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Benign Hair Follicle Neoplasm

MedGen UID:: 163114
•Concept ID:: C0853031
•: Neoplastic Process

Synonyms:

Benign Follicular Neoplasm; Benign Follicular Tumor; Benign Hair Follicle Tumor

Definition

A neoplasm that arises from the hair follicle and is characterized by the absence of atypical or malignant cytological and architectural features, and absence of invasive features or metastatic potential. [from NCI]

Term Hierarchy

Professional guidelines

PubMed

Intralesional therapy for the treatment of keratoacanthoma.

Kiss N, Avci P, Bánvölgyi A, Lőrincz K, Szakonyi J, Gyöngyösi N, Fésűs L, Lee G, Wikonkál N
Dermatol Ther 2019 May;32(3):e12872. Epub 2019 Apr 4 doi: 10.1111/dth.12872. PMID: 30866135

Malignant hair follicle tumors of the periorbital region: A review of literature and suggestion of a management guideline.

Sia PI, Figueira E, Allende A, Selva D
Orbit 2016 Jun;35(3):144-56. Epub 2016 May 12 doi: 10.1080/01676830.2016.1176048. PMID: 27171562

Epidemiology, diagnosis and management of hirsutism: a consensus statement by the Androgen Excess and Polycystic Ovary Syndrome Society.

Escobar-Morreale HF, Carmina E, Dewailly D, Gambineri A, Kelestimur F, Moghetti P, Pugeat M, Qiao J, Wijeyaratne CN, Witchel SF, Norman RJ
Hum Reprod Update 2012 Mar-Apr;18(2):146-70. Epub 2011 Nov 6 doi: 10.1093/humupd/dmr042. PMID: 22064667

See all (8)

Recent clinical studies

Etiology

Genetics of adnexal tumors: An update.

Kervarrec T, Sohier P, Pissaloux D, de la Fouchardiere A, Cribier B, Battistella M, Macagno N
Ann Dermatol Venereol 2023 Sep;150(3):202-207. Epub 2023 Jun 1 doi: 10.1016/j.annder.2023.03.003. PMID: 37270318

Follicular induction and CK20+ Merkel cells overlying cutaneous focal mucinosis.

Chairatchaneeboon M, Elenitsas R, Nguyen JV
J Cutan Pathol 2019 Mar;46(3):195-198. Epub 2019 Jan 14 doi: 10.1111/cup.13402. PMID: 30552701

Benign follicular tumors.

Tellechea O, Cardoso JC, Reis JP, Ramos L, Gameiro AR, Coutinho I, Baptista AP
An Bras Dermatol 2015 Nov-Dec;90(6):780-96; quiz 797-8. doi: 10.1590/abd1806-4841.20154114. PMID: 26734858 Free PMC Article

Is Tumor of Follicular Infundibulum a Reaction to Dermal Scarring?

Baquerizo Nole KL, Lopez-Garcia DR, Teague DJ, Al Sayyah A, Mansoori P, Salim Al Alshehri H, Sangüeza OP
Am J Dermatopathol 2015 Jul;37(7):535-8. doi: 10.1097/DAD.0000000000000130. PMID: 25051108

Birt-Hogg-Dubé syndrome.

Lencastre A, Ponte P, Apetato M, Nunes L, Lestre S
An Bras Dermatol 2013 Nov-Dec;88(6 Suppl 1):203-5. doi: 10.1590/abd1806-4841.20132199. PMID: 24346920 Free PMC Article

See all (58)

Diagnosis

Genetics of adnexal tumors: An update.

Pilomatrixoma: A Comprehensive Review of the Literature.

Jones CD, Ho W, Robertson BF, Gunn E, Morley S
Am J Dermatopathol 2018 Sep;40(9):631-641. doi: 10.1097/DAD.0000000000001118. PMID: 30119102

Folliculosebaceous neoplasms: A review of clinical and histological features.

Ho J, Bhawan J
J Dermatol 2017 Mar;44(3):259-278. doi: 10.1111/1346-8138.13773. PMID: 28256760

Giant melanotrichoblastoma.

Kim DW, Lee JH, Kim I
Am J Dermatopathol 2011 May;33(3):e37-40. doi: 10.1097/DAD.0b013e3181dfd120. PMID: 20940620

Basaloid follicular hamartoma.

Mills O, Thomas LB
Arch Pathol Lab Med 2010 Aug;134(8):1215-9. doi: 10.5858/2008-0620-RS.1. PMID: 20670146

See all (183)

Therapy

Development of Pilomatrixoma at the Vaccination Site: A Rare Complication of COVID-19 Vaccination - A Case Report.

Yang Z, Song F, Winters L, Zhong J
Am J Case Rep 2023 Dec 6;24:e942280. doi: 10.12659/AJCR.942280. PMID: 38055654 Free PMC Article

Intralesional therapy for the treatment of keratoacanthoma.

Kiss N, Avci P, Bánvölgyi A, Lőrincz K, Szakonyi J, Gyöngyösi N, Fésűs L, Lee G, Wikonkál N
Dermatol Ther 2019 May;32(3):e12872. Epub 2019 Apr 4 doi: 10.1111/dth.12872. PMID: 30866135

Punch and Scoop Technique for Removing Pilomatricoma.

