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Ovarian teratoma

MedGen UID:: 76072
•Concept ID:: C0280131
•: Neoplastic Process

Synonym:	TERATOMA, OVARIAN
SNOMED CT:	Teratoma of ovary (716077006); Ovarian teratoma (716077006)

HPO:	HP:0012226
Monarch Initiative:	MONDO:0005602
OMIM®:	166950

Definition

The presence of a teratoma in the ovary. [from HPO]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVOvarian teratoma

Neoplasm of the genitourinary tract
- Genital neoplasm
  - Gonadal neoplasm
    - Germ cell neoplasia
      - Teratoma
        Gonadal teratoma
        Ovarian teratoma
        Childhood teratoma of the ovary
        Childhood immature teratoma of ovary
        Childhood mature teratoma of the ovary
        Ovarian biphasic or triphasic teratoma
        Grade 1 Ovarian Teratoma
        Immature ovarian teratoma
        Malignant Ovarian Teratoma
        Mature ovarian teratoma
        Ovarian dermoid cyst
        Ovarian fetiform teratoma
        Ovarian solid teratoma
        Ovarian cystic teratoma
        Ovarian monodermal teratoma
        Ovarian Dermoid Cyst with Secondary Tumor
        Ovarian Dermoid Cyst with Secondary Melanocytic Lesion
        Ovarian Dermoid Cyst with Secondary Pituitary-Type Tumor
        Ovarian Dermoid Cyst with Secondary Sebaceous Tumor
        Ovarian Dermoid Cyst with Somatic-Type Malignancy
        Ovarian monodermal and highly specialized teratoma
        Struma ovarii
        Stage I Ovarian Teratoma AJCC v6 and v7
        Stage II Ovarian Teratoma AJCC v6 and v7
        Stage III Ovarian Teratoma AJCC v6 and v7
        Stage IV Ovarian Teratoma AJCC v6 and v7

Conditions with this feature

Ovarian dermoid cyst

MedGen UID:: 68637
•Concept ID:: C0237020
•: Neoplastic Process

An cystic ovarian teratoma composed of dermal and epidermal elements and containing tissue components including hair, teeth, bone, thyroid, and others.

See: Condition Record

Ovarian dermoid cyst

Professional guidelines

PubMed

Management of immune thrombotic thrombocytopenic purpura without therapeutic plasma exchange.

Kühne L, Knöbl P, Eller K, Thaler J, Sperr WR, Gleixner K, Osterholt T, Kaufeld J, Menne J, Buxhofer-Ausch V, Mühlfeld A, Seelow E, Schreiber A, Todorova P, Cukoski S, Jabs WJ, Özcan F, Gäckler A, Schönfelder K, Seibert FS, Westhoff T, Schwenger V, Eichenauer DA, Völker LA, Brinkkoetter PT
Blood 2024 Oct 3;144(14):1486-1495. doi: 10.1182/blood.2023023780. PMID: 38838300

Early diagnosis and treatment improve outcomes for premenarchal patients with anti-NMDA receptor encephalitis and ovarian teratoma.

French AV, Grossmann L
J Pediatr Adolesc Gynecol 2022 Aug;35(4):516-517. Epub 2022 Mar 28 doi: 10.1016/j.jpag.2022.03.004. PMID: 35358707

Ovarian teratomas: clinical features, imaging findings and management.

Saleh M, Bhosale P, Menias CO, Ramalingam P, Jensen C, Iyer R, Ganeshan D
Abdom Radiol (NY) 2021 Jun;46(6):2293-2307. Epub 2021 Jan 4 doi: 10.1007/s00261-020-02873-0. PMID: 33394097

See all (11)

Recent clinical studies

Etiology

Management of immune thrombotic thrombocytopenic purpura without therapeutic plasma exchange.

Paraneoplastic encephalitis.

Casagrande S, Zuliani L, Grisold W
Handb Clin Neurol 2024;200:131-149. doi: 10.1016/B978-0-12-823912-4.00019-0. PMID: 38494274

Teratoma pathology and genomics in anti-NMDA receptor encephalitis.

Jang Y, Lee K, Lee C, Chu K, Lee SK, Won JK, Lee ST
Ann Clin Transl Neurol 2024 Jan;11(1):225-234. Epub 2023 Nov 21 doi: 10.1002/acn3.51948. PMID: 37986706 Free PMC Article

Benign enhancing components of mature ovarian teratoma: magnetic resonance imaging features and pathologic correlation.

