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    Cacna1b calcium voltage-gated channel subunit alpha1 B [ Heterocephalus glaber (naked mole-rat) ]

    Gene ID: 101697609, updated on 3-Dec-2024

    Summary

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    Gene symbol
    Cacna1b
    Gene description
    calcium voltage-gated channel subunit alpha1 B
    See related
    Ensembl:ENSHGLG00000012917
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Heterocephalus glaber
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae; Heterocephalus
    Orthologs
    human mouse all
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    Genomic context

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    See Cacna1b in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    50
    Annotation release Status Assembly Chr Location
    102 current HetGla_female_1.0 (GCF_000247695.1) Unplaced Scaffold NW_004624760.1 (78754..257901, complement)

    NW_004624760.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC106009765 Neighboring gene uncharacterized LOC110350111 Neighboring gene euchromatic histone lysine methyltransferase 1 Neighboring gene cytoplasmic polyadenylation element-binding protein 1 pseudogene

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_004624760 Unplaced Scaffold Reference HetGla_female_1.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables high voltage-gated calcium channel activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in calcium ion import across plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in chemical synaptic transmission IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in neuronal cell body IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of voltage-gated calcium channel complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    voltage-dependent N-type calcium channel subunit alpha-1B

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Heterocephalus glaber Annotation Release 102 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference HetGla_female_1.0 Primary Assembly

    Genomic

    1. NW_004624760.1 Reference HetGla_female_1.0 Primary Assembly

      Range
      78754..257901 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021261576.1 → XP_021117235.1  voltage-dependent N-type calcium channel subunit alpha-1B isoform X8

      UniProtKB/TrEMBL
      A0AAX6TBQ3, G5BG05
      Conserved Domains (5) summary
      pfam00520
      Location:1509 → 1758
      Ion_trans; Ion transport protein
      pfam08763
      Location:1832 → 1906
      Ca_chan_IQ; Voltage gated calcium channel IQ domain
      pfam16905
      Location:1759 → 1830
      GPHH; Voltage-dependent L-type calcium channel, IQ-associated
      cl25836
      Location:2024 → 2328
      Retinal; Retinal protein
      cl28310
      Location:877 → 1056
      Rho; Transcription termination factor Rho [Transcription]

    2. XM_021261579.1 → XP_021117238.1  voltage-dependent N-type calcium channel subunit alpha-1B isoform X12

      UniProtKB/TrEMBL
      A0AAX6TAX1, G5BG05
      Conserved Domains (5) summary
      PHA03169
      Location:877 → 1124
      PHA03169; hypothetical protein; Provisional
      pfam00520
      Location:1475 → 1724
      Ion_trans; Ion transport protein
      pfam08763
      Location:1798 → 1872
      Ca_chan_IQ; Voltage gated calcium channel IQ domain
      pfam16905
      Location:1725 → 1796
      GPHH; Voltage-dependent L-type calcium channel, IQ-associated
      cl25836
      Location:1990 → 2294
      Retinal; Retinal protein

    3. XM_021261573.1 → XP_021117232.1  voltage-dependent N-type calcium channel subunit alpha-1B isoform X3

      UniProtKB/TrEMBL
      A0AAX6TBD8, G5BG05
      Conserved Domains (5) summary
      pfam00520
      Location:1520 → 1769
      Ion_trans; Ion transport protein
      pfam08763
      Location:1843 → 1917
      Ca_chan_IQ; Voltage gated calcium channel IQ domain
      pfam16905
      Location:1770 → 1841
      GPHH; Voltage-dependent L-type calcium channel, IQ-associated
      cl25836
      Location:2035 → 2339
      Retinal; Retinal protein
      cl28310
      Location:888 → 1067
      Rho; Transcription termination factor Rho [Transcription]

    4. XM_021261575.1 → XP_021117234.1  voltage-dependent N-type calcium channel subunit alpha-1B isoform X7

      UniProtKB/TrEMBL
      A0AAX6T6R3, G5BG05
      Conserved Domains (5) summary
      pfam00520
      Location:1510 → 1759
      Ion_trans; Ion transport protein
      pfam08763
      Location:1833 → 1907
      Ca_chan_IQ; Voltage gated calcium channel IQ domain
      pfam16905
      Location:1760 → 1831
      GPHH; Voltage-dependent L-type calcium channel, IQ-associated
      cl25836
      Location:2025 → 2329
      Retinal; Retinal protein
      cl28310
      Location:878 → 1057
      Rho; Transcription termination factor Rho [Transcription]