Maranda EL, Riyaz F, Shwayder T
Pediatr Dermatol 2017 Sep;34(5):622-623. Epub 2017 Aug 7 doi: 10.1111/pde.13215. PMID: 28783214

Molecular pathology of skin neoplasms of the head and neck.

Kraft S, Granter SR
Arch Pathol Lab Med 2014 Jun;138(6):759-87. doi: 10.5858/arpa.2013-0157-RA. PMID: 24878016

Differentiation between basal cell carcinoma and trichoepithelioma by immunohistochemical staining of the androgen receptor: an overview.

Arits AH, Van Marion AM, Lohman BG, Thissen MR, Steijlen PM, Nelemans PJ, Kelleners-Smeets NW
Eur J Dermatol 2011 Nov-Dec;21(6):870-3. doi: 10.1684/ejd.2011.1504. PMID: 21865121

See all (8)

Prognosis

Syringotropic Mycosis Fungoides: A Variant of Folliculotropic or a Distinct Subtype of Adnexotropic Mycosis Fungoides?

Nussbaum D, Eleryan M, Samaan C, Glass F, Prussick R
J Drugs Dermatol 2022 Dec 1;21(12):1362-1364. doi: 10.36849/JDD.6779. PMID: 36468959

Trichoepithelioma Misdiagnosed as Basal Cell Carcinoma.

Kang KJ, Seo BF, Shin J, Kwon H, Byeon JH, Jung SN
J Craniofac Surg 2019 May/Jun;30(3):e197-e199. doi: 10.1097/SCS.0000000000005089. PMID: 30394977

Pilomatrixoma: A Comprehensive Review of the Literature.

Jones CD, Ho W, Robertson BF, Gunn E, Morley S
Am J Dermatopathol 2018 Sep;40(9):631-641. doi: 10.1097/DAD.0000000000001118. PMID: 30119102

Multiple pilomatrixoma in Turner syndrome.

Bengtzen AR, Grossniklaus HE, Bernardino CR
Ophthalmic Plast Reconstr Surg 2009 May-Jun;25(3):229-30. doi: 10.1097/IOP.0b013e3181a146c7. PMID: 19454938

Malignant adnexal neoplasms.

Crowson AN, Magro CM, Mihm MC
Mod Pathol 2006 Feb;19 Suppl 2:S93-S126. doi: 10.1038/modpathol.3800511. PMID: 16446719

See all (36)

Clinical prediction guides

Trichoepithelioma Misdiagnosed as Basal Cell Carcinoma.

Kang KJ, Seo BF, Shin J, Kwon H, Byeon JH, Jung SN
J Craniofac Surg 2019 May/Jun;30(3):e197-e199. doi: 10.1097/SCS.0000000000005089. PMID: 30394977

Pilomatrixoma: A Comprehensive Review of the Literature.

Jones CD, Ho W, Robertson BF, Gunn E, Morley S
Am J Dermatopathol 2018 Sep;40(9):631-641. doi: 10.1097/DAD.0000000000001118. PMID: 30119102

Birt-Hogg-Dubé syndrome.

Lencastre A, Ponte P, Apetato M, Nunes L, Lestre S
An Bras Dermatol 2013 Nov-Dec;88(6 Suppl 1):203-5. doi: 10.1590/abd1806-4841.20132199. PMID: 24346920 Free PMC Article

Ossifying trichilemmal cyst.

Pusiol T, Morichetti D, Zorzi MG, Piscioli F
Am J Dermatopathol 2011 Dec;33(8):867-8. doi: 10.1097/DAD.0b013e31821b0abd. PMID: 22042263

Familial multiple cutaneous leiomyomas.

Fernández-Pugnaire MA, Delgado-Florencio V
Dermatology 1995;191(4):295-8. doi: 10.1159/000246578. PMID: 8573925

See all (61)

Recent systematic reviews

A systematic review of Pilomatrix carcinoma arising from the previous scar site of Pilomatrixoma.

Panda SK, Sahoo PK, Agarwala SK, Houghton TT, Sankar KV, Mohanty P
J Cancer Res Ther 2023 Jul-Sep;19(5):1098-1102. doi: 10.4103/jcrt.jcrt_720_21. PMID: 37787269

Dermoscopy of cutaneous adnexal tumours: a systematic review of the literature.

Lai M, Muscianese M, Piana S, Chester J, Borsari S, Paolino G, Pellacani G, Longo C, Pampena R
J Eur Acad Dermatol Venereol 2022 Sep;36(9):1524-1540. Epub 2022 May 25 doi: 10.1111/jdv.18210. PMID: 35536546 Free PMC Article

Epidemiology, diagnosis and management of hirsutism: a consensus statement by the Androgen Excess and Polycystic Ovary Syndrome Society.

See all (3)

MedGen

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Benign Hair Follicle Neoplasm

Definition

Term Hierarchy

Professional guidelines

PubMed

Recent clinical studies

Etiology

Diagnosis

Therapy

Prognosis

Clinical prediction guides

Recent systematic reviews

Supplemental Content

Table of contents

Practice guidelines

Related information

Recent activity