Shin HJ, Kim KA, Kim BH, Lee JK, Park YS, Lee J, Choi JW, Lee CH, Park CM
Clin Imaging 2016 Nov-Dec;40(6):1156-1161. Epub 2016 Aug 5 doi: 10.1016/j.clinimag.2016.08.005. PMID: 27568071

Ovarian teratoma diagnosis and management: case presentations.

Sait K, Simpson C
J Obstet Gynaecol Can 2004 Feb;26(2):137-42. doi: 10.1016/s1701-2163(16)30489-3. PMID: 14965479

See all (168)

Diagnosis

Neoplasms in Struma Ovarii: A Review.

Tondi Resta I, Sande CM, LiVolsi VA
Endocr Pathol 2023 Dec;34(4):455-460. Epub 2023 Oct 21 doi: 10.1007/s12022-023-09789-7. PMID: 37864665

Ovarian teratomas: clinical features, imaging findings and management.

Saleh M, Bhosale P, Menias CO, Ramalingam P, Jensen C, Iyer R, Ganeshan D
Abdom Radiol (NY) 2021 Jun;46(6):2293-2307. Epub 2021 Jan 4 doi: 10.1007/s00261-020-02873-0. PMID: 33394097

An update on anti-NMDA receptor encephalitis for neurologists and psychiatrists: mechanisms and models.

Dalmau J, Armangué T, Planagumà J, Radosevic M, Mannara F, Leypoldt F, Geis C, Lancaster E, Titulaer MJ, Rosenfeld MR, Graus F
Lancet Neurol 2019 Nov;18(11):1045-1057. Epub 2019 Jul 17 doi: 10.1016/S1474-4422(19)30244-3. PMID: 31326280

Encephalitis associated with antibodies against the NMDA receptor.

Guasp M, Dalmau J
Med Clin (Barc) 2018 Jul 23;151(2):71-79. Epub 2017 Nov 26 doi: 10.1016/j.medcli.2017.10.015. PMID: 29183618

Clinical experience and laboratory investigations in patients with anti-NMDAR encephalitis.

Dalmau J, Lancaster E, Martinez-Hernandez E, Rosenfeld MR, Balice-Gordon R
Lancet Neurol 2011 Jan;10(1):63-74. doi: 10.1016/S1474-4422(10)70253-2. PMID: 21163445 Free PMC Article

See all (458)

Therapy

Management of immune thrombotic thrombocytopenic purpura without therapeutic plasma exchange.

An update on anti-NMDA receptor encephalitis for neurologists and psychiatrists: mechanisms and models.

Not hysteria: ovarian teratoma-associated anti-N-methyl-D-aspartate receptor encephalitis.

Roberts R, MacDougall NJ, O'Brien P, Abdelaziz K, Christie J, Swingler R
Scott Med J 2012 Aug;57(3):182. doi: 10.1258/smj.2012.012026. PMID: 22859813

Clinical experience and laboratory investigations in patients with anti-NMDAR encephalitis.

Dalmau J, Lancaster E, Martinez-Hernandez E, Rosenfeld MR, Balice-Gordon R
Lancet Neurol 2011 Jan;10(1):63-74. doi: 10.1016/S1474-4422(10)70253-2. PMID: 21163445 Free PMC Article

Paraneoplastic anti-N-methyl-D-aspartate receptor encephalitis associated with ovarian teratoma.

Dalmau J, Tüzün E, Wu HY, Masjuan J, Rossi JE, Voloschin A, Baehring JM, Shimazaki H, Koide R, King D, Mason W, Sansing LH, Dichter MA, Rosenfeld MR, Lynch DR
Ann Neurol 2007 Jan;61(1):25-36. doi: 10.1002/ana.21050. PMID: 17262855 Free PMC Article

See all (108)

Prognosis

Paraneoplastic encephalitis.

Casagrande S, Zuliani L, Grisold W
Handb Clin Neurol 2024;200:131-149. doi: 10.1016/B978-0-12-823912-4.00019-0. PMID: 38494274

An update on anti-NMDA receptor encephalitis for neurologists and psychiatrists: mechanisms and models.

Encephalitis associated with antibodies against the NMDA receptor.

Guasp M, Dalmau J
Med Clin (Barc) 2018 Jul 23;151(2):71-79. Epub 2017 Nov 26 doi: 10.1016/j.medcli.2017.10.015. PMID: 29183618

Anti-NMDAR autoimmune encephalitis.

