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Thoracic cancer

MedGen UID:
56320
•Concept ID:
C0153661
•
Neoplastic Process
Synonyms: cancer of thoracic segment of trunk; Malignant Neoplasm of the Thorax; malignant neoplasm of the thorax; malignant neoplasm of thoracic segment of trunk; Malignant neoplasm of thorax; Malignant Neoplasm of Thorax; malignant neoplasm of thorax; Malignant Thoracic Neoplasm; malignant thoracic neoplasm; malignant thoracic segment of trunk neoplasm; Malignant Thoracic Tumor; malignant thoracic tumor; malignant thoracic tumour; Malignant Tumor of the Thorax; malignant tumor of the thorax; Malignant tumor of thorax; Malignant Tumor of Thorax; malignant tumor of thorax; malignant tumour of the thorax; malignant tumour of thorax; thoracic cancer; thoracic segment of trunk cancer; thorax cancer
SNOMED CT: Malignant neoplasm of thorax (188361007); Malignant tumor of thorax (188361007)
 
Monarch Initiative: MONDO:0003274

Definition

A primary or metastatic malignant neoplasm affecting the tissues of the thorax. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVThoracic cancer

Professional guidelines

PubMed

Systemic Therapy for Small-Cell Lung Cancer: ASCO-Ontario Health (Cancer Care Ontario) Guideline.
Khurshid H, Ismaila N, Bian J, Dabney R, Das M, Ellis P, Feldman J, Hann C, Kulkarni S, Laskin J, Manochakian R, Mishra DR, Preeshagul I, Reddy P, Saxena A, Weinberg F, Kalemkerian GP
J Clin Oncol 2023 Dec 10;41(35):5448-5472. Epub 2023 Oct 11 doi: 10.1200/JCO.23.01435. PMID: 37820295
Clinical decision support for chemotherapy-induced neutropenia using a hybrid pharmacodynamic/machine learning model.
Hughes JH, Tong DMH, Burns V, Daly B, Razavi P, Boelens JJ, Goswami S, Keizer RJ
CPT Pharmacometrics Syst Pharmacol 2023 Nov;12(11):1764-1776. Epub 2023 Aug 10 doi: 10.1002/psp4.13019. PMID: 37503916Free PMC Article
Management of Stage III Non-Small-Cell Lung Cancer: ASCO Guideline.
Daly ME, Singh N, Ismaila N, Antonoff MB, Arenberg DA, Bradley J, David E, Detterbeck F, Früh M, Gubens MA, Moore AC, Padda SK, Patel JD, Phillips T, Qin A, Robinson C, Simone CB 2nd
J Clin Oncol 2022 Apr 20;40(12):1356-1384. Epub 2021 Dec 22 doi: 10.1200/JCO.21.02528. PMID: 34936470

