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Neurologic Manifestations

MedGen UID:
18017
Concept ID:
C0027854
Finding
Synonyms: Manifestation, Neurologic; Manifestation, Neurological; Manifestations, Neurologic; Manifestations, Neurological; Neurologic Manifestation; Neurologic Signs and Symptoms; Neurological Manifestation; Neurological Manifestations

Definition

Clinical signs and symptoms caused by nervous system injury or dysfunction. [from MeSH]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVNeurologic Manifestations

Professional guidelines

PubMed

Koch RL, Soler-Alfonso C, Kiely BT, Asai A, Smith AL, Bali DS, Kang PB, Landstrom AP, Akman HO, Burrow TA, Orthmann-Murphy JL, Goldman DS, Pendyal S, El-Gharbawy AH, Austin SL, Case LE, Schiffmann R, Hirano M, Kishnani PS
Mol Genet Metab 2023 Mar;138(3):107525. Epub 2023 Jan 25 doi: 10.1016/j.ymgme.2023.107525. PMID: 36796138
Sciascia S, Amigo MC, Roccatello D, Khamashta M
Nat Rev Rheumatol 2017 Sep;13(9):548-560. Epub 2017 Aug 3 doi: 10.1038/nrrheum.2017.124. PMID: 28769114
Perry PJ, Wilborn CA
Ann Clin Psychiatry 2012 May;24(2):155-62. PMID: 22563571

Recent clinical studies

Etiology

Leal Rato M, Bandeira M, Romão VC, Aguiar de Sousa D
Curr Neurol Neurosci Rep 2021 Jun 14;21(8):41. doi: 10.1007/s11910-021-01124-z. PMID: 34125304Free PMC Article
Mao L, Jin H, Wang M, Hu Y, Chen S, He Q, Chang J, Hong C, Zhou Y, Wang D, Miao X, Li Y, Hu B
JAMA Neurol 2020 Jun 1;77(6):683-690. doi: 10.1001/jamaneurol.2020.1127. PMID: 32275288Free PMC Article
Serin HM, Arslan EA
Acta Clin Croat 2019 Jun;58(2):295-302. doi: 10.20471/acc.2019.58.02.13. PMID: 31819326Free PMC Article
Islam MP
Handb Clin Neurol 2015;132:111-7. doi: 10.1016/B978-0-444-62702-5.00007-X. PMID: 26564074
Reynolds EH
Handb Clin Neurol 2014;120:927-43. doi: 10.1016/B978-0-7020-4087-0.00061-9. PMID: 24365361

Diagnosis

Mao L, Jin H, Wang M, Hu Y, Chen S, He Q, Chang J, Hong C, Zhou Y, Wang D, Miao X, Li Y, Hu B
JAMA Neurol 2020 Jun 1;77(6):683-690. doi: 10.1001/jamaneurol.2020.1127. PMID: 32275288Free PMC Article
Weisman MH
Rheum Dis Clin North Am 2017 Nov;43(4):xi. doi: 10.1016/j.rdc.2017.08.002. PMID: 29061249
DeQuattro K, Imboden JB
Rheum Dis Clin North Am 2017 Nov;43(4):561-571. Epub 2017 Aug 31 doi: 10.1016/j.rdc.2017.06.005. PMID: 29061242
Margaretten M
Rheum Dis Clin North Am 2017 Nov;43(4):519-529. Epub 2017 Aug 23 doi: 10.1016/j.rdc.2017.06.002. PMID: 29061239
Krumholz A, Stern BJ
Handb Clin Neurol 2014;119:305-33. doi: 10.1016/B978-0-7020-4086-3.00021-7. PMID: 24365304

Therapy

Diesing TS
Continuum (Minneap Minn) 2023 Jun 1;29(3):708-733. doi: 10.1212/CON.0000000000001235. PMID: 37341328
Romeo AR, Segal BM
Curr Opin Rheumatol 2019 May;31(3):250-255. doi: 10.1097/BOR.0000000000000603. PMID: 30920972
Ishii M
Continuum (Minneap Minn) 2017 Jun;23(3, Neurology of Systemic Disease):778-801. doi: 10.1212/CON.0000000000000467. PMID: 28570329Free PMC Article
Kumar N
Neurol Clin 2010 Feb;28(1):107-70. doi: 10.1016/j.ncl.2009.09.006. PMID: 19932379
James DG, Sharma OP
Proc R Soc Med 1967 Nov 1;60(11 Part 1):1169-70. PMID: 6060718Free PMC Article

Prognosis

Cooper D, Suau S
Immunol Allergy Clin North Am 2023 Aug;43(3):583-591. doi: 10.1016/j.iac.2022.10.011. PMID: 37394261
Cooper D, Suau S
Emerg Med Clin North Am 2022 Feb;40(1):149-157. Epub 2021 Oct 29 doi: 10.1016/j.emc.2021.08.012. PMID: 34782085
de Boysson H, Guillevin L
Neurol Clin 2019 May;37(2):345-357. Epub 2019 Mar 16 doi: 10.1016/j.ncl.2019.01.007. PMID: 30952413
Halperin JJ
Neurol Clin 2018 Nov;36(4):821-830. doi: 10.1016/j.ncl.2018.06.006. PMID: 30366557
Micol R, Ben Slama L, Suarez F, Le Mignot L, Beauté J, Mahlaoui N, Dubois d'Enghien C, Laugé A, Hall J, Couturier J, Vallée L, Delobel B, Rivier F, Nguyen K, Billette de Villemeur T, Stephan JL, Bordigoni P, Bertrand Y, Aladjidi N, Pedespan JM, Thomas C, Pellier I, Koenig M, Hermine O, Picard C, Moshous D, Neven B, Lanternier F, Blanche S, Tardieu M, Debré M, Fischer A, Stoppa-Lyonnet D; CEREDIH Network Investigators
J Allergy Clin Immunol 2011 Aug;128(2):382-9.e1. Epub 2011 Jun 12 doi: 10.1016/j.jaci.2011.03.052. PMID: 21665257

