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Intestinal benign neoplasm

MedGen UID:
91124
•Concept ID:
C0347269
•
Neoplastic Process
Synonyms: Benign Intestinal Neoplasm; benign intestinal neoplasm; Benign Intestinal Neoplasms; benign intestinal neoplasms; Benign Intestinal Tumor; benign intestinal tumor; Benign Intestinal Tumors; benign intestinal tumors; benign intestinal tumour; benign intestinal tumours; Benign Intestine Neoplasm; benign intestine neoplasm; Benign Intestine Tumor; benign intestine tumor; benign intestine tumour; Benign neoplasm of intestinal tract; Benign neoplasm of intestine; Benign Neoplasm of Intestines; benign neoplasm of intestines; Benign Neoplasm of the Intestines; benign neoplasm of the intestines; Benign Neoplasms of Large and/or Small Intestine; benign neoplasms of large and/or small intestine; Benign Neoplasms of the Large and/or Small Intestine; benign neoplasms of the large and/or small intestine; Benign tumor of intestine; Benign Tumor of Intestines; benign tumor of intestines; Benign Tumor of the Intestines; benign tumor of the intestines; benign tumour of intestines; benign tumour of the intestines; intestinal benign neoplasm; Intestinal Neoplasms, Benign; intestinal neoplasms, benign; Intestinal Tumors, Benign; intestinal tumors, benign; intestine benign neoplasm
SNOMED CT: Benign neoplasm of intestinal tract (92151003); Benign neoplasm of intestine (92151003); Benign tumor of intestine (92151003)
 
Monarch Initiative: MONDO:0003062

Definition

A neoplasm that arises from the small or large intestine and is characterized by the absence of atypical or malignant cytological and architectural features, and absence of invasive features or metastatic potential. [from NCI]

Professional guidelines

PubMed

AGA Clinical Practice Guidelines on Management of Gastric Intestinal Metaplasia.
Gupta S, Li D, El Serag HB, Davitkov P, Altayar O, Sultan S, Falck-Ytter Y, Mustafa RA
Gastroenterology 2020 Feb;158(3):693-702. Epub 2019 Dec 6 doi: 10.1053/j.gastro.2019.12.003. PMID: 31816298Free PMC Article
Appendiceal Mucinous Neoplasms: Diagnosis and Management.
Shaib WL, Assi R, Shamseddine A, Alese OB, Staley C 3rd, Memis B, Adsay V, Bekaii-Saab T, El-Rayes BF
Oncologist 2017 Sep;22(9):1107-1116. Epub 2017 Jun 29 doi: 10.1634/theoncologist.2017-0081. PMID: 28663356Free PMC Article
ACG clinical guideline: Genetic testing and management of hereditary gastrointestinal cancer syndromes.
Syngal S, Brand RE, Church JM, Giardiello FM, Hampel HL, Burt RW; American College of Gastroenterology
Am J Gastroenterol 2015 Feb;110(2):223-62; quiz 263. Epub 2015 Feb 3 doi: 10.1038/ajg.2014.435. PMID: 25645574Free PMC Article

Recent clinical studies

Etiology

Updates in the diagnosis and management of small-bowel tumors.
Vlachou E, Koffas A, Toumpanakis C, Keuchel M
Best Pract Res Clin Gastroenterol 2023 Jun-Aug;64-65:101860. Epub 2023 Aug 12 doi: 10.1016/j.bpg.2023.101860. PMID: 37652650
The Small Bowel Cancer Incidence Enigma.
Assumpção P, Khayat A, Araújo T, Barra W, Ishak G, Cruz A, Santos S, Santos Â, Demachki S, Assumpção P, Calcagno D, Santos N, Assumpção M, Moreira F, Santos A, Assumpção C, Riggins G, Burbano R
Pathol Oncol Res 2020 Apr;26(2):635-639. Epub 2019 Jun 5 doi: 10.1007/s12253-019-00682-5. PMID: 31165996
Minimally Invasive Small Bowel Cancer Surgery.
Baiu I, Visser BC
Surg Oncol Clin N Am 2019 Apr;28(2):273-283. Epub 2018 Dec 24 doi: 10.1016/j.soc.2018.11.008. PMID: 30851828
The pathogenesis of constipation.
Sykes NP
J Support Oncol 2006 May;4(5):213-8. PMID: 16724641
Inflammatory bowel disease.
Schölmerich J
Endoscopy 1999 Jan;31(1):66-73. doi: 10.1055/s-1999-13650. PMID: 10082412

