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Cystadenocarcinoma

MedGen UID:
41385
Concept ID:
C0010631
Neoplastic Process
Synonym: Cystadenocarcinomas
SNOMED CT: Cystadenocarcinoma (21008007)
 
Monarch Initiative: MONDO:0005596

Definition

A malignant cystic epithelial neoplasm arising from the glandular epithelium. The malignant epithelial cells invade the stroma. The cystic spaces contain serous or mucinous fluid. Representative examples include ovarian and pancreatic cystadenocarcinomas. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVCystadenocarcinoma

Professional guidelines

PubMed

Zhao S, Li Y, Xu J, Shen L
Neurol Res 2024 Mar;46(3):227-242. Epub 2024 Jan 22 doi: 10.1080/01616412.2023.2287340. PMID: 38007705
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Am J Surg Pathol 2022 Sep 1;46(9):1219-1233. Epub 2022 Jul 4 doi: 10.1097/PAS.0000000000001930. PMID: 35778790
Lee YT
Curr Surg 1989 May-Jun;46(3):202-6. PMID: 2666031

Recent clinical studies

Etiology

Ahn B, Moon D, Kim HS, Lee C, Cho NH, Choi HK, Kim D, Lee JY, Nam EJ, Won D, An HJ, Kwon SY, Shin SJ, Jung HR, Kwon D, Park H, Kim M, Cha YJ, Park H, Lee Y, Noh S, Lee YM, Choi SE, Kim JM, Sung SH, Park E
Nat Commun 2024 May 18;15(1):4253. doi: 10.1038/s41467-024-48667-6. PMID: 38762636Free PMC Article
Slomovitz B, Gourley C, Carey MS, Malpica A, Shih IM, Huntsman D, Fader AN, Grisham RN, Schlumbrecht M, Sun CC, Ludemann J, Cooney GA, Coleman R, Sood AK, Mahdi H, Wong KK, Covens A, O'Malley DM, Lecuru F, Cobb LP, Caputo TA, May T, Huang M, Siemon J, Fernández ML, Ray-Coquard I, Gershenson DM
Gynecol Oncol 2020 Mar;156(3):715-725. Epub 2020 Jan 20 doi: 10.1016/j.ygyno.2019.12.033. PMID: 31969252
Lisio MA, Fu L, Goyeneche A, Gao ZH, Telleria C
Int J Mol Sci 2019 Feb 22;20(4) doi: 10.3390/ijms20040952. PMID: 30813239Free PMC Article
Kim TS, Fernandez-del Castillo C
Hematol Oncol Clin North Am 2015 Aug;29(4):655-74. Epub 2015 Jun 6 doi: 10.1016/j.hoc.2015.04.002. PMID: 26226903
Devouassoux-Shisheboran M, Genestie C
Chin J Cancer 2015 Jan;34(1):50-5. doi: 10.5732/cjc.014.10273. PMID: 25556618Free PMC Article

Diagnosis

Toffolo Pasquini M, Aragone L, Scasso Rebdza V, Nardi W, Toscano M, Quildrian S
Medicina (B Aires) 2024;84(4):750-755. PMID: 39172576
Kotsopoulos IC, Papanikolaou A, Lambropoulos AF, Papazisis KT, Tsolakidis D, Touplikioti P, Tarlatzis BC
Int J Gynecol Cancer 2014 Mar;24(3):410-7. doi: 10.1097/IGC.0000000000000079. PMID: 24476895
del Carmen MG, Birrer M, Schorge JO
Gynecol Oncol 2012 Dec;127(3):651-61. Epub 2012 Sep 20 doi: 10.1016/j.ygyno.2012.09.012. PMID: 23000148
Roggin KK, Chennat J, Oto A, Noffsinger A, Briggs A, Matthews JB
Curr Probl Surg 2010 Jun;47(6):459-510. doi: 10.1067/j.cpsurg.2010.02.002. PMID: 20451023
Afifi K, Thomas DH, Bhaumik J
J Obstet Gynaecol 2009 Jul;29(5):453-4. doi: 10.1080/01443610902968543. PMID: 19603339

