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Status |
Public on Sep 13, 2006 |
Title |
Comparison of D. simulans/D. sechellia F1 male hybrid genome-wide expression values to pure-species parents |
Platform organism |
Drosophila melanogaster |
Sample organisms |
Drosophila sechellia; Drosophila simulans; Drosophila sechellia x Drosophila simulans |
Experiment type |
Expression profiling by array
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Summary |
Species often produce sterile hybrids early in their evolutionary divergence, and some evidence suggests that hybrid sterility may be associated with deviations or disruptions in gene expression. In support of this idea, many studies have shown that a high proportion of male-biased genes are underexpressed compared to non-sex-biased genes in sterile F1 male hybrids of Drosophila species. In this study, we examined and compared patterns of misexpression in 4 day old sterile male F1 hybrids of Drosophila simulans and its sibling species, D. sechellia. We analyzed hybrids using genome-wide D. melanogaster arrays from the Drosophila Genome Resource Center (DGRC). The results from a custom array (GPL4022) for this species pair, from the custom array and the genome-wide array for the D. simulans-D. mauritiana species pair, and from the larvae of these two species pairs using the custom array, are presented separately. Keywords: Comparison of pure-species Drosophila expression to hybrid expression
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Overall design |
We analyzed 11 arrays: 4 of sim-sec vs. sec, 4 of sim-sec vs. sim, and one each of self-hybridizations (sim vs. sim, sim-sec vs. sim-sec, sec vs. sec).
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Contributor(s) |
Moehring AJ, Noor MA |
Citation(s) |
17032727 |
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Submission date |
Aug 25, 2006 |
Last update date |
Jun 12, 2013 |
Contact name |
Amanda J. Moehring |
E-mail(s) |
[email protected]
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Organization name |
Duke University
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Department |
DCMB/Biology
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Lab |
Mohamed Noor
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Street address |
Box 91000
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City |
Durham |
State/province |
NC |
ZIP/Postal code |
27708 |
Country |
USA |
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Platforms (1) |
GPL3829 |
DGRC-D. melanogaster-DGRC1-15552-v4 |
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Samples (22)
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GSM130728 |
D. simulans pure-species adults, D. simulans pure-species adults, genome chip, replicate 1, Cy5 |
GSM130890 |
D. sechellia pure-species, D. sechellia pure-species adults, genome chip, replicate 1, Cy5 |
GSM130891 |
D. simulans/D. sechellia hybrids, D. sechellia pure-species adults, genome chip, replicate 1, Cy5 |
GSM130892 |
D. simulans/D. sechellia hybrids, D. sechellia pure-species adults, genome chip, replicate 2, Cy5 |
GSM130893 |
D. simulans/D. sechellia hybrids, D. sechellia pure-species adults, genome chip, replicate 3, Cy5 |
GSM130894 |
D. simulans/D. sechellia hybrids, D. sechellia pure-species adults, genome chip, replicate 4, Cy5 |
GSM130895 |
D. simulans/D. sechellia hybrids, D. simulans/D. sechellia hybrid adults, genome chip, replicate 1, Cy5 |
GSM130897 |
D. simulans/D. sechellia hybrids, D. simulans pure-species adults, genome chip, replicate 1, Cy5 |
GSM130898 |
D. simulans/D. sechellia hybrids, D. simulans pure-species adults, genome chip, replicate 2, Cy5 |
GSM130899 |
D. simulans/D. sechellia hybrids, D. simulans pure-species adults, genome chip, replicate 3, Cy5 |
GSM130900 |
D. simulans/D. sechellia hybrids, D. simulans pure-species adults, genome chip, replicate 4, Cy5 |
GSM135858 |
D. simulans pure-species adults, D. simulans pure-species adults, genome chip, replicate 1, Cy3 |
GSM135863 |
D. sechellia pure-species, D. sechellia pure-species adults, genome chip, replicate 1, Cy3 |
GSM135864 |
D. simulans/D. sechellia hybrids, D. sechellia pure-species adults, genome chip, replicate 1, Cy3 |
GSM135865 |
D. simulans/D. sechellia hybrids, D. sechellia pure-species adults, genome chip, replicate 2, Cy3 |
GSM135866 |
D. simulans/D. sechellia hybrids, D. sechellia pure-species adults, genome chip, replicate 3, Cy3 |
GSM135867 |
D. simulans/D. sechellia hybrids, D. sechellia pure-species adults, genome chip, replicate 4, Cy3 |
GSM135868 |
D. simulans/D. sechellia hybrids, D. simulans/D. sechellia hybrid adults, genome chip, replicate 1, Cy3 |
GSM135869 |
D. simulans/D. sechellia hybrids, D. simulans pure-species adults, genome chip, replicate 1, Cy3 |
GSM135870 |
D. simulans/D. sechellia hybrids, D. simulans pure-species adults, genome chip, replicate 2, Cy3 |
GSM135871 |
D. simulans/D. sechellia hybrids, D. simulans pure-species adults, genome chip, replicate 3, Cy3 |
GSM135872 |
D. simulans/D. sechellia hybrids, D. simulans pure-species adults, genome chip, replicate 4, Cy3 |
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This SubSeries is part of SuperSeries: |
GSE5655 |
Comparison of pure-species Drosophila expression to hybrid expression |
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Relations |
BioProject |
PRJNA104371 |
Supplementary data files not provided |
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