Diagnosis

Small-Bowel Neuroendocrine Tumors.
Galbraith NJ, Sokas CM
Dis Colon Rectum 2024 Aug 1;67(8):997-1000. Epub 2024 Jul 13 doi: 10.1097/DCR.0000000000003387. PMID: 38752658
Updates in the diagnosis and management of small-bowel tumors.
Vlachou E, Koffas A, Toumpanakis C, Keuchel M
Best Pract Res Clin Gastroenterol 2023 Jun-Aug;64-65:101860. Epub 2023 Aug 12 doi: 10.1016/j.bpg.2023.101860. PMID: 37652650
Hierarchy and Plasticity in the Intestinal Stem Cell Compartment.
Yousefi M, Li L, Lengner CJ
Trends Cell Biol 2017 Oct;27(10):753-764. Epub 2017 Jul 18 doi: 10.1016/j.tcb.2017.06.006. PMID: 28732600Free PMC Article
Inflammatory bowel disease.
Schölmerich J
Endoscopy 1999 Jan;31(1):66-73. doi: 10.1055/s-1999-13650. PMID: 10082412
Peritoneal endosalpingiosis.
Clausen I
Zentralbl Gynakol 1991;113(6):329-32. PMID: 2058343

Therapy

ECOG-ACRIN Guideline for Contouring and Treatment of Early Stage Anal Cancer Using IMRT/IGRT.
Damico N, Meyer J, Das P, Murphy J, Miller E, Koontz B, Hall W, McBride M, Pereira G, Catalano P, Chakravarthy AB, O'Dwyer PJ, Dorth J
Pract Radiat Oncol 2022 Jul-Aug;12(4):335-347. doi: 10.1016/j.prro.2022.01.015. PMID: 35717050
Microalgae-based oral microcarriers for gut microbiota homeostasis and intestinal protection in cancer radiotherapy.
Zhang D, Zhong D, Ouyang J, He J, Qi Y, Chen W, Zhang X, Tao W, Zhou M
Nat Commun 2022 Mar 17;13(1):1413. doi: 10.1038/s41467-022-28744-4. PMID: 35301299Free PMC Article
STAT signaling in the intestine.
Nobel YR, Stier K, Krishnareddy S
Int Rev Cell Mol Biol 2021;361:1-20. Epub 2021 May 13 doi: 10.1016/bs.ircmb.2021.02.001. PMID: 34074491
Understanding short bowel syndrome: Current status and future perspectives.
Massironi S, Cavalcoli F, Rausa E, Invernizzi P, Braga M, Vecchi M
Dig Liver Dis 2020 Mar;52(3):253-261. Epub 2019 Dec 28 doi: 10.1016/j.dld.2019.11.013. PMID: 31892505
Nickel and human health.
Zambelli B, Ciurli S
Met Ions Life Sci 2013;13:321-57. doi: 10.1007/978-94-007-7500-8_10. PMID: 24470096

Prognosis

Wnt Signaling in 3D: Recent Advances in the Applications of Intestinal Organoids.
Merenda A, Fenderico N, Maurice MM
Trends Cell Biol 2020 Jan;30(1):60-73. Epub 2019 Nov 9 doi: 10.1016/j.tcb.2019.10.003. PMID: 31718893
The Small Bowel Cancer Incidence Enigma.
Assumpção P, Khayat A, Araújo T, Barra W, Ishak G, Cruz A, Santos S, Santos Â, Demachki S, Assumpção P, Calcagno D, Santos N, Assumpção M, Moreira F, Santos A, Assumpção C, Riggins G, Burbano R
Pathol Oncol Res 2020 Apr;26(2):635-639. Epub 2019 Jun 5 doi: 10.1007/s12253-019-00682-5. PMID: 31165996
Small bowel tumors and polyposis syndromes.
Rossini FP, Risio M, Pennazio M
Gastrointest Endosc Clin N Am 1999 Jan;9(1):93-114. PMID: 9834319
Duodenal villous tumors.
Bjork KJ, Davis CJ, Nagorney DM, Mucha P Jr
Arch Surg 1990 Aug;125(8):961-5. doi: 10.1001/archsurg.1990.01410200019001. PMID: 2378560
PANCREATODUODENECTOMY.
BUCKWALTER JA, LAWTON RI, TIDRICK RT
Arch Surg 1964 Aug;89:331-9. doi: 10.1001/archsurg.1964.01320020095015. PMID: 14160161

Clinical prediction guides

The epigenetic landscape in intestinal stem cells and its deregulation in colorectal cancer.
Larue AEM, Atlasi Y
Stem Cells 2024 Jun 14;42(6):509-525. doi: 10.1093/stmcls/sxae027. PMID: 38597726Free PMC Article
Volvulus of the Appendix.
Bhojwani D, Gourgiotis S, Simillis C
Gastroenterology 2021 Dec;161(6):1809-1810. Epub 2021 Aug 27 doi: 10.1053/j.gastro.2021.08.038. PMID: 34461051
Wnt Signaling in 3D: Recent Advances in the Applications of Intestinal Organoids.
Merenda A, Fenderico N, Maurice MM
Trends Cell Biol 2020 Jan;30(1):60-73. Epub 2019 Nov 9 doi: 10.1016/j.tcb.2019.10.003. PMID: 31718893
Role of capsule endoscopy in inflammatory bowel disease.
Kopylov U, Seidman EG
World J Gastroenterol 2014 Feb 7;20(5):1155-64. doi: 10.3748/wjg.v20.i5.1155. PMID: 24574792Free PMC Article
Enteroscopy.
Mönkemüller K, Bellutti M, Fry LC, Malfertheiner P
Best Pract Res Clin Gastroenterol 2008;22(5):789-811. doi: 10.1016/j.bpg.2008.05.005. PMID: 18790433

Recent systematic reviews

Gastrointestinal Stromal Tumours (GIST) of the Rectum: A Systematic Review and Meta-Analysis.
Khan SI, O'Sullivan NJ, Temperley HC, Rausa E, Mehigan BJ, McCormick P, Larkin JO, Kavanagh DO, Kelly ME
Curr Oncol 2022 Dec 28;30(1):416-429. doi: 10.3390/curroncol30010034. PMID: 36661683Free PMC Article
Total Neoadjuvant Therapy (TNT) versus Standard Neoadjuvant Chemoradiotherapy for Locally Advanced Rectal Cancer: A Systematic Review and Meta-Analysis.
Liu S, Jiang T, Xiao L, Yang S, Liu Q, Gao Y, Chen G, Xiao W
Oncologist 2021 Sep;26(9):e1555-e1566. Epub 2021 Jun 7 doi: 10.1002/onco.13824. PMID: 33987952Free PMC Article
Preventing Colitis-Associated Colon Cancer With Antioxidants: A Systematic Review.
Irrazabal T, Thakur BK, Croitoru K, Martin A
Cell Mol Gastroenterol Hepatol 2021;11(4):1177-1197. Epub 2021 Jan 5 doi: 10.1016/j.jcmgh.2020.12.013. PMID: 33418102Free PMC Article
A Systematic Review of the Clinical Presentation, Diagnosis, and Treatment of Small Bowel Obstruction.
Rami Reddy SR, Cappell MS
Curr Gastroenterol Rep 2017 Jun;19(6):28. doi: 10.1007/s11894-017-0566-9. PMID: 28439845
Lifestyle Risk Factors for Serrated Colorectal Polyps: A Systematic Review and Meta-analysis.
Bailie L, Loughrey MB, Coleman HG
Gastroenterology 2017 Jan;152(1):92-104. Epub 2016 Sep 14 doi: 10.1053/j.gastro.2016.09.003. PMID: 27639804

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