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Metastatic Colorectal Carcinoma

MedGen UID:
1662385
•Concept ID:
C4744564
•
Neoplastic Process

Definition

A carcinoma that arises from the colon or rectum and has metastasized to another anatomic site. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMetastatic Colorectal Carcinoma

Professional guidelines

PubMed

Bevacizumab treatment in metastatic colorectal carcinoma - an economic perspective.
Sehnalová I, Říhová B, Demlová R
Ceska Slov Farm 2019 Summer;68(2):43-47. PMID: 31331174
Extended RAS Gene Mutation Testing in Metastatic Colorectal Carcinoma to Predict Response to Anti-Epidermal Growth Factor Receptor Monoclonal Antibody Therapy: American Society of Clinical Oncology Provisional Clinical Opinion Update 2015 Summary.
Allegra CJ, Rumble RB, Schilsky RL
J Oncol Pract 2016 Feb;12(2):180-1. Epub 2015 Oct 6 doi: 10.1200/JOP.2015.007898. PMID: 26443838
Treatment of metastatic colorectal carcinoma with 5-fluorouracil by mouth.
Lahiri SR, Boileau G, Hall TC
Cancer 1971 Oct;28(4):902-6. doi: 10.1002/1097-0142(1971)28:4<902::aid-cncr2820280413>3.0.co;2-r. PMID: 5111742

Recent clinical studies

Etiology

Construction and validation of nomograms combined with novel machine learning algorithms to predict early death of patients with metastatic colorectal cancer.
Zhang Y, Zhang Z, Wei L, Wei S
Front Public Health 2022;10:1008137. Epub 2022 Dec 20 doi: 10.3389/fpubh.2022.1008137. PMID: 36605237Free PMC Article
Management of Metastatic Colorectal Carcinoma in Older Adults: Balancing Risks and Benefits of Novel Therapies.
Correa E, Lindsay T, Dotan E
Drugs Aging 2021 Aug;38(8):639-654. Epub 2021 Jun 18 doi: 10.1007/s40266-021-00869-z. PMID: 34143421Free PMC Article
Bevacizumab treatment in metastatic colorectal carcinoma - an economic perspective.
Sehnalová I, Říhová B, Demlová R
Ceska Slov Farm 2019 Summer;68(2):43-47. PMID: 31331174
Ramucirumab versus placebo in combination with second-line FOLFIRI in patients with metastatic colorectal carcinoma that progressed during or after first-line therapy with bevacizumab, oxaliplatin, and a fluoropyrimidine (RAISE): a randomised, double-blind, multicentre, phase 3 study.
Tabernero J, Yoshino T, Cohn AL, Obermannova R, Bodoky G, Garcia-Carbonero R, Ciuleanu TE, Portnoy DC, Van Cutsem E, Grothey A, Prausová J, Garcia-Alfonso P, Yamazaki K, Clingan PR, Lonardi S, Kim TW, Simms L, Chang SC, Nasroulah F; RAISE Study Investigators
Lancet Oncol 2015 May;16(5):499-508. Epub 2015 Apr 12 doi: 10.1016/S1470-2045(15)70127-0. PMID: 25877855
Randomized clinical trials in advanced and metastatic colorectal carcinoma.
Dangelica MI, Shoup MC, Nissan A
Surg Oncol Clin N Am 2002 Jan;11(1):173-91, ix. doi: 10.1016/s1055-3207(03)00080-2. PMID: 11928799

