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    CHZ1 Chz1p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 856752, updated on 4-Jan-2025

    Summary

    Official Symbol
    CHZ1
    Official Full Name
    Chz1p
    Primary source
    SGD:S000000832
    Locus tag
    YER030W
    See related
    AllianceGenome:SGD:S000000832; FungiDB:YER030W; VEuPathDB:YER030W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Enables histone binding activity. Involved in chromatin remodeling. Is active in nucleus. [provided by Alliance of Genome Resources, Jan 2025]
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    Genomic context

    See CHZ1 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    1
    Sequence:
    Chromosome: V; NC_001137.3 (213437..213898)

    Chromosome V - NC_001137.3Genomic Context describing neighboring genes Neighboring gene Mig3p Neighboring gene mRNA splicing protein SMB1 Neighboring gene Rab family GTPase YPT31 Neighboring gene Fir1p

    Bibliography

    Interactions

    General gene information

    Gene Ontology Provided by SGD

    Component Evidence Code Pubs
    is_active_in nucleus PubMed 
    is_active_in nucleus PubMed 
    located_in nucleus  

    General protein information

    Preferred Names
    Chz1p
    NP_010947.2
    • Histone chaperone for Htz1p/H2A-H2B dimer; required for the stabilization of the Chz1p-Htz1-H2B complex; has overlapping function with Nap1p; null mutant displays weak sensitivity to MMS and benomyl; contains a highly conserved CHZ motif; protein abundance increases in response to DNA replication stress

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001137.3 Reference assembly

      Range
      213437..213898
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001178921.1 → NP_010947.2  TPA: Chz1p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_010947.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D3DLS9, P40019
      UniProtKB/TrEMBL
      G2WCR3, N1P6V3
      Conserved Domains (1) summary
      pfam09649
      Location:97 → 120
      CHZ; Histone chaperone domain CHZ
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