Recent clinical studies

Etiology

Identification of a novel anoikis-related gene signature to predict prognosis and tumor microenvironment in lung adenocarcinoma.
Diao X, Guo C, Li S
Thorac Cancer 2023 Jan;14(3):320-330. Epub 2022 Dec 11 doi: 10.1111/1759-7714.14766. PMID: 36507553Free PMC Article
Epidemiology of esophageal cancer in 2020 and projections to 2030 and 2040.
Liu CQ, Ma YL, Qin Q, Wang PH, Luo Y, Xu PF, Cui Y
Thorac Cancer 2023 Jan;14(1):3-11. Epub 2022 Dec 8 doi: 10.1111/1759-7714.14745. PMID: 36482832Free PMC Article
UNcommon EGFR Mutations: International Case Series on Efficacy of Osimertinib in Real-Life Practice in First-LiNe Setting (UNICORN).
Bar J, Peled N, Schokrpur S, Wolner M, Rotem O, Girard N, Aboubakar Nana F, Derijcke S, Kian W, Patel S, Gantz-Sorotsky H, Zer A, Moskovitz M, Metro G, Rottenberg Y, Calles A, Hochmair M, Cuppens K, Decoster L, Reck M, Limon D, Rodriguez E, Astaras C, Bettini A, Häfliger S, Addeo A
J Thorac Oncol 2023 Feb;18(2):169-180. Epub 2022 Oct 25 doi: 10.1016/j.jtho.2022.10.004. PMID: 36307041
Comparison of ultrasound and mammography for early diagnosis of breast cancer among Chinese women with suspected breast lesions: A prospective trial.
Wang Y, Li Y, Song Y, Chen C, Wang Z, Li L, Liu M, Liu G, Xu Y, Zhou Y, Sun Q, Shen S
Thorac Cancer 2022 Nov;13(22):3145-3151. Epub 2022 Sep 30 doi: 10.1111/1759-7714.14666. PMID: 36177910Free PMC Article
Epidemiology of lung cancer in China.
Cao M, Chen W
Thorac Cancer 2019 Jan;10(1):3-7. Epub 2018 Nov 28 doi: 10.1111/1759-7714.12916. PMID: 30485694Free PMC Article

Diagnosis

The role of microbiota in esophageal squamous cell carcinoma: A review of the literature.
Chiang HC, Hughes M, Chang WL
Thorac Cancer 2023 Oct;14(28):2821-2829. Epub 2023 Sep 7 doi: 10.1111/1759-7714.15096. PMID: 37675608Free PMC Article
Lung Cancer, Covid-19 Infections and Chemotherapy.
Haineala B, Zgura A, Badiu DC, Iliescu L, Anghel RM, Bacinschi XE
In Vivo 2021 May-Jun;35(3):1877-1880. doi: 10.21873/invivo.12450. PMID: 33910875Free PMC Article
Expression and role of p16 and GLUT1 in malignant diseases and lung cancer: A review.
Pezzuto A, D'Ascanio M, Ricci A, Pagliuca A, Carico E
Thorac Cancer 2020 Nov;11(11):3060-3070. Epub 2020 Sep 18 doi: 10.1111/1759-7714.13651. PMID: 32945604Free PMC Article
Comparison and discussion of the treatment guidelines for small cell lung cancer.
Zhao H, Ren D, Liu H, Chen J
Thorac Cancer 2018 Jul;9(7):769-774. Epub 2018 May 16 doi: 10.1111/1759-7714.12765. PMID: 29770597Free PMC Article
Lung cancer: needs assessment, treatment and therapies.
Evans M
Br J Nurs 2013 Sep 12-25;22(17):S15-6, S18, S20-2. doi: 10.12968/bjon.2013.22.Sup17.S15. PMID: 24067269