    5. XM_021261577.1 → XP_021117236.1  voltage-dependent N-type calcium channel subunit alpha-1B isoform X10

      UniProtKB/TrEMBL
      A0AAX6T7J8, G5BG05
      Conserved Domains (6) summary
      pfam06390
      Location:801 → 1016
      NESP55; Neuroendocrine-specific golgi protein P55 (NESP55)
      PHA03169
      Location:901 → 1148
      PHA03169; hypothetical protein; Provisional
      pfam00520
      Location:1499 → 1748
      Ion_trans; Ion transport protein
      pfam08763
      Location:1822 → 1896
      Ca_chan_IQ; Voltage gated calcium channel IQ domain
      pfam16905
      Location:1749 → 1820
      GPHH; Voltage-dependent L-type calcium channel, IQ-associated
      cl25836
      Location:2014 → 2318
      Retinal; Retinal protein

    6. XM_013073643.2 → XP_012929097.1  voltage-dependent N-type calcium channel subunit alpha-1B isoform X9

      UniProtKB/TrEMBL
      A0AAX6QYI3, G5BG05
      Conserved Domains (4) summary
      pfam06390
      Location:799 → 1017
      NESP55; Neuroendocrine-specific golgi protein P55 (NESP55)
      pfam00520
      Location:1518 → 1749
      Ion_trans; Ion transport protein
      pfam08763
      Location:1823 → 1897
      Ca_chan_IQ; Voltage gated calcium channel IQ domain
      pfam16905
      Location:1757 → 1821
      GPHH; Voltage-dependent L-type calcium channel, IQ-associated

    7. XM_021261572.1 → XP_021117231.1  voltage-dependent N-type calcium channel subunit alpha-1B isoform X2

      UniProtKB/TrEMBL
      A0AAX6T9X0, G5BG05
      Conserved Domains (6) summary
      pfam06390
      Location:826 → 1037
      NESP55; Neuroendocrine-specific golgi protein P55 (NESP55)
      PHA03169
      Location:922 → 1169
      PHA03169; hypothetical protein; Provisional
      pfam00520
      Location:1520 → 1769
      Ion_trans; Ion transport protein
      pfam08763
      Location:1843 → 1917
      Ca_chan_IQ; Voltage gated calcium channel IQ domain
      pfam16905
      Location:1770 → 1841
      GPHH; Voltage-dependent L-type calcium channel, IQ-associated
      cl25836
      Location:2035 → 2339
      Retinal; Retinal protein

    8. XM_013073642.2 → XP_012929096.1  voltage-dependent N-type calcium channel subunit alpha-1B isoform X6

      UniProtKB/TrEMBL
      A0AAX6QXW2, G5BG05
      Conserved Domains (3) summary
      pfam00520
      Location:1535 → 1764
      Ion_trans; Ion transport protein
      pfam08763
      Location:1838 → 1912
      Ca_chan_IQ; Voltage gated calcium channel IQ domain
      pfam16905
      Location:1772 → 1836
      GPHH; Voltage-dependent L-type calcium channel, IQ-associated

    9. XM_013073641.2 → XP_012929095.1  voltage-dependent N-type calcium channel subunit alpha-1B isoform X5

      UniProtKB/TrEMBL
      A0AAX6QXQ8, G5BG05
      Conserved Domains (3) summary
      pfam00520
      Location:1535 → 1766
      Ion_trans; Ion transport protein
      pfam08763
      Location:1840 → 1914
      Ca_chan_IQ; Voltage gated calcium channel IQ domain
      pfam16905
      Location:1774 → 1838
      GPHH; Voltage-dependent L-type calcium channel, IQ-associated

    10. XM_013073640.2 → XP_012929094.1  voltage-dependent N-type calcium channel subunit alpha-1B isoform X4

      UniProtKB/TrEMBL
      A0AAX6QWW5, G5BG05
      Conserved Domains (3) summary
      pfam00520
      Location:1539 → 1768
      Ion_trans; Ion transport protein
      pfam08763
      Location:1842 → 1916
      Ca_chan_IQ; Voltage gated calcium channel IQ domain
      pfam16905
      Location:1776 → 1840
      GPHH; Voltage-dependent L-type calcium channel, IQ-associated

    11. XM_013073639.2 → XP_012929093.1  voltage-dependent N-type calcium channel subunit alpha-1B isoform X1

      UniProtKB/TrEMBL
      A0AAX6QW00, G5BG05
      Conserved Domains (3) summary
      pfam00520
      Location:1539 → 1770
      Ion_trans; Ion transport protein
      pfam08763
      Location:1844 → 1918
      Ca_chan_IQ; Voltage gated calcium channel IQ domain
      pfam16905
      Location:1778 → 1842
      GPHH; Voltage-dependent L-type calcium channel, IQ-associated

