakushiji M, Tazaki T, Nishimura H, Kato T
Nihon Sanka Fujinka Gakkai Zasshi 1987 Mar;39(3):479-85. PMID: 3031182
Pathogenesis of teratoid tumors of the ovary and testis.
Mulligan RM
Pathol Annu 1975;10:271-98. PMID: 1101172

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...