Therapy

Malignant Superior Vena Cava Syndrome: A Scoping Review.
Wright K, Digby GC, Gyawali B, Jad R, Menard A, Moraes FY, Wijeratne DT
J Thorac Oncol 2023 Oct;18(10):1268-1276. Epub 2023 May 3 doi: 10.1016/j.jtho.2023.04.019. PMID: 37146753
Management of Stage III Non-Small-Cell Lung Cancer: ASCO Guideline.
Daly ME, Singh N, Ismaila N, Antonoff MB, Arenberg DA, Bradley J, David E, Detterbeck F, Früh M, Gubens MA, Moore AC, Padda SK, Patel JD, Phillips T, Qin A, Robinson C, Simone CB 2nd
J Clin Oncol 2022 Apr 20;40(12):1356-1384. Epub 2021 Dec 22 doi: 10.1200/JCO.21.02528. PMID: 34936470
The cutting-edge progress of immune-checkpoint blockade in lung cancer.
Zhou F, Qiao M, Zhou C
Cell Mol Immunol 2021 Feb;18(2):279-293. Epub 2020 Nov 11 doi: 10.1038/s41423-020-00577-5. PMID: 33177696Free PMC Article
Epidemiology of lung cancer in China.
Cao M, Chen W
Thorac Cancer 2019 Jan;10(1):3-7. Epub 2018 Nov 28 doi: 10.1111/1759-7714.12916. PMID: 30485694Free PMC Article
STK11/LKB1 Mutations and PD-1 Inhibitor Resistance in KRAS-Mutant Lung Adenocarcinoma.
Skoulidis F, Goldberg ME, Greenawalt DM, Hellmann MD, Awad MM, Gainor JF, Schrock AB, Hartmaier RJ, Trabucco SE, Gay L, Ali SM, Elvin JA, Singal G, Ross JS, Fabrizio D, Szabo PM, Chang H, Sasson A, Srinivasan S, Kirov S, Szustakowski J, Vitazka P, Edwards R, Bufill JA, Sharma N, Ou SI, Peled N, Spigel DR, Rizvi H, Aguilar EJ, Carter BW, Erasmus J, Halpenny DF, Plodkowski AJ, Long NM, Nishino M, Denning WL, Galan-Cobo A, Hamdi H, Hirz T, Tong P, Wang J, Rodriguez-Canales J, Villalobos PA, Parra ER, Kalhor N, Sholl LM, Sauter JL, Jungbluth AA, Mino-Kenudson M, Azimi R, Elamin YY, Zhang J, Leonardi GC, Jiang F, Wong KK, Lee JJ, Papadimitrakopoulou VA, Wistuba II, Miller VA, Frampton GM, Wolchok JD, Shaw AT, Jänne PA, Stephens PJ, Rudin CM, Geese WJ, Albacker LA, Heymach JV
Cancer Discov 2018 Jul;8(7):822-835. Epub 2018 May 17 doi: 10.1158/2159-8290.CD-18-0099. PMID: 29773717Free PMC Article

Prognosis

The role of microbiota in esophageal squamous cell carcinoma: A review of the literature.
Chiang HC, Hughes M, Chang WL
Thorac Cancer 2023 Oct;14(28):2821-2829. Epub 2023 Sep 7 doi: 10.1111/1759-7714.15096. PMID: 37675608Free PMC Article
Tepotinib Treatment in Patients With MET Exon 14-Skipping Non-Small Cell Lung Cancer: Long-term Follow-up of the VISION Phase 2 Nonrandomized Clinical Trial.
Mazieres J, Paik PK, Garassino MC, Le X, Sakai H, Veillon R, Smit EF, Cortot AB, Raskin J, Viteri S, Wu YL, Yang JCH, Ahn MJ, Ma R, Zhao J, O'Brate A, Berghoff K, Bruns R, Otto G, Johne A, Felip E, Thomas M
JAMA Oncol 2023 Sep 1;9(9):1260-1266. doi: 10.1001/jamaoncol.2023.1962. PMID: 37270698Free PMC Article
Identification of a novel anoikis-related gene signature to predict prognosis and tumor microenvironment in lung adenocarcinoma.
Diao X, Guo C, Li S
Thorac Cancer 2023 Jan;14(3):320-330. Epub 2022 Dec 11 doi: 10.1111/1759-7714.14766. PMID: 36507553Free PMC Article
Epidemiology of esophageal cancer in 2020 and projections to 2030 and 2040.
Liu CQ, Ma YL, Qin Q, Wang PH, Luo Y, Xu PF, Cui Y
Thorac Cancer 2023 Jan;14(1):3-11. Epub 2022 Dec 8 doi: 10.1111/1759-7714.14745. PMID: 36482832Free PMC Article
The cutting-edge progress of immune-checkpoint blockade in lung cancer.
Zhou F, Qiao M, Zhou C
Cell Mol Immunol 2021 Feb;18(2):279-293. Epub 2020 Nov 11 doi: 10.1038/s41423-020-00577-5. PMID: 33177696Free PMC Article

