The MG-U74 set includes 3 arrays with a total of 36899 entries and was indexed 29-Jan-2002. The set represents ~36,000 full length genes and EST clusters derived from sequence clusters in Build 74 of the Mouse Unigene Database.
June 03, 2009: annotation table updated with netaffx build 28 June 21, 2012: annotation table updated with netaffx build 32 July 06, 2016: annotation table updated with netaffx build 35
Combined analysis of oligonucleotide microarray data from transgenic and knockout mice identifies direct SREBP target genes
Data table header descriptions
ID
Affymetrix Probe Set ID
GB_ACC
GenBank Accession Number
SPOT_ID
identifies controls
Species Scientific Name
The genus and species of the organism represented by the probe set.
Annotation Date
The date that the annotations for this probe array were last updated. It will generally be earlier than the date when the annotations were posted on the Affymetrix web site.
Sequence Type
Sequence Source
The database from which the sequence used to design this probe set was taken.
Target Description
Representative Public ID
The accession number of a representative sequence. Note that for consensus-based probe sets, the representative sequence is only one of several sequences (sequence sub-clusters) used to build the consensus sequence and it is not directly used to derive the probe sequences. The representative sequence is chosen during array design as a sequence that is best associated with the transcribed region being interrogated by the probe set. Refer to the "Sequence Source" field to determine the database used.
Gene Title
Title of Gene represented by the probe set.
Gene Symbol
A gene symbol, when one is available (from UniGene).
ENTREZ_GENE_ID
Entrez Gene Database UID
RefSeq Transcript ID
References to multiple sequences in RefSeq. The field contains the ID and Description for each entry, and there can be multiple entries per ProbeSet.
Gene Ontology Biological Process
Gene Ontology Consortium Biological Process derived from LocusLink. Each annotation consists of three parts: "Accession Number // Description // Evidence". The description corresponds directly to the GO ID. The evidence can be "direct", or "extended".
Gene Ontology Cellular Component
Gene Ontology Consortium Cellular Component derived from LocusLink. Each annotation consists of three parts: "Accession Number // Description // Evidence". The description corresponds directly to the GO ID. The evidence can be "direct", or "extended".
Gene Ontology Molecular Function
Gene Ontology Consortium Molecular Function derived from LocusLink. Each annotation consists of three parts: "Accession Number // Description // Evidence". The description corresponds directly to the GO ID. The evidence can be "direct", or "extended".
0030835 // negative regulation of actin filament depolymerization // not recorded /// 0031529 // ruffle organization // not recorded /// 0051017 // actin filament bundle assembly // not recorded
0001725 // stress fiber // not recorded /// 0005737 // cytoplasm // not recorded /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // not recorded /// 0005925 // focal adhesion // not recorded /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0015629 // actin cytoskeleton // not recorded
0003779 // actin binding // inferred from electronic annotation /// 0003785 // actin monomer binding // not recorded /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051015 // actin filament binding // not recorded
0006184 // GTP catabolic process // inferred from direct assay /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0006935 // chemotaxis // inferred from direct assay /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from genetic interaction /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from genetic interaction /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0015031 // protein transport // inferred from electronic annotation /// 0030031 // cell projection assembly // inferred from direct assay /// 0030036 // actin cytoskeleton organization // inferred from direct assay /// 0030036 // actin cytoskeleton organization // not recorded /// 0045453 // bone resorption // not recorded /// 0060263 // regulation of respiratory burst // not recorded
0005622 // intracellular // inferred from electronic annotation /// 0005635 // nuclear envelope // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // not recorded
0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from direct assay /// 0005525 // GTP binding // inferred from electronic annotation
0006486 // protein glycosylation // inferred from electronic annotation /// 0006487 // protein N-linked glycosylation // inferred from direct assay /// 0006487 // protein N-linked glycosylation // inferred from mutant phenotype
0000139 // Golgi membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation
0008375 // acetylglucosaminyltransferase activity // inferred from mutant phenotype /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0030144 // alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity // inferred from mutant phenotype
0000122 // negative regulation of transcription from RNA polymerase II promoter // not recorded /// 0001829 // trophectodermal cell differentiation // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006417 // regulation of translation // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0010606 // positive regulation of cytoplasmic mRNA processing body assembly // not recorded /// 0031047 // gene silencing by RNA // inferred from electronic annotation /// 0033147 // negative regulation of intracellular estrogen receptor signaling pathway // not recorded /// 0048387 // negative regulation of retinoic acid receptor signaling pathway // not recorded /// 0060213 // positive regulation of nuclear-transcribed mRNA poly(A) tail shortening // not recorded /// 0090503 // RNA phosphodiester bond hydrolysis, exonucleolytic // not recorded /// 1900153 // positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // not recorded /// 2000036 // regulation of stem cell maintenance // inferred from mutant phenotype /// 2000036 // regulation of stem cell maintenance // not recorded
0000932 // cytoplasmic mRNA processing body // inferred from direct assay /// 0000932 // cytoplasmic mRNA processing body // not recorded /// 0005615 // extracellular space // not recorded /// 0005634 // nucleus // not recorded /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005778 // peroxisomal membrane // not recorded /// 0030014 // CCR4-NOT complex // not recorded
0004535 // poly(A)-specific ribonuclease activity // not recorded /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0030331 // estrogen receptor binding // not recorded /// 0042974 // retinoic acid receptor binding // not recorded /// 0044822 // poly(A) RNA binding // not recorded
0032259 // methylation // not recorded /// 0045216 // cell-cell junction organization // not recorded /// 0046498 // S-adenosylhomocysteine metabolic process // not recorded /// 0046500 // S-adenosylmethionine metabolic process // not recorded /// 0070830 // tight junction assembly // not recorded
0005829 // cytosol // not recorded /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // not recorded /// 0005911 // cell-cell junction // inferred from direct assay /// 0005911 // cell-cell junction // not recorded /// 0005923 // tight junction // inferred from direct assay /// 0005923 // tight junction // not recorded /// 0009986 // cell surface // not recorded /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from direct assay /// 0016327 // apicolateral plasma membrane // inferred from direct assay /// 0030054 // cell junction // not recorded /// 0030139 // endocytic vesicle // inferred from direct assay /// 0031410 // cytoplasmic vesicle // not recorded
0005198 // structural molecule activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008119 // thiopurine S-methyltransferase activity // not recorded /// 0008757 // S-adenosylmethionine-dependent methyltransferase activity // not recorded /// 0019904 // protein domain specific binding // not recorded
0008612 // peptidyl-lysine modification to peptidyl-hypusine // inferred from mutant phenotype /// 0042102 // positive regulation of T cell proliferation // inferred from mutant phenotype /// 0042593 // glucose homeostasis // inferred from mutant phenotype /// 0050983 // deoxyhypusine biosynthetic process from spermidine // not recorded /// 0051289 // protein homotetramerization // not recorded
0016740 // transferase activity // inferred from electronic annotation /// 0034038 // deoxyhypusine synthase activity // not recorded
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