GEO DataSets

(Submitter supplied) Investigation of whole genome gene expression level changes in a B. suis 1330 regA mutant, compared to the wild-type strain. The two-component system RegBA of Brucella suis plays a central role in the control of respiratory systems adapted to oxygen deficiency. The mutant strain is affected in long-term persistence in vitro (this study) and in chronic infection in vivo (Abdou, E et al. 2013, Infect.Immun. more...

Organism:

Brucella suis; Brucella suis 1330

Type:

Expression profiling by array

Platform:

GPL22261

6 Samples

Download data: CALLS, PAIR

(Submitter supplied) In the intracellular pathogen Brucella spp., the activation of the stringent response, a global regulatory network providing rapid adaptation to a variety of growth-affecting stress conditions such as nutrient deficiency, is essential for replication in the host. A single, bi-functional enzyme Rsh catalyzes synthesis and hydrolysis of the alarmone (p)ppGpp, responsible for differential gene expression under stringent conditions. more...

Organism:

Brucella suis 1330; Brucella melitensis

Type:

Expression profiling by array

Platform:

GPL7612

4 Samples

Download data: TXT

(Submitter supplied) To reveal the scope of the stk regulation and explore the differences in the regulatory roles of SC-19 and ∆stk, the global gene transcription profiles of the WT and ∆stk strains were determined by RNA-seq analysis.

Organism:

Streptococcus suis

Type:

Expression profiling by high throughput sequencing

Platform:

GPL22539

2 Samples

Download data: TXT

(Submitter supplied) Brucella suis infects macrophages and dendritic cells. Wild boars act as reservoirs and carriers of Brucella suis biovar 2, and there is evidence that wild boar can be the main source of infection for domestic pigs through the venereal route. Transmission through this route could be an important path for disesease dissemination. The result from this study will contribute to the overall understanding of the molecular pathogenic mechanisms involved during Brucella suis infection in European wild boar.

Organism:

Sus scrofa

Type:

Expression profiling by array

Platform:

GPL3533

6 Samples

Download data: CEL

(Submitter supplied) MucR is one of the few transcriptional regulatory proteins that has been linked to Brucella pathogenesis. We used custom-made Affymetrix B. abortus strain 2308 derived GeneChips to copare the gene expression properties of wild type and isogenic mucR mutant cells.

Organism:

Brucella abortus

Type:

Expression profiling by array

Platform:

GPL15577

4 Samples

Download data: CEL, CHP

(Submitter supplied) An experiment to test the equivalence of the Citrobacter rodentium RegA and E.Coli SMS 3-5 homologue

Organism:

Citrobacter rodentium

Type:

Expression profiling by array

Platform:

GPL7345

16 Samples

Download data: TXT

(Submitter supplied) Hfq is a bacterial Sm-like protein which serves as a post-transcriptional regulator of global gene expression. It has been shown to be involved in a wide range of cellular processes and pathways. To characterize the regulation roles of Hfq in Brucella melitensis, the in vitro hfq induction conditions simulating intracellular environments were firstly defined, and then, the transcriptome of the hfq mutant was compared to that of the wild type strain. more...

Organism:

Brucella melitensis bv. 1 str. 16M; Brucella melitensis

Type:

Expression profiling by array

Platform:

GPL11117

4 Samples

Download data: GPR

(Submitter supplied) Differential gene expression was analyzed between B. japonicum wild type (Bj110) and aceA mutant (BjΔaceA) exposed to desiccation stress to find AceA regulons under the culture condition.

Organism:

Bradyrhizobium japonicum; Bradyrhizobium diazoefficiens USDA 110

Type:

Expression profiling by array

Platform:

GPL5341

6 Samples

Download data: GPR

(Submitter supplied) Identification of the targets of RegA with and without bicarbonate stimulation by comparing RegA knockout to multicopy RegA transgenics. RegA is an AraC like transcription factor identified in a mutational screen for virulence genes in Citrobacter rodentium, an attaching and effacing pathogen that causes transmissible colonic hyperplasia in mice. This experiment compares the RegA null strain with a multicopy plasmid rescue of this null strain in the presence and absence of bicarbonate with the aim of identifying pathogenesis related genes related to the early and late stages of attachment and effacement. more...

Organism:

Citrobacter rodentium

Type:

Expression profiling by array

Platform:

GPL7345

8 Samples

Download data: TXT

(Submitter supplied) In Situ synthesis

Organism:

Citrobacter rodentium

3 Series

40 Samples

Download data

(Submitter supplied) Transcriptional profiling in Pseudomonas aeruginosa MPAO1 and its glyoxylate shunt gens transposon insertion mutants (aceA and glcB) was perfomed using microarray analysis with or without 1mM PQ treatment. Based on the gene expression, we investigated role of glyoxylate shunt in P. aeruginosa and found out pathway related with glyoxylate shunt under oxidative stress.

Organism:

Pseudomonas aeruginosa PAO1

Type:

Expression profiling by high throughput sequencing

Platform:

GPL21507

12 Samples

Download data: GPR

(Submitter supplied) We report the identification of new noncoding RNAs in Brucella suis 1330 and that are associated to the chaperone protein Hfq

Organism:

Brucella suis 1330

Type:

Expression profiling by high throughput sequencing

Platform:

GPL20974

2 Samples

Download data: GR

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Brucella ovis

Type:

Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing

Platform:

GPL33317

19 Samples

Download data

(Submitter supplied) A multi-layered structure known as the cell envelope separates the controlled interior of Gram-negative bacteria from a fluctuating physical and chemical environment. Transcription of genes that determine cell envelope structure and function is commonly controlled by a class of environmental regulators known as two-component signal transduction systems (TCS), which are comprised of 1) sensor histidine kinases and 2) response regulators. more...

Organism:

Brucella ovis

Type:

Expression profiling by high throughput sequencing

Platform:

GPL33317

9 Samples

Download data: XLSX

(Submitter supplied) A multi-layered structure known as the cell envelope separates the controlled interior of Gram-negative bacteria from a fluctuating physical and chemical environment. Transcription of genes that determine cell envelope structure and function is commonly controlled by a class of environmental regulators known as two-component signal transduction systems (TCS), which are comprised of 1) sensor histidine kinases and 2) response regulators. more...

Organism:

Brucella ovis

Type:

Genome binding/occupancy profiling by high throughput sequencing

Platform:

GPL33317

10 Samples

Download data: CSV