U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Vaginal carcinoma

MedGen UID:
82653
Concept ID:
C0262659
Neoplastic Process
Synonyms: Cancer of the Vagina; Cancer of Vagina; Carcinoma of the Vagina; carcinoma of the vagina; Carcinoma of vagina; Carcinoma of Vagina; carcinoma of vagina; Vagina Cancer; Vagina Carcinoma; vagina carcinoma; Vaginal Cancer; Vaginal Carcinoma; vaginal carcinoma; Vaginal malignant epithelial tumor
SNOMED CT: Carcinoma of vagina (254893005)
 
Monarch Initiative: MONDO:0015867
Orphanet: ORPHA180247

Definition

A group of rare vaginal tumors comprising HPV-associated and HPV-independent squamous cell carcinoma, glandular tumors (including HPV-associated adenocarcinoma, endometrioid carcinoma, clear cell carcinoma, gastric type and intestinal type mucinous carcinoma, and mesonephric adenocarcinoma), adenocarcinoma of Skene gland origin, adenosquamous carcinoma, and adenoid basal carcinoma. Depending on the type of tumor and disease stage, patients may present with symptoms related to a vaginal mass, vaginal bleeding and/or discharge, postcoital bleeding, urinary symptoms, pelvic pain, and a foreign body sensation within the vagina. [from ORDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVVaginal carcinoma
Follow this link to review classifications for Vaginal carcinoma in Orphanet.

Professional guidelines

PubMed

Liu S, Li M, Zhang H
Asian J Surg 2024 Apr;47(4):2039-2040. Epub 2024 Jan 13 doi: 10.1016/j.asjsur.2024.01.030. PMID: 38220528
Kulkarni A, Dogra N, Zigras T
Curr Oncol 2022 Apr 27;29(5):3082-3092. doi: 10.3390/curroncol29050250. PMID: 35621640Free PMC Article
Woodruff JD, Parmley TH, Julian CG
Gynecol Oncol 1975 Jun;3(2):124-32. doi: 10.1016/0090-8258(75)90073-6. PMID: 1183865

Recent clinical studies

Etiology

Rountis A, Pergialiotis V, Tsetsa P, Rodolakis A, Haidopoulos D
Int J Clin Pract 2020 Nov;74(11):e13598. Epub 2020 Aug 4 doi: 10.1111/ijcp.13598. PMID: 32602195
Gadducci A, Fabrini MG, Lanfredini N, Sergiampietri C
Crit Rev Oncol Hematol 2015 Mar;93(3):211-24. Epub 2014 Oct 5 doi: 10.1016/j.critrevonc.2014.09.002. PMID: 25476235
Di Donato V, Bellati F, Fischetti M, Plotti F, Perniola G, Panici PB
Crit Rev Oncol Hematol 2012 Mar;81(3):286-95. Epub 2011 May 14 doi: 10.1016/j.critrevonc.2011.04.004. PMID: 21571543
Cormio G, Di Vagno G, Loverro G, Selvaggi L
Arch Gynecol Obstet 1993;253(3):145-7. doi: 10.1007/BF02767332. PMID: 8250602
Aho M, Vesterinen E, Meyer B, Purola E, Paavonen J
Cancer 1991 Jul 1;68(1):195-7. doi: 10.1002/1097-0142(19910701)68:1<195::aid-cncr2820680135>3.0.co;2-l. PMID: 2049744

Diagnosis

Ahmed W, Zaib S, Ullah S, Fatima A, Zaib Z, Haseeb Azam MA, Umar U, Tariq MU, Aslam R, Khan I
Mini Rev Med Chem 2023;23(10):1079-1089. doi: 10.2174/1389557523666230213140641. PMID: 36788701
Garganese G, Romito A, Scambia G, Fagotti A
Curr Opin Oncol 2021 Sep 1;33(5):485-492. doi: 10.1097/CCO.0000000000000757. PMID: 34319290
Lutz MH, Underwood PB Jr, Rozier JC, Putney FW
Am J Obstet Gynecol 1977 Nov 1;129(5):536-42. PMID: 562068
Merchant S, Murad TM, Dowling EA, Durant J
Acta Cytol 1974 Nov-Dec;18(6):494-503. PMID: 4531803
McIndoe WA, Green GH
Acta Cytol 1969 Mar;13(3):158-62. PMID: 5253726

