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    MKT1 Mkt1p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 855639, updated on 9-Dec-2024

    Summary

    Official Symbol
    MKT1
    Official Full Name
    Mkt1p
    Primary source
    SGD:S000005029
    Locus tag
    YNL085W
    See related
    AllianceGenome:SGD:S000005029; FungiDB:YNL085W; VEuPathDB:YNL085W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Predicted to enable DNA endonuclease activity and mRNA 3'-UTR binding activity. Involved in DNA damage response. Located in P-body and nuclear periphery. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See MKT1 in Genome Data Viewer
    Location:
    chromosome: XIV
    Exon count:
    1
    Sequence:
    Chromosome: XIV; NC_001146.8 (467131..469623)

    Chromosome XIV - NC_001146.8Genomic Context describing neighboring genes Neighboring gene tricalbin Neighboring gene Snn1p Neighboring gene End3p Neighboring gene Ca(2+)-binding ATP:ADP antiporter SAL1

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Interactions

    General gene information

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables DNA endonuclease activity PubMed 
    enables mRNA 3'-UTR binding  
    enables nuclease activity  
    Process Evidence Code Pubs
    involved_in DNA damage response  
    involved_in DNA damage response PubMed 
    involved_in DNA metabolic process  
    involved_in regulation of translation  
    Component Evidence Code Pubs
    located_in P-body PubMed 
    located_in cytoplasm PubMed 
    located_in cytoplasm  
    located_in cytoplasmic stress granule PubMed 
    located_in cytosol  
    located_in nuclear periphery PubMed 

    General protein information

    Preferred Names
    Mkt1p
    NP_014314.3
    • Protein similar to nucleases that forms a complex with Pbp1p; complex may mediate posttranscriptional regulation of HO; involved in propagation of M2 dsRNA satellite of L-A virus; allelic variation affects mitochondrial genome stability, drug resistance, and more; forms cytoplasmic foci upon DNA replication stress; localization to P-bodies under ethanol stress differs between strains

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001146.8 Reference assembly

      Range
      467131..469623
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001182923.3 → NP_014314.3  TPA: Mkt1p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_014314.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W194, P40850, Q45T81, Q8TF89
      UniProtKB/TrEMBL
      A6ZRZ5, B3LNU4, C8ZGE5, N1NXY4
      Conserved Domains (1) summary
      COG5366
      Location:10 → 746
      COG5366; Protein involved in propagation of M2 dsRNA satellite of L-A virus [General function prediction only]
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