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    vvl ventral veins lacking [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 38752, updated on 9-Dec-2024

    Summary

    Official Symbol
    vvlprovided by FlyBase
    Official Full Name
    ventral veins lackingprovided by FlyBase
    Primary source
    FLYBASE:FBgn0086680
    Locus tag
    Dmel_CG10037
    See related
    AllianceGenome:FB:FBgn0086680
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Cf1-a; Cf1a; CF1A; Cf1a/drifter; Cf1a/drifter/vvl; Cfla; CG10037; dfr; Dfr; DFR; dfr-vvl; dfr/vvl; Dfr/Vvl; Dmel\CG10037; drf; Drf; prd3; sep; ut; Vv1; Vvl; VVL; vvl/dfr; vvl/dfr/ut
    Summary
    Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in nervous system development; positive regulation of macromolecule biosynthetic process; and regulation of dendrite morphogenesis. Located in nucleus. Is expressed in several structures, including adult optic lobe neurons; adult uniglomerular antennal lobe projection neuron lPN; epithelium; ganglia; and gut section. Human ortholog(s) of this gene implicated in X-linked deafness 2. Orthologous to several human genes including POU3F4 (POU class 3 homeobox 4). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See vvl in Genome Data Viewer
    Location:
    65C5-65C5; 3-17 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (6790158..6794941)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (6783258..6788041)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene Radial spoke head protein 3 Neighboring gene long non-coding RNA:CR45759 Neighboring gene long non-coding RNA:CR45115 Neighboring gene long non-coding RNA:CR45416

    Genomic regions, transcripts, and products

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Interactions

    General gene information

    Gene Ontology Provided by FlyBase

    Component Evidence Code Pubs
    located_in nucleus PubMed 
    located_in nucleus  

    General protein information

    Preferred Names
    ventral veins lacking
    Names
    CG10037-PA
    CG10037-PC
    CG10037-PD
    CG10037-PE
    CG10037-PF
    Drifter/Ventral veinless
    PRD gene 3
    U-turned
    drifter
    paired-like 3
    separated
    u-turn
    ventral veinless
    vvl-PA
    vvl-PC
    vvl-PD
    vvl-PE
    vvl-PF

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      6790158..6794941
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001300028.1 → NP_001286957.1  ventral veins lacking, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001286957.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P16241, Q24460, Q86P26, Q9VRY9
      UniProtKB/TrEMBL
      A8E6G8
      Conserved Domains (2) summary
      smart00352
      Location:212 → 286
      POU; Found in Pit-Oct-Unc transcription factors
      pfam00046
      Location:307 → 361
      Homeobox; Homeobox domain
    2. NM_079224.5 → NP_523948.1  ventral veins lacking, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_523948.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P16241, Q24460, Q86P26, Q9VRY9
      UniProtKB/TrEMBL
      A8E6G8
      Related
      FBpp0076653
      Conserved Domains (2) summary
      smart00352
      Location:212 → 286
      POU; Found in Pit-Oct-Unc transcription factors
      pfam00046
      Location:307 → 361
      Homeobox; Homeobox domain
    3. NM_001169884.2 → NP_001163355.2  ventral veins lacking, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001163355.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      E1JI48
      Conserved Domains (2) summary
      smart00352
      Location:212 → 286
      POU; Found in Pit-Oct-Unc transcription factors
      pfam00046
      Location:307 → 360
      Homeobox; Homeobox domain
    4. NM_001316454.1 → NP_001303383.1  ventral veins lacking, isoform E [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0S0WNN1
      Conserved Domains (2) summary
      smart00352
      Location:212 → 286
      POU; Found in Pit-Oct-Unc transcription factors
      pfam00046
      Location:307 → 360
      Homeobox; Homeobox domain
    5. NM_001316455.1 → NP_001303384.1  ventral veins lacking, isoform F [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0S0WGV5
      Conserved Domains (2) summary
      smart00352
      Location:212 → 286
      POU; Found in Pit-Oct-Unc transcription factors
      pfam00046
      Location:307 → 360
      Homeobox; Homeobox domain
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