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TOH1 Toh1p [ Saccharomyces cerevisiae S288C ]

Gene ID: 853268, updated on 9-Dec-2024

Summary

Official Symbol
TOH1
Official Full Name
Toh1p
Primary source
SGD:S000003707
Locus tag
YJL171C
See related
AllianceGenome:SGD:S000003707; FungiDB:YJL171C; VEuPathDB:YJL171C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Predicted to enable hydrolase activity, acting on glycosyl bonds. Predicted to be involved in cell wall organization. Located in fungal-type cell wall. [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

See TOH1 in Genome Data Viewer
Location:
chromosome: X
Exon count:
1
Sequence:
Chromosome: X; NC_001142.9 (99704..100894, complement)

Chromosome X - NC_001142.9Genomic Context describing neighboring genes Neighboring gene Rfa3p Neighboring gene Gly-Xaa carboxypeptidase Neighboring gene Asg7p Neighboring gene histone methyltransferase SET2

Interactions

General gene information

Gene Ontology Provided by SGD

Process Evidence Code Pubs
involved_in biological_process  
involved_in cell wall organization  

General protein information

Preferred Names
Toh1p
NP_012364.2
  • GPI-anchored cell wall hypothetical protein; induced in response to cell wall damaging agents and by mutations in genes involved in cell wall biogenesis; sequence similarity to YBR162C/TOS1, a covalently bound cell wall protein; protein abundance increases in response to DNA replication stress

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001142.9 Reference assembly

    Range
    99704..100894 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001181604.2 → NP_012364.2  TPA: Toh1p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_012364.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VW17, P46992
    UniProtKB/TrEMBL
    A6ZQG2, B3LPV3, C7GRZ8, C8ZB48, G2WGK3, N1P1E2
    Conserved Domains (2) summary
    pfam10287
    Location:107 → 336
    DUF2401; Putative TOS1-like glycosyl hydrolase (DUF2401)
    pfam10290
    Location:27 → 90
    DUF2403; Glycine-rich protein domain (DUF2403)
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