Therapy

Grisham RN, Slomovitz BM, Andrews N, Banerjee S, Brown J, Carey MS, Chui H, Coleman RL, Fader AN, Gaillard S, Gourley C, Sood AK, Monk BJ, Moore KN, Ray-Coquard I, Shih IM, Westin SN, Wong KK, Gershenson DM
Int J Gynecol Cancer 2023 Sep 4;33(9):1331-1344. doi: 10.1136/ijgc-2023-004610. PMID: 37591609Free PMC Article
Bogani G, Ray-Coquard I, Concin N, Ngoi NYL, Morice P, Enomoto T, Takehara K, Denys H, Nout RA, Lorusso D, Vaughan MM, Bini M, Takano M, Provencher D, Indini A, Sagae S, Wimberger P, Póka R, Segev Y, Kim SI, Candido Dos Reis FJ, Lopez S, Mariani A, Leitao MM Jr, Raspagliesi F, Panici PB, Di Donato V, Muzii L, Colombo N, Scambia G, Pignata S, Monk BJ
Gynecol Oncol 2021 Jul;162(1):226-234. Epub 2021 Apr 30 doi: 10.1016/j.ygyno.2021.04.029. PMID: 33934848Free PMC Article
Slomovitz B, Gourley C, Carey MS, Malpica A, Shih IM, Huntsman D, Fader AN, Grisham RN, Schlumbrecht M, Sun CC, Ludemann J, Cooney GA, Coleman R, Sood AK, Mahdi H, Wong KK, Covens A, O'Malley DM, Lecuru F, Cobb LP, Caputo TA, May T, Huang M, Siemon J, Fernández ML, Ray-Coquard I, Gershenson DM
Gynecol Oncol 2020 Mar;156(3):715-725. Epub 2020 Jan 20 doi: 10.1016/j.ygyno.2019.12.033. PMID: 31969252
Friedlander M, Matulonis U, Gourley C, du Bois A, Vergote I, Rustin G, Scott C, Meier W, Shapira-Frommer R, Safra T, Matei D, Shirinkin V, Selle F, Fielding A, Lowe ES, McMurtry EL, Spencer S, Rowe P, Mann H, Parry D, Ledermann J
Br J Cancer 2018 Oct;119(9):1075-1085. Epub 2018 Oct 24 doi: 10.1038/s41416-018-0271-y. PMID: 30353045Free PMC Article
Fader AN, Roque DM, Siegel E, Buza N, Hui P, Abdelghany O, Chambers SK, Secord AA, Havrilesky L, O'Malley DM, Backes F, Nevadunsky N, Edraki B, Pikaart D, Lowery W, ElSahwi KS, Celano P, Bellone S, Azodi M, Litkouhi B, Ratner E, Silasi DA, Schwartz PE, Santin AD
J Clin Oncol 2018 Jul 10;36(20):2044-2051. Epub 2018 Mar 27 doi: 10.1200/JCO.2017.76.5966. PMID: 29584549

Prognosis

Jiménez A, Chiva L
Int J Gynecol Cancer 2024 Sep 2;34(9):1479-1480. doi: 10.1136/ijgc-2024-005340. PMID: 38531537
Banerjee S, Moore KN, Colombo N, Scambia G, Kim BG, Oaknin A, Friedlander M, Lisyanskaya A, Floquet A, Leary A, Sonke GS, Gourley C, Oza A, González-Martín A, Aghajanian C, Bradley WH, Holmes E, Lowe ES, DiSilvestro P
Lancet Oncol 2021 Dec;22(12):1721-1731. Epub 2021 Oct 26 doi: 10.1016/S1470-2045(21)00531-3. PMID: 34715071
Peres LC, Cushing-Haugen KL, Köbel M, Harris HR, Berchuck A, Rossing MA, Schildkraut JM, Doherty JA
J Natl Cancer Inst 2019 Jan 1;111(1):60-68. doi: 10.1093/jnci/djy071. PMID: 29718305Free PMC Article
Bowtell DD, Böhm S, Ahmed AA, Aspuria PJ, Bast RC Jr, Beral V, Berek JS, Birrer MJ, Blagden S, Bookman MA, Brenton JD, Chiappinelli KB, Martins FC, Coukos G, Drapkin R, Edmondson R, Fotopoulou C, Gabra H, Galon J, Gourley C, Heong V, Huntsman DG, Iwanicki M, Karlan BY, Kaye A, Lengyel E, Levine DA, Lu KH, McNeish IA, Menon U, Narod SA, Nelson BH, Nephew KP, Pharoah P, Powell DJ Jr, Ramos P, Romero IL, Scott CL, Sood AK, Stronach EA, Balkwill FR
Nat Rev Cancer 2015 Nov;15(11):668-79. doi: 10.1038/nrc4019. PMID: 26493647Free PMC Article
Roelofsen T, van Ham MA, de Hullu JA, Massuger LF
Expert Rev Anticancer Ther 2011 Jan;11(1):71-81. doi: 10.1586/era.10.199. PMID: 21166512

