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    RPL33B ribosomal 60S subunit protein L33B [ Saccharomyces cerevisiae S288C ]

    Gene ID: 854409, updated on 4-Jan-2025

    Summary

    Official Symbol
    RPL33B
    Official Full Name
    ribosomal 60S subunit protein L33B
    Primary source
    SGD:S000005760
    Locus tag
    YOR234C
    See related
    AllianceGenome:SGD:S000005760; FungiDB:YOR234C; VEuPathDB:YOR234C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    RPL37B
    Summary
    A structural constituent of ribosome. Involved in cytoplasmic translation. Part of cytosolic large ribosomal subunit. Human ortholog(s) of this gene implicated in Diamond-Blackfan anemia 5. Orthologous to human RPL35A (ribosomal protein L35a). [provided by Alliance of Genome Resources, Jan 2025]
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    Genomic context

    See RPL33B in Genome Data Viewer
    Location:
    chromosome: XV
    Exon count:
    2
    Sequence:
    Chromosome: XV; NC_001147.6 (778555..779405, complement)

    Chromosome XV - NC_001147.6Genomic Context describing neighboring genes Neighboring gene Mge1p Neighboring gene putative serine/threonine protein kinase KIN4 Neighboring gene Irc13p Neighboring gene ncRNA Neighboring gene dihydrofolate reductase

    Interactions

    General gene information

    Gene Ontology Provided by SGD

    Process Evidence Code Pubs
    involved_in cytoplasmic translation  
    involved_in cytoplasmic translation PubMed 
    involved_in ribosomal large subunit biogenesis  
    involved_in translation  
    Component Evidence Code Pubs
    located_in cytoplasm  
    part_of cytosolic large ribosomal subunit  
    part_of cytosolic large ribosomal subunit PubMed 
    part_of ribonucleoprotein complex  
    located_in ribosome  

    General protein information

    Preferred Names
    ribosomal 60S subunit protein L33B
    NP_014877.3
    • Ribosomal 60S subunit protein L33B; rpl33b null mutant exhibits normal growth while rpl33a rpl33b double null mutant is inviable; homologous to mammalian ribosomal protein L35A, no bacterial homolog; RPL33B has a paralog, RPL33A, that arose from the whole genome duplication

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001147.6 Reference assembly

      Range
      778555..779405 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001183653.3 → NP_014877.3  TPA: ribosomal 60S subunit protein L33B [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_014877.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W2T8, P41056
      UniProtKB/TrEMBL
      A6ZP75, C8ZGY8, G2WNA4, N1NVW4
      Conserved Domains (1) summary
      pfam01247
      Location:7 → 100
      Ribosomal_L35Ae; Ribosomal protein L35Ae
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