Clinical prediction guides

Kısaarslan AP, Çiçek SÖ, Batu ED, Şahin S, Gürgöze MK, Çetinkaya SB, Ekinci MK, Atmış B, Barut K, Adrovic A, Ağar BE, Şahin N, Demir F, Bağlan E, Kara MA, Selçuk ŞZ, Özdel S, Çomak E, Akkoyunlu B, Yener GO, Yıldırım DG, Öztürk K, Yıldız M, Haşlak F, Şener S, Kısaoğlu H, Baba Ö, Kızıldağ Z, İşgüder R, Çağlayan Ş, Bilgin RBG, Aytaç G, Yücel BB, Tanatar A, Sönmez HE, Çakan M, Kara A, Elmas AT, Kılıç BD, Ayaz NA, Kasap B, Acar BÇ, Ozkaya O, Yüksel S, Bakkaloğlu S, Aydoğ Ö, Aksu G, Akman S, Dönmez O, Bülbül M, Büyükçelik M, Tabel Y, Sözeri B, Kalyoncu M, Bilginer Y, Poyrazoğlu MH, Ünsal E, Kasapçopur Ö, Özen S, Düşünsel R
Joint Bone Spine 2023 Jul;90(4):105559. Epub 2023 Feb 28 doi: 10.1016/j.jbspin.2023.105559. PMID: 36858168
Grant SJ, Grimshaw AA, Silberstein J, Murdaugh D, Wildes TM, Rosko AE, Giri S
Transplant Cell Ther 2022 Jun;28(6):294-302. Epub 2022 Mar 11 doi: 10.1016/j.jtct.2022.03.006. PMID: 35288347Free PMC Article
Mao L, Jin H, Wang M, Hu Y, Chen S, He Q, Chang J, Hong C, Zhou Y, Wang D, Miao X, Li Y, Hu B
JAMA Neurol 2020 Jun 1;77(6):683-690. doi: 10.1001/jamaneurol.2020.1127. PMID: 32275288Free PMC Article
Fousekis FS, Mitselos IV, Christodoulou DK
Clin Mol Hepatol 2020 Jan;26(1):16-23. Epub 2019 Oct 11 doi: 10.3350/cmh.2019.0082. PMID: 31601068Free PMC Article
Halperin JJ
Neurol Clin 2018 Nov;36(4):821-830. doi: 10.1016/j.ncl.2018.06.006. PMID: 30366557

Recent systematic reviews

Grant SJ, Grimshaw AA, Silberstein J, Murdaugh D, Wildes TM, Rosko AE, Giri S
Transplant Cell Ther 2022 Jun;28(6):294-302. Epub 2022 Mar 11 doi: 10.1016/j.jtct.2022.03.006. PMID: 35288347Free PMC Article
Miranda GHN, Alvarenga MOP, Ferreira MKM, Puty B, Bittencourt LO, Fagundes NCF, Pessan JP, Buzalaf MAR, Lima RR
Sci Rep 2021 Nov 22;11(1):22659. doi: 10.1038/s41598-021-99688-w. PMID: 34811523Free PMC Article
Misra S, Kolappa K, Prasad M, Radhakrishnan D, Thakur KT, Solomon T, Michael BD, Winkler AS, Beghi E, Guekht A, Pardo CA, Wood GK, Hsiang-Yi Chou S, Fink EL, Schmutzhard E, Kheradmand A, Hoo FK, Kumar A, Das A, Srivastava AK, Agarwal A, Dua T, Prasad K
Neurology 2021 Dec 7;97(23):e2269-e2281. Epub 2021 Oct 11 doi: 10.1212/WNL.0000000000012930. PMID: 34635561Free PMC Article
Collantes MEV, Espiritu AI, Sy MCC, Anlacan VMM, Jamora RDG
Can J Neurol Sci 2021 Jan;48(1):66-76. Epub 2020 Jul 15 doi: 10.1017/cjn.2020.146. PMID: 32665054Free PMC Article
Touzé E, Southerland AM, Boulanger M, Labeyrie PE, Azizi M, Bouatia-Naji N, Debette S, Gornik HL, Hussain SM, Jeunemaitre X, Joux J, Kirton A, Le Hello C, Majersik JJ, Mocco J, Persu A, Sharma A, Worrall BB, Olin JW, Plouin PF
JAMA Neurol 2019 Feb 1;76(2):217-226. doi: 10.1001/jamaneurol.2018.2848. PMID: 30285053

Supplemental Content

Table of contents

    Practice guidelines

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      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

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