Clinical prediction guides

Cellular dynamics in tumour microenvironment along with lung cancer progression underscore spatial and evolutionary heterogeneity of neutrophil.
Peng H, Wu X, Liu S, He M, Tang C, Wen Y, Xie C, Zhong R, Li C, Xiong S, Liu J, Zheng H, He J, Lu X, Liang W
Clin Transl Med 2023 Jul;13(7):e1340. doi: 10.1002/ctm2.1340. PMID: 37491740Free PMC Article
Identification of a novel anoikis-related gene signature to predict prognosis and tumor microenvironment in lung adenocarcinoma.
Diao X, Guo C, Li S
Thorac Cancer 2023 Jan;14(3):320-330. Epub 2022 Dec 11 doi: 10.1111/1759-7714.14766. PMID: 36507553Free PMC Article
Lung Cancer, Covid-19 Infections and Chemotherapy.
Haineala B, Zgura A, Badiu DC, Iliescu L, Anghel RM, Bacinschi XE
In Vivo 2021 May-Jun;35(3):1877-1880. doi: 10.21873/invivo.12450. PMID: 33910875Free PMC Article
The cutting-edge progress of immune-checkpoint blockade in lung cancer.
Zhou F, Qiao M, Zhou C
Cell Mol Immunol 2021 Feb;18(2):279-293. Epub 2020 Nov 11 doi: 10.1038/s41423-020-00577-5. PMID: 33177696Free PMC Article
Non-canonical functions of the mitotic kinesin Eg5.
Liu M, Ran J, Zhou J
Thorac Cancer 2018 Aug;9(8):904-910. Epub 2018 Jun 21 doi: 10.1111/1759-7714.12792. PMID: 29927078Free PMC Article

Recent systematic reviews

Evaluation of Clinical and Safety Outcomes of Neoadjuvant Immunotherapy Combined With Chemotherapy for Patients With Resectable Esophageal Cancer: A Systematic Review and Meta-analysis.
Ge F, Huo Z, Cai X, Hu Q, Chen W, Lin G, Zhong R, You Z, Wang R, Lu Y, Wang R, Huang Q, Zhang H, Song A, Li C, Wen Y, Jiang Y, Liang H, He J, Liang W, Liu J
JAMA Netw Open 2022 Nov 1;5(11):e2239778. doi: 10.1001/jamanetworkopen.2022.39778. PMID: 36322089Free PMC Article
Lung cancer risk prediction models based on pulmonary nodules: A systematic review.
Wu Z, Wang F, Cao W, Qin C, Dong X, Yang Z, Zheng Y, Luo Z, Zhao L, Yu Y, Xu Y, Li J, Tang W, Shen S, Wu N, Tan F, Li N, He J
Thorac Cancer 2022 Mar;13(5):664-677. Epub 2022 Feb 8 doi: 10.1111/1759-7714.14333. PMID: 35137543Free PMC Article
Sublobar resection is associated with improved outcomes over radiotherapy in the management of high-risk elderly patients with Stage I non-small cell lung cancer: a systematic review and meta-analysis.
Wang HH, Zhang CZ, Zhang BL, Chen J, Zeng XL, Deng L, Meng MB
Oncotarget 2017 Jan 24;8(4):6033-6042. doi: 10.18632/oncotarget.14010. PMID: 28002808Free PMC Article
Neuromuscular electrical stimulation for muscle weakness in adults with advanced disease.
Jones S, Man WD, Gao W, Higginson IJ, Wilcock A, Maddocks M
Cochrane Database Syst Rev 2016 Oct 17;10(10):CD009419. doi: 10.1002/14651858.CD009419.pub3. PMID: 27748503Free PMC Article
Neuromuscular electrical stimulation for muscle weakness in adults with advanced disease.
Maddocks M, Gao W, Higginson IJ, Wilcock A
Cochrane Database Syst Rev 2013 Jan 31;(1):CD009419. doi: 10.1002/14651858.CD009419.pub2. PMID: 23440837

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