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Neoplasm of the male external genitalia

MedGen UID:
866604
•Concept ID:
C4020950
•
Neoplastic Process
Synonym: Neoplasia of the male external genitalia
 
HPO: HP:0100848

Definition

A tumor (abnormal growth of tissue) of the male external genitalia. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVNeoplasm of the male external genitalia

Professional guidelines

PubMed

The role of radiotherapy in the management of squamous cell cancer of the penis.
Crook J
World J Urol 2023 Dec;41(12):3913-3920. Epub 2023 Nov 23 doi: 10.1007/s00345-023-04683-7. PMID: 37994970
Unresolved issues in the management of human papillomavirus-associated mucosal high-grade pre-cancers.
Lacey CJ
Tumour Virus Res 2023 Jun;15:200250. Epub 2023 Jan 20 doi: 10.1016/j.tvr.2022.200250. PMID: 36682539Free PMC Article
Extramammary Paget's Disease: Diagnosis, Pathogenesis, and Treatment with Focus on Recent Developments.
Ishizuki S, Nakamura Y
Curr Oncol 2021 Aug 5;28(4):2969-2986. doi: 10.3390/curroncol28040260. PMID: 34436026Free PMC Article

Recent clinical studies

Etiology

Human Papilloma Virus-Infected Cells.
Cruz-Gregorio A, Aranda-Rivera AK
Subcell Biochem 2023;106:213-226. doi: 10.1007/978-3-031-40086-5_8. PMID: 38159229
Epidemiology, Risk Factors, and Prevention of Head and Neck Squamous Cell Carcinoma.
Barsouk A, Aluru JS, Rawla P, Saginala K, Barsouk A
Med Sci (Basel) 2023 Jun 13;11(2) doi: 10.3390/medsci11020042. PMID: 37367741Free PMC Article
Epidemiology and burden of HPV-related disease.
Serrano B, Brotons M, Bosch FX, Bruni L
Best Pract Res Clin Obstet Gynaecol 2018 Feb;47:14-26. Epub 2017 Sep 2 doi: 10.1016/j.bpobgyn.2017.08.006. PMID: 29037457
Cutaneous Squamous Cell Carcinoma: A Review of High-Risk and Metastatic Disease.
Burton KA, Ashack KA, Khachemoune A
Am J Clin Dermatol 2016 Oct;17(5):491-508. doi: 10.1007/s40257-016-0207-3. PMID: 27358187
Bowenoid papulosis.
Rogozinski TT, Janniger CK
Am Fam Physician 1988 Jul;38(1):161-4. PMID: 2839970

Diagnosis

Epidemiology, