U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Intestinal benign neoplasm

MedGen UID:
91124
•Concept ID:
C0347269
•
Neoplastic Process
Synonyms: Benign Intestinal Neoplasm; benign intestinal neoplasm; Benign Intestinal Neoplasms; benign intestinal neoplasms; Benign Intestinal Tumor; benign intestinal tumor; Benign Intestinal Tumors; benign intestinal tumors; benign intestinal tumour; benign intestinal tumours; Benign Intestine Neoplasm; benign intestine neoplasm; Benign Intestine Tumor; benign intestine tumor; benign intestine tumour; Benign neoplasm of intestinal tract; Benign neoplasm of intestine; Benign Neoplasm of Intestines; benign neoplasm of intestines; Benign Neoplasm of the Intestines; benign neoplasm of the intestines; Benign Neoplasms of Large and/or Small Intestine; benign neoplasms of large and/or small intestine; Benign Neoplasms of the Large and/or Small Intestine; benign neoplasms of the large and/or small intestine; Benign tumor of intestine; Benign Tumor of Intestines; benign tumor of intestines; Benign Tumor of the Intestines; benign tumor of the intestines; benign tumour of intestines; benign tumour of the intestines; intestinal benign neoplasm; Intestinal Neoplasms, Benign; intestinal neoplasms, benign; Intestinal Tumors, Benign; intestinal tumors, benign; intestine benign neoplasm
SNOMED CT: Benign neoplasm of intestinal tract (92151003); Benign neoplasm of intestine (92151003); Benign tumor of intestine (92151003)
 
Monarch Initiative: MONDO:0003062

Definition

A neoplasm that arises from the small or large intestine and is characterized by the absence of atypical or malignant cytological and architectural features, and absence of invasive features or metastatic potential. [from NCI]

Professional guidelines

PubMed

Colorectal Cancer Screening Methods and Molecular Markers for Early Detection.
Wu Z, Li Y, Zhang Y, Hu H, Wu T, Liu S, Chen W, Xie S, Lu Z
Technol Cancer Res Treat 2020 Jan-Dec;19:1533033820980426. doi: 10.1177/1533033820980426. PMID: 33353503Free PMC Article
Appendiceal Mucinous Neoplasms: Diagnosis and Management.
Shaib WL, Assi R, Shamseddine A, Alese OB, Staley C 3rd, Memis B, Adsay V, Bekaii-Saab T, El-Rayes BF
Oncologist 2017 Sep;22(9):1107-1116. Epub 2017 Jun 29 doi: 10.1634/theoncologist.2017-0081. PMID: 28663356Free PMC Article
ACG clinical guideline: Genetic testing and management of hereditary gastrointestinal cancer syndromes.
Syngal S, Brand RE, Church JM, Giardiello FM, Hampel HL, Burt RW; American College of Gastroenterology
Am J Gastroenterol 2015 Feb;110(2):223-62; quiz 263. Epub 2015 Feb 3 doi: 10.1038/ajg.2014.435. PMID: 25645574Free PMC Article

Recent clinical studies

Etiology

Updates in the diagnosis and management of small-bowel tumors.
Vlachou E, Koffas A, Toumpanakis C, Keuchel M
Best Pract Res Clin Gastroenterol 2023 Jun-Aug;64-65:101860. Epub 2023 Aug 12 doi: 10.1016/j.bpg.2023.101860. PMID: 37652650
Minimally Invasive Small Bowel Cancer Surgery.
Baiu I, Visser BC
Surg Oncol Clin N Am 2019 Apr;28(2):273-283. Epub 2018 Dec 24 doi: 10.1016/j.soc.2018.11.008. PMID: 30851828
Small Bowel Neoplasms and Polyps.
Pourmand K, Itzkowitz SH
Curr Gastroenterol Rep 2016 May;18(5):23. doi: 10.1007/s11894-016-0497-x. PMID: 27086004
The pathogenesis of constipation.
Sykes NP
J Support Oncol 2006 May;4(5):213-8. PMID: 16724641
Inflammatory bowel disease.
Schölmerich J
Endoscopy 1999 Jan;31(1):66-73. doi: 10.1055/s-1999-13650. PMID: 10082412

Diagnosis

Updates in the diagnosis and management of small-bowel tumors.
Vlachou E, Koffas A, Toumpanakis C, Keuchel M
Best Pract Res Clin Gastroenterol 2023 Jun-Aug;64-65:101860. Epub 2023 Aug 12 doi: 10.1016/j.bpg.2023.101860. PMID: 37652650
The role of pyroptosis in gastrointestinal cancer and immune responses to intestinal microbial infection.
Zhou CB, Fang JY
Biochim Biophys Acta Rev Cancer 2019 Aug;1872(1):1-10. Epub 2019 May 3 doi: 10.1016/j.bbcan.2019.05.001. PMID: 31059737
Surgical treatment of small bowel neoplasms.
Coco C, Rizzo G, Manno A, Mattana C, Verbo A
Eur Rev Med Pharmacol Sci 2010 Apr;14(4):327-33. PMID: 20496543
Inflammatory bowel disease.
Schölmerich J
Endoscopy 1999 Jan;31(1):66-73. doi: 10.1055/s-1999-13650. PMID: 10082412
Peritoneal endosalpingiosis.
Clausen I
Zentralbl Gynakol 1991;113(6):329-32. PMID: 2058343

Therapy

ECOG-ACRIN Guideline for Contouring and Treatment of Early Stage Anal Cancer Using IMRT/IGRT.
Damico N, Meyer J, Das P, Murphy J, Miller E, Koontz B, Hall W, McBride M, Pereira G, Catalano P, Chakravarthy AB, O'Dwyer PJ, Dorth J
Pract Radiat Oncol 2022 Jul-Aug;12(4):335-347. doi: 10.1016/j.prro.2022.01.015. PMID: 35717050
Microalgae-based oral microcarriers for gut microbiota homeostasis and intestinal protection in cancer radiotherapy.
Zhang D, Zhong D, Ouyang J, He J, Qi Y, Chen W, Zhang X, Tao W, Zhou M
Nat Commun 2022 Mar 17;13(1):1413. doi: 10.1038/s41467-022-28744-4. PMID: 35301299Free PMC Article
Impact of a high‑fat diet on intestinal stem cells and epithelial barrier function in middle‑aged female mice.
Xie Y, Ding F, Di W, Lv Y, Xia F, Sheng Y, Yu J, Ding G
Mol Med Rep 2020 Mar;21(3):1133-1144. Epub 2020 Jan 13 doi: 10.3892/mmr.2020.10932. PMID: 32016468Free PMC Article
Understanding short bowel syndrome: Current status and future perspectives.
Massironi S, Cavalcoli F, Rausa E, Invernizzi P, Braga M, Vecchi M
Dig Liver Dis 2020 Mar;52(3):253-261. Epub 2019 Dec 28 doi: 10.1016/j.dld.2019.11.013. PMID: 31892505
Microbiota and aging.
Bischoff SC
Curr Opin Clin Nutr Metab Care 2016 Jan;19(1):26-30. doi: 10.1097/MCO.0000000000000242. PMID: 26560527

Prognosis

The Small Bowel Cancer Incidence Enigma.
Assumpção P, Khayat A, Araújo T, Barra W, Ishak G, Cruz A, Santos S, Santos Â, Demachki S, Assumpção P, Calcagno D, Santos N, Assumpção M, Moreira F, Santos A, Assumpção C, Riggins G, Burbano R
Pathol Oncol Res 2020 Apr;26(2):635-639. Epub 2019 Jun 5 doi: 10.1007/s12253-019-00682-5. PMID: 31165996
The impact of the intestinal microbiota in therapeutic responses against cancer.
Goubet AG, Daillère R, Routy B, Derosa L, M Roberti P, Zitvogel L
C R Biol 2018 May-Jun;341(5):284-289. Epub 2018 Apr 7 doi: 10.1016/j.crvi.2018.03.004. PMID: 29631891
Large intestine.
Kelly CP
Curr Opin Gastroenterol 2010 Jan;26(1):45-6. doi: 10.1097/MOG.0b013e328333b040. PMID: 19881344
Small intestinal neoplasms.
Gill SS, Heuman DM, Mihas AA
J Clin Gastroenterol 2001 Oct;33(4):267-82. doi: 10.1097/00004836-200110000-00004. PMID: 11588539
Duodenal villous tumors.
Bjork KJ, Davis CJ, Nagorney DM, Mucha P Jr
Arch Surg 1990 Aug;125(8):961-5. doi: 10.1001/archsurg.1990.01410200019001. PMID: 2378560