Clinical prediction guides

Kim SR, Parbhakar A, Li X, Bernardini MQ, Hogen L, May T
Int J Gynecol Cancer 2024 Jun 3;34(6):879-885. doi: 10.1136/ijgc-2023-005065. PMID: 38548312
Nesic K, Kondrashova O, Hurley RM, McGehee CD, Vandenberg CJ, Ho GY, Lieschke E, Dall G, Bound N, Shield-Artin K, Radke M, Musafer A, Chai ZQ, Ghamsari MRE, Harrell MI, Kee D, Olesen I, McNally O, Traficante N, Australian Ovarian Cancer Study, DeFazio A, Bowtell DDL, Swisher EM, Weroha SJ, Nones K, Waddell N, Kaufmann SH, Dobrovic A, Wakefield MJ, Scott CL
Cancer Res 2021 Sep 15;81(18):4709-4722. Epub 2021 Jul 28 doi: 10.1158/0008-5472.CAN-21-0774. PMID: 34321239
Singh N, Piskorz AM, Bosse T, Jimenez-Linan M, Rous B, Brenton JD, Gilks CB, Köbel M
J Pathol 2020 Mar;250(3):336-345. Epub 2020 Jan 29 doi: 10.1002/path.5375. PMID: 31829441
Matulonis UA, Shapira-Frommer R, Santin AD, Lisyanskaya AS, Pignata S, Vergote I, Raspagliesi F, Sonke GS, Birrer M, Provencher DM, Sehouli J, Colombo N, González-Martín A, Oaknin A, Ottevanger PB, Rudaitis V, Katchar K, Wu H, Keefe S, Ruman J, Ledermann JA
Ann Oncol 2019 Jul 1;30(7):1080-1087. doi: 10.1093/annonc/mdz135. PMID: 31046082
Antonini F, Fuccio L, Fabbri C, Macarri G, Palazzo L
Expert Rev Gastroenterol Hepatol 2015 Jan;9(1):115-25. Epub 2014 Jul 1 doi: 10.1586/17474124.2014.934675. PMID: 24981593

Recent systematic reviews

Scaglione G, Travaglino A, Raffone A, Santoro A, Arciuolo D, Fulgione C, D'Alessandris N, Pannone G, Urtueta BP, Narducci N, Addante F, Casarin J, Ronchi S, Di Lauro E, La Rosa S, Maccio L, Inzani F, Zannoni GF
Pathol Res Pract 2024 Dec;264:155714. Epub 2024 Nov 6 doi: 10.1016/j.prp.2024.155714. PMID: 39520971
Matsuo K, Matsuzaki S, Maeda M, Rau AR, Yoshihara K, Tamura R, Shimada M, Machida H, Mikami M, Klar M, Roman LD, Wright JD, Sood AK, Gershenson DM
JAMA Netw Open 2023 Jun 1;6(6):e2318602. doi: 10.1001/jamanetworkopen.2023.18602. PMID: 37326992Free PMC Article
Ruel-Laliberté J, Kasasni SM, Oprea D, Viau M
J Obstet Gynaecol Can 2022 Nov;44(11):1174-1180. Epub 2022 Sep 12 doi: 10.1016/j.jogc.2022.08.018. PMID: 36099965
Pellegrino B, Sikokis A, Bersanelli M, Leonetti A, Leonardi F, Di Meglio G, Buti S
Gynecol Obstet Invest 2016;81(5):385-93. Epub 2016 Jun 17 doi: 10.1159/000446954. PMID: 27309542
Steinhagen PR, Sehouli J
Anticancer Res 2011 Apr;31(4):1387-94. PMID: 21508390

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