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Malignant germ cell tumor of ovary

MedGen UID:
87544
•Concept ID:
C0346180
•
Neoplastic Process
Synonym: Ovarian germ cell cancer
SNOMED CT: Malignant germ cell tumor of ovary (254869000)
Modes of inheritance:
Unknown inheritance
MedGen UID:
989040
•Concept ID:
CN307042
•
Finding
Source: Orphanet
Hereditary clinical entity whose mode of inheritance is unknown.
See: This record
Unknown inheritance (Orphanet)
 
Monarch Initiative: MONDO:0018171
OMIM®: 603737
Orphanet: ORPHA35807

Definition

Ovarian germ cell cancers are malignancies that arise from germ cells of the embryonic gonad. Although benign germ cell tumors are relatively common, accounting for approximately 20% of all ovarian neoplasms, malignant ovarian germ cell tumors are rare. Weiss et al. (1977) estimated that less than 5% of ovarian cancers are of germ cell origin. [from OMIM]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMalignant germ cell tumor of ovary
Follow this link to review classifications for Malignant germ cell tumor of ovary in Orphanet.

Professional guidelines

PubMed

ESGO-SIOPE guidelines for the management of adolescents and young adults with non-epithelial ovarian cancers.
Sessa C, Schneider DT, Planchamp F, Baust K, Braicu EI, Concin N, Godzinski J, McCluggage WG, Orbach D, Pautier P, Peccatori FA, Morice P, Calaminus G
Lancet Oncol 2020 Jul;21(7):e360-e368. doi: 10.1016/S1470-2045(20)30091-7. PMID: 32615119
Non-epithelial ovarian cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up.
Ray-Coquard I, Morice P, Lorusso D, Prat J, Oaknin A, Pautier P, Colombo N; ESMO Guidelines Committee
Ann Oncol 2018 Oct 1;29(Suppl 4):iv1-iv18. doi: 10.1093/annonc/mdy001. PMID: 29697741
The diagnosis and treatment of yolk sac tumors in infants and children.
Green DM
Cancer Treat Rev 1983 Dec;10(4):265-88. doi: 10.1016/0305-7372(83)90014-2. PMID: 6362873

Curated

NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®), Ovarian Cancer Including Fallopian Tube Cancer and Primary Peritoneal Cancer, 2024

UK NICE Clinical guideline (CG122), Ovarian cancer: recognition and initial management, 2023

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Curated

    • NCCN, 2024
      NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®), Ovarian Cancer Including Fallopian Tube Cancer and Primary Peritoneal Cancer, 2024
    • NICE, 2023
      UK NICE Clinical guideline (CG122), Ovarian cancer: recognition and initial management, 2023

    Reviews

    Related information

    • ClinVar
      Related medical variations
    • MeSH
      Related Medical Subject Headings
    • OMIM
      Related records in OMIM
    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed
    • PubMed (OMIM)
      Related literature resources in PubMed

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