Clinical prediction guides

Luminally expressed gastrointestinal biomarkers.
Cummins G, Yung DE, Cox BF, Koulaouzidis A, Desmulliez MPY, Cochran S
Expert Rev Gastroenterol Hepatol 2017 Dec;11(12):1119-1134. Epub 2017 Sep 14 doi: 10.1080/17474124.2017.1373017. PMID: 28849686
Clinical implications of intestinal stem cell markers in colorectal cancer.
Espersen ML, Olsen J, Linnemann D, Høgdall E, Troelsen JT
Clin Colorectal Cancer 2015 Jun;14(2):63-71. Epub 2014 Dec 24 doi: 10.1016/j.clcc.2014.12.004. PMID: 25657049
Update on imaging of Peutz-Jeghers syndrome.
Tomas C, Soyer P, Dohan A, Dray X, Boudiaf M, Hoeffel C
World J Gastroenterol 2014 Aug 21;20(31):10864-75. doi: 10.3748/wjg.v20.i31.10864. PMID: 25152588Free PMC Article
Cannabinoids in intestinal inflammation and cancer.
Izzo AA, Camilleri M
Pharmacol Res 2009 Aug;60(2):117-25. Epub 2009 Mar 18 doi: 10.1016/j.phrs.2009.03.008. PMID: 19442536
Enteroscopy.
Mönkemüller K, Bellutti M, Fry LC, Malfertheiner P
Best Pract Res Clin Gastroenterol 2008;22(5):789-811. doi: 10.1016/j.bpg.2008.05.005. PMID: 18790433

Recent systematic reviews

Total Neoadjuvant Therapy (TNT) versus Standard Neoadjuvant Chemoradiotherapy for Locally Advanced Rectal Cancer: A Systematic Review and Meta-Analysis.
Liu S, Jiang T, Xiao L, Yang S, Liu Q, Gao Y, Chen G, Xiao W
Oncologist 2021 Sep;26(9):e1555-e1566. Epub 2021 Jun 7 doi: 10.1002/onco.13824. PMID: 33987952Free PMC Article
Transperineal versus transrectal prostate biopsy in the diagnosis of prostate cancer: a systematic review and meta-analysis.
Xiang J, Yan H, Li J, Wang X, Chen H, Zheng X
World J Surg Oncol 2019 Feb 13;17(1):31. doi: 10.1186/s12957-019-1573-0. PMID: 30760274Free PMC Article
Adenocarcinoma risk in gastric atrophy and intestinal metaplasia: a systematic review.
Spence AD, Cardwell CR, McMenamin ÚC, Hicks BM, Johnston BT, Murray LJ, Coleman HG
BMC Gastroenterol 2017 Dec 11;17(1):157. doi: 10.1186/s12876-017-0708-4. PMID: 29228909Free PMC Article
A Systematic Review of the Clinical Presentation, Diagnosis, and Treatment of Small Bowel Obstruction.
Rami Reddy SR, Cappell MS
Curr Gastroenterol Rep 2017 Jun;19(6):28. doi: 10.1007/s11894-017-0566-9. PMID: 28439845
Lifestyle Risk Factors for Serrated Colorectal Polyps: A Systematic Review and Meta-analysis.
Bailie L, Loughrey MB, Coleman HG
Gastroenterology 2017 Jan;152(1):92-104. Epub 2016 Sep 14 doi: 10.1053/j.gastro.2016.09.003. PMID: 27639804

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...