Miya K, Takahashi Y, Mori H
Brain Dev 2014 Sep;36(8):645-52. Epub 2013 Nov 5 doi: 10.1016/j.braindev.2013.10.005. PMID: 24211006

Paraneoplastic neurological syndromes.

Graus F, Dalmau J
Curr Opin Neurol 2012 Dec;25(6):795-801. doi: 10.1097/WCO.0b013e328359da15. PMID: 23041955 Free PMC Article

See all (219)

Clinical prediction guides

Anti-N-methyl-D-aspartate receptor encephalitis after coronavirus disease 2019: A case report and literature review.

Lee H, Jeon JH, Choi H, Koh SH, Lee KY, Lee YJ, Kwon HS
Medicine (Baltimore) 2022 Sep 2;101(35):e30464. doi: 10.1097/MD.0000000000030464. PMID: 36107550 Free PMC Article

Encephalitis associated with antibodies against the NMDA receptor.

Guasp M, Dalmau J
Med Clin (Barc) 2018 Jul 23;151(2):71-79. Epub 2017 Nov 26 doi: 10.1016/j.medcli.2017.10.015. PMID: 29183618

Glial fibrillary acidic protein immunoglobulin G as biomarker of autoimmune astrocytopathy: Analysis of 102 patients.

Flanagan EP, Hinson SR, Lennon VA, Fang B, Aksamit AJ, Morris PP, Basal E, Honorat JA, Alfugham NB, Linnoila JJ, Weinshenker BG, Pittock SJ, McKeon A
Ann Neurol 2017 Feb;81(2):298-309. doi: 10.1002/ana.24881. PMID: 28120349

Autoimmune Encephalitis in Postpartum Psychosis.

Bergink V, Armangue T, Titulaer MJ, Markx S, Dalmau J, Kushner SA
Am J Psychiatry 2015 Sep 1;172(9):901-8. Epub 2015 Jul 17 doi: 10.1176/appi.ajp.2015.14101332. PMID: 26183699 Free PMC Article

Paraneoplastic neurological syndromes.

Graus F, Dalmau J
Curr Opin Neurol 2012 Dec;25(6):795-801. doi: 10.1097/WCO.0b013e328359da15. PMID: 23041955 Free PMC Article

See all (117)

Recent systematic reviews

Possible temporal relationship between SARS-CoV-2 infection and anti-NMDA receptor encephalitis: a meta-analysis.

Vasilevska V, Guest PC, Szardenings M, Benros ME, Steiner J
Transl Psychiatry 2024 Mar 8;14(1):139. doi: 10.1038/s41398-024-02831-0. PMID: 38459000 Free PMC Article

Effect and timing of operative treatment for teratoma associated N-Methyl-d-Aspartate receptor-antibody encephalitis: A systematic review with meta-analysis.

Erlebach R, Brandi G
J Neuroimmunol 2023 Sep 15;382:578153. Epub 2023 Jul 22 doi: 10.1016/j.jneuroim.2023.578153. PMID: 37499300

Prevalence of metachronous contralateral mature ovarian teratoma: A systematic review.

Kiely D, Lewis C, Gray J, Hall N
Pediatr Blood Cancer 2021 Nov;68(11):e29237. Epub 2021 Jul 31 doi: 10.1002/pbc.29237. PMID: 34331503

Extragonadal teratomas in women and adolescent girls: A systematic review.

Kanneganti A, Bhadiraju P, Tong PSY
Eur J Obstet Gynecol Reprod Biol 2021 Jul;262:134-141. Epub 2021 May 7 doi: 10.1016/j.ejogrb.2021.05.005. PMID: 34022590

Ovarian teratoma-associated anti-NMDAR encephalitis: a systematic review of reported cases.

Acién P, Acién M, Ruiz-Maciá E, Martín-Estefanía C
Orphanet J Rare Dis 2014 Oct 14;9:157. doi: 10.1186/s13023-014-0157-x. PMID: 25312434 Free PMC Article

See all (11)

MedGen

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Ovarian teratoma

Definition

Term Hierarchy

Conditions with this feature

Professional guidelines

PubMed

Recent clinical studies

Etiology

Diagnosis

Therapy

Prognosis

Clinical prediction guides

Recent systematic reviews

Supplemental Content

Table of contents

Clinical resources

Practice guidelines

Consumer resources

Reviews

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