    12. XM_021261580.1 → XP_021117239.1  voltage-dependent N-type calcium channel subunit alpha-1B isoform X17

      UniProtKB/TrEMBL
      A0AAX6T9N6, G5BG05
      Conserved Domains (5) summary
      PHA03169
      Location:877 → 1124
      PHA03169; hypothetical protein; Provisional
      pfam00520
      Location:1471 → 1718
      Ion_trans; Ion transport protein
      pfam08763
      Location:1792 → 1866
      Ca_chan_IQ; Voltage gated calcium channel IQ domain
      pfam16905
      Location:1719 → 1790
      GPHH; Voltage-dependent L-type calcium channel, IQ-associated
      cl25836
      Location:1984 → 2288
      Retinal; Retinal protein

    13. XM_021261578.1 → XP_021117237.1  voltage-dependent N-type calcium channel subunit alpha-1B isoform X11

      UniProtKB/TrEMBL
      A0AAX6T4R0, G5BG05
      Conserved Domains (5) summary
      PHA03169
      Location:878 → 1125
      PHA03169; hypothetical protein; Provisional
      pfam00520
      Location:1476 → 1725
      Ion_trans; Ion transport protein
      pfam08763
      Location:1799 → 1873
      Ca_chan_IQ; Voltage gated calcium channel IQ domain
      pfam16905
      Location:1726 → 1797
      GPHH; Voltage-dependent L-type calcium channel, IQ-associated
      cl25836
      Location:1991 → 2295
      Retinal; Retinal protein

    14. XM_013073644.1 → XP_012929098.1  voltage-dependent N-type calcium channel subunit alpha-1B isoform X16

      UniProtKB/TrEMBL
      A0AAX6QZK9, G5BG05
      Conserved Domains (4) summary
      pfam06390
      Location:755 → 970
      NESP55; Neuroendocrine-specific golgi protein P55 (NESP55)
      pfam00520
      Location:1467 → 1698
      Ion_trans; Ion transport protein
      pfam08763
      Location:1772 → 1846
      Ca_chan_IQ; Voltage gated calcium channel IQ domain
      pfam16905
      Location:1706 → 1770
      GPHH; Voltage-dependent L-type calcium channel, IQ-associated

    15. XM_004848693.2 → XP_004848750.1  voltage-dependent N-type calcium channel subunit alpha-1B isoform X14

      UniProtKB/TrEMBL
      A0AAX6PD00, G5BG05
      Conserved Domains (4) summary
      pfam06390
      Location:753 → 971
      NESP55; Neuroendocrine-specific golgi protein P55 (NESP55)
      pfam00520
      Location:1468 → 1699
      Ion_trans; Ion transport protein
      pfam08763
      Location:1773 → 1847
      Ca_chan_IQ; Voltage gated calcium channel IQ domain
      pfam16905
      Location:1707 → 1771
      GPHH; Voltage-dependent L-type calcium channel, IQ-associated

    16. XM_004848692.2 → XP_004848749.1  voltage-dependent N-type calcium channel subunit alpha-1B isoform X13

      UniProtKB/TrEMBL
      A0AAX6PCZ7, G5BG05
      Conserved Domains (4) summary
      pfam06390
      Location:753 → 971
      NESP55; Neuroendocrine-specific golgi protein P55 (NESP55)
      pfam00520
      Location:1472 → 1701
      Ion_trans; Ion transport protein
      pfam08763
      Location:1775 → 1849
      Ca_chan_IQ; Voltage gated calcium channel IQ domain
      pfam16905
      Location:1709 → 1773
      GPHH; Voltage-dependent L-type calcium channel, IQ-associated

    17. XM_004848695.2 → XP_004848752.1  voltage-dependent N-type calcium channel subunit alpha-1B isoform X15

      UniProtKB/TrEMBL
      A0AAX6PCR0, G5BG05
      Related
      ENSHGLP00000018069.1, ENSHGLT00000018246.1
      Conserved Domains (4) summary
      pfam06390
      Location:754 → 972
      NESP55; Neuroendocrine-specific golgi protein P55 (NESP55)
      pfam00520
      Location:1469 → 1698
      Ion_trans; Ion transport protein
      pfam08763
      Location:1772 → 1846
      Ca_chan_IQ; Voltage gated calcium channel IQ domain
      pfam16905
      Location:1706 → 1770
      GPHH; Voltage-dependent L-type calcium channel, IQ-associated
    Nucleotide Protein
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