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    SUM1 Sum1p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 851905, updated on 9-Dec-2024

    Summary

    Official Symbol
    SUM1
    Official Full Name
    Sum1p
    Primary source
    SGD:S000002718
    Locus tag
    YDR310C
    See related
    AllianceGenome:SGD:S000002718; FungiDB:YDR310C; VEuPathDB:YDR310C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Enables DNA replication origin binding activity; DNA-binding transcription repressor activity, RNA polymerase II-specific; and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in mitotic cell cycle; negative regulation of macromolecule biosynthetic process; and positive regulation of DNA-templated DNA replication initiation. Located in nucleus. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See SUM1 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    1
    Sequence:
    Chromosome: IV; NC_001136.10 (1081128..1084316, complement)

    Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene Srb7p Neighboring gene Gic2p Neighboring gene TFIIH/NER complex subunit TFB1 Neighboring gene rRNA-binding ribosome biosynthesis protein

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Interactions

    General gene information

    Gene Ontology Provided by SGD

    Component Evidence Code Pubs
    located_in nucleus PubMed 
    located_in nucleus  

    General protein information

    Preferred Names
    Sum1p
    NP_010596.1
    • Transcriptional repressor that regulates middle-sporulation genes; required for mitotic repression of middle sporulation-specific genes; also acts as general replication initiation factor; involved in telomere maintenance, chromatin silencing; regulated by pachytene checkpoint

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001136.10 Reference assembly

      Range
      1081128..1084316 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001180618.1 → NP_010596.1  TPA: Sum1p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_010596.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VST9, P46676
      UniProtKB/TrEMBL
      B3LFY6, C8Z5M1, N1P8L7
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