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Series GSE5607 Query DataSets for GSE5607
Status Public on Sep 13, 2006
Title Comparison of D. simulans/D. sechellia F1 male hybrid genome-wide expression values to pure-species parents
Platform organism Drosophila melanogaster
Sample organisms Drosophila sechellia; Drosophila simulans; Drosophila sechellia x Drosophila simulans
Experiment type Expression profiling by array
Summary Species often produce sterile hybrids early in their evolutionary divergence, and some evidence suggests that hybrid sterility may be associated with deviations or disruptions in gene expression. In support of this idea, many studies have shown that a high proportion of male-biased genes are underexpressed compared to non-sex-biased genes in sterile F1 male hybrids of Drosophila species. In this study, we examined and compared patterns of misexpression in 4 day old sterile male F1 hybrids of Drosophila simulans and its sibling species, D. sechellia. We analyzed hybrids using genome-wide D. melanogaster arrays from the Drosophila Genome Resource Center (DGRC). The results from a custom array (GPL4022) for this species pair, from the custom array and the genome-wide array for the D. simulans-D. mauritiana species pair, and from the larvae of these two species pairs using the custom array, are presented separately.
Keywords: Comparison of pure-species Drosophila expression to hybrid expression
 
Overall design We analyzed 11 arrays: 4 of sim-sec vs. sec, 4 of sim-sec vs. sim, and one each of self-hybridizations (sim vs. sim, sim-sec vs. sim-sec, sec vs. sec).
 
Contributor(s) Moehring AJ, Noor MA
Citation(s) 17032727
Submission date Aug 25, 2006
Last update date Jun 12, 2013
Contact name Amanda J. Moehring
E-mail(s) [email protected]
Organization name Duke University
Department DCMB/Biology
Lab Mohamed Noor
Street address Box 91000
City Durham
State/province NC
ZIP/Postal code 27708
Country USA
 
Platforms (1)
GPL3829 DGRC-D. melanogaster-DGRC1-15552-v4
Samples (22)
GSM130728 D. simulans pure-species adults, D. simulans pure-species adults, genome chip, replicate 1, Cy5
GSM130890 D. sechellia pure-species, D. sechellia pure-species adults, genome chip, replicate 1, Cy5
GSM130891 D. simulans/D. sechellia hybrids, D. sechellia pure-species adults, genome chip, replicate 1, Cy5
This SubSeries is part of SuperSeries:
GSE5655 Comparison of pure-species Drosophila expression to hybrid expression
Relations
BioProject PRJNA104371

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