Therapy

Rountis A, Pergialiotis V, Tsetsa P, Rodolakis A, Haidopoulos D
Int J Clin Pract 2020 Nov;74(11):e13598. Epub 2020 Aug 4 doi: 10.1111/ijcp.13598. PMID: 32602195
Di Donato V, Bellati F, Fischetti M, Plotti F, Perniola G, Panici PB
Crit Rev Oncol Hematol 2012 Mar;81(3):286-95. Epub 2011 May 14 doi: 10.1016/j.critrevonc.2011.04.004. PMID: 21571543
Grigsby PW
Curr Treat Options Oncol 2002 Apr;3(2):125-30. doi: 10.1007/s11864-002-0058-4. PMID: 12057075
Katib S, Kuten A, Steiner M, Yudelev M, Robinson E
Gynecol Oncol 1985 May;21(1):101-2. doi: 10.1016/0090-8258(85)90238-0. PMID: 2580757
Woodruff JD, Parmley TH, Julian CG
Gynecol Oncol 1975 Jun;3(2):124-32. doi: 10.1016/0090-8258(75)90073-6. PMID: 1183865

Prognosis

Gadducci A, Fabrini MG, Lanfredini N, Sergiampietri C
Crit Rev Oncol Hematol 2015 Mar;93(3):211-24. Epub 2014 Oct 5 doi: 10.1016/j.critrevonc.2014.09.002. PMID: 25476235
Bradley KA, Petereit DG
Hematol Oncol Clin North Am 2006 Apr;20(2):347-61. doi: 10.1016/j.hoc.2006.01.019. PMID: 16730298
Cormio G, Di Vagno G, Loverro G, Selvaggi L
Arch Gynecol Obstet 1993;253(3):145-7. doi: 10.1007/BF02767332. PMID: 8250602
Aho M, Vesterinen E, Meyer B, Purola E, Paavonen J
Cancer 1991 Jul 1;68(1):195-7. doi: 10.1002/1097-0142(19910701)68:1<195::aid-cncr2820680135>3.0.co;2-l. PMID: 2049744
Ball HG, Berman ML
Gynecol Oncol 1982 Oct;14(2):154-63. doi: 10.1016/0090-8258(82)90085-3. PMID: 7129211

Clinical prediction guides

Garganese G, Romito A, Scambia G, Fagotti A
Curr Opin Oncol 2021 Sep 1;33(5):485-492. doi: 10.1097/CCO.0000000000000757. PMID: 34319290
Kim MK, Lee IH, Lee KH
J Gynecol Oncol 2018 Jan;29(1):e6. doi: 10.3802/jgo.2018.29.e6. PMID: 29185264Free PMC Article
Gadducci A, Fabrini MG, Lanfredini N, Sergiampietri C
Crit Rev Oncol Hematol 2015 Mar;93(3):211-24. Epub 2014 Oct 5 doi: 10.1016/j.critrevonc.2014.09.002. PMID: 25476235
Dittmer C, Katalinic A, Mundhenke C, Thill M, Fischer D
Arch Gynecol Obstet 2011 Jul;284(1):169-74. Epub 2011 Feb 22 doi: 10.1007/s00404-011-1850-9. PMID: 21340687
Kirkbride P, Fyles A, Rawlings GA, Manchul L, Levin W, Murphy KJ, Simm J
Gynecol Oncol 1995 Mar;56(3):435-43. doi: 10.1006/gyno.1995.1077. PMID: 7705681

Recent systematic reviews

Frigerio M, Inzoli A, Barba M
Int J Gynaecol Obstet 2022 Nov;159(2):365-371. Epub 2022 Feb 28 doi: 10.1002/ijgo.14137. PMID: 35167139
Bryan S, Barbara C, Thomas J, Olaitan A
BMC Womens Health 2019 Jan 7;19(1):3. doi: 10.1186/s12905-018-0707-9. PMID: 30616555Free PMC Article
Guerri S, Perrone AM, Buwenge M, Ferioli M, Macchia G, Tagliaferri L, Ferrandina G, Galuppi A, Andrulli AD, Frakulli R, Cammelli S, Arcelli A, De Iaco P, Morganti AG
Oncologist 2019 Jan;24(1):132-141. Epub 2018 Aug 23 doi: 10.1634/theoncologist.2017-0546. PMID: 30139838Free PMC Article
Tranoulis A, Laios A, Mitsopoulos V, Lutchman-Singh K, Thomakos N
Eur J Obstet Gynecol Reprod Biol 2017 Nov;218:129-136. Epub 2017 Sep 27 doi: 10.1016/j.ejogrb.2017.09.020. PMID: 28985547

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...