Diagnosis

Construction and validation of nomograms combined with novel machine learning algorithms to predict early death of patients with metastatic colorectal cancer.
Zhang Y, Zhang Z, Wei L, Wei S
Front Public Health 2022;10:1008137. Epub 2022 Dec 20 doi: 10.3389/fpubh.2022.1008137. PMID: 36605237Free PMC Article
ChIP-seq of plasma cell-free nucleosomes identifies gene expression programs of the cells of origin.
Sadeh R, Sharkia I, Fialkoff G, Rahat A, Gutin J, Chappleboim A, Nitzan M, Fox-Fisher I, Neiman D, Meler G, Kamari Z, Yaish D, Peretz T, Hubert A, Cohen JE, Salah A, Temper M, Grinshpun A, Maoz M, Abu-Gazala S, Ben Ya'acov A, Shteyer E, Safadi R, Kaplan T, Shemer R, Planer D, Galun E, Glaser B, Zick A, Dor Y, Friedman N
Nat Biotechnol 2021 May;39(5):586-598. Epub 2021 Jan 11 doi: 10.1038/s41587-020-00775-6. PMID: 33432199Free PMC Article
Recommendations for SIR-Spheres Y-90 resin microspheres in chemotherapy-refractory/intolerant colorectal liver metastases.
Aranda E, Aparicio J, Bilbao JI, García-Alfonso P, Maurel J, Rodríguez J, Sangro B, Vieitez JM, Feliu J
Future Oncol 2017 Oct;13(23):2065-2082. Epub 2017 Jul 13 doi: 10.2217/fon-2017-0220. PMID: 28703622
Hepatocellular carcinoma and nodular regenerative hyperplasia after chemotherapy for metastatic colorectal carcinoma.
Calderaro J, Azoulay D, Zafrani ES
Hepatology 2014 Oct;60(4):1440-1. Epub 2014 Apr 29 doi: 10.1002/hep.27115. PMID: 24604623
Pulmonary enteric adenocarcinoma indistinguishable morphologically and immunohistologically from metastatic colorectal carcinoma.
László T, Lacza A, Tóth D, Molnár TF, Kálmán E
Histopathology 2014 Aug;65(2):283-7. Epub 2014 Apr 23 doi: 10.1111/his.12403. PMID: 24571601

Therapy

Construction and validation of nomograms combined with novel machine learning algorithms to predict early death of patients with metastatic colorectal cancer.
Zhang Y, Zhang Z, Wei L, Wei S
Front Public Health 2022;10:1008137. Epub 2022 Dec 20 doi: 10.3389/fpubh.2022.1008137. PMID: 36605237Free PMC Article
Ramucirumab versus placebo in combination with second-line FOLFIRI in patients with metastatic colorectal carcinoma that progressed during or after first-line therapy with bevacizumab, oxaliplatin, and a fluoropyrimidine (RAISE): a randomised, double-blind, multicentre, phase 3 study.
Tabernero J, Yoshino T, Cohn AL, Obermannova R, Bodoky G, Garcia-Carbonero R, Ciuleanu TE, Portnoy DC, Van Cutsem E, Grothey A, Prausová J, Garcia-Alfonso P, Yamazaki K, Clingan PR, Lonardi S, Kim TW, Simms L, Chang SC, Nasroulah F; RAISE Study Investigators
Lancet Oncol 2015 May;16(5):499-508. Epub 2015 Apr 12 doi: 10.1016/S1470-2045(15)70127-0. PMID: 25877855
Locoregional therapies for metastatic colorectal carcinoma to the liver--an evidence-based review.
Xing M, Kooby DA, El-Rayes BF, Kokabi N, Camacho JC, Kim HS
J Surg Oncol 2014 Aug;110(2):182-96. Epub 2014 Apr 24 doi: 10.1002/jso.23619. PMID: 24760444
Panitumumab (vectibix).
Gemmete JJ, Mukherji SK
AJNR Am J Neuroradiol 2011 Jun-Jul;32(6):1002-3. Epub 2011 May 19 doi: 10.3174/ajnr.A2601. PMID: 21596817Free PMC Article
Role of leucovorin dosing and administration schedule.
Jolivet J
Eur J Cancer 1995 Jul-Aug;31A(7-8):1311-5. doi: 10.1016/0959-8049(95)00140-e. PMID: 7577042

Prognosis

Construction and validation of nomograms combined with novel machine learning algorithms to predict early death of patients with metastatic colorectal cancer.
Zhang Y, Zhang Z, Wei L, Wei S
Front Public Health 2022;10:1008137. Epub 2022 Dec 20 doi: 10.3389/fpubh.2022.1008137. PMID: 36605237Free PMC Article
Sarcopenia in Metastatic Colorectal Carcinoma.
Büchler T, Hornová J
Klin Onkol 2019 Fall;32(6):406-410. doi: 10.14735/amko2019406. PMID: 31842559
Extended RAS Gene Mutation Testing in Metastatic Colorectal Carcinoma to Predict Response to Anti-Epidermal Growth Factor Receptor Monoclonal Antibody Therapy: American Society of Clinical Oncology Provisional Clinical Opinion Update 2015 Summary.
Allegra CJ, Rumble RB, Schilsky RL
J Oncol Pract 2016 Feb;12(2):180-1. Epub 2015 Oct 6 doi: 10.1200/JOP.2015.007898. PMID: 26443838
Pharmacogenomics of cetuximab in metastatic colorectal carcinoma.
Silvestris N, Vincenzi B, Brunetti AE, Loupakis F, Dell'Aquila E, Russo A, Scartozzi M, Giampieri R, Cascinu S, Lorusso V, Tonini G, Falcone A, Santini D
Pharmacogenomics 2014 Sep;15(13):1701-15. doi: 10.2217/pgs.14.124. PMID: 25410895
Palliation of hepatic tumors.
Cunningham SC, Choti MA, Bellavance EC, Pawlik TM
Surg Oncol 2007 Dec;16(4):277-91. Epub 2007 Nov 1 doi: 10.1016/j.suronc.2007.08.010. PMID: 17935975

Clinical prediction guides

Construction and validation of nomograms combined with novel machine learning algorithms to predict early death of patients with metastatic colorectal cancer.
Zhang Y, Zhang Z, Wei L, Wei S
Front Public Health 2022;10:1008137. Epub 2022 Dec 20 doi: 10.3389/fpubh.2022.1008137. PMID: 36605237Free PMC Article
Sarcopenia in Metastatic Colorectal Carcinoma.
Büchler T, Hornová J
Klin Onkol 2019 Fall;32(6):406-410. doi: 10.14735/amko2019406. PMID: 31842559
Extended RAS Gene Mutation Testing in Metastatic Colorectal Carcinoma to Predict Response to Anti-Epidermal Growth Factor Receptor Monoclonal Antibody Therapy: American Society of Clinical Oncology Provisional Clinical Opinion Update 2015 Summary.
Allegra CJ, Rumble RB, Schilsky RL
J Oncol Pract 2016 Feb;12(2):180-1. Epub 2015 Oct 6 doi: 10.1200/JOP.2015.007898. PMID: 26443838
Pharmacogenomics of cetuximab in metastatic colorectal carcinoma.
Silvestris N, Vincenzi B, Brunetti AE, Loupakis F, Dell'Aquila E, Russo A, Scartozzi M, Giampieri R, Cascinu S, Lorusso V, Tonini G, Falcone A, Santini D
Pharmacogenomics 2014 Sep;15(13):1701-15. doi: 10.2217/pgs.14.124. PMID: 25410895
Oncosurgery: a new reality in metastatic colorectal carcinoma.
Topham C, Adam R
Semin Oncol 2002 Oct;29(5 Suppl 15):3-10. doi: 10.1053/sonc.2002.35526. PMID: 12422303

Recent systematic reviews

Combining Selective Internal Radiation Therapy with Immunotherapy in Treating Hepatocellular Carcinoma and Hepatic Colorectal Metastases: A Systematic Review.
Ramdhani K, Smits MLJ, Lam MGEH, Braat AJAT
Cancer Biother Radiopharm 2023 May;38(4):216-224. Epub 2023 Jan 2 doi: 10.1089/cbr.2022.0071. PMID: 36595357
Comparison of Regorafenib, Fruquintinib, and TAS-102 in Previously Treated Patients with Metastatic Colorectal Cancer: A Systematic Review and Network Meta-Analysis of Five Clinical Trials.
Chen J, Wang J, Lin H, Peng Y
Med Sci Monit 2019 Dec 2;25:9179-9191. doi: 10.12659/MSM.918411. PMID: 31790382Free PMC Article
Comparison of efficacy and safety of S-1 and capecitabine in patients with metastatic colorectal carcinoma: A systematic review and meta-analysis.
Chen J, Wang J, Xu T
Medicine (Baltimore) 2019 Jul;98(30):e16667. doi: 10.1097/MD.0000000000016667. PMID: 31348323Free PMC Article
Update review of skin adverse events during treatment of lung cancer and colorectal carcinoma with epidermal growth receptor factor inhibitors.
Peng Y, Li Q, Zhang J, Shen W, Zhang X, Sun C, Cui H
Biosci Trends 2019 Jan 22;12(6):537-552. Epub 2018 Dec 17 doi: 10.5582/bst.2018.01246. PMID: 30555112
Extended RAS Gene Mutation Testing in Metastatic Colorectal Carcinoma to Predict Response to Anti-Epidermal Growth Factor Receptor Monoclonal Antibody Therapy: American Society of Clinical Oncology Provisional Clinical Opinion Update 2015.
Allegra CJ, Rumble RB, Hamilton SR, Mangu PB, Roach N, Hantel A, Schilsky RL
J Clin Oncol 2016 Jan 10;34(2):179-85. Epub 2015 Oct 5 doi: 10.1200/JCO.2015.63.9674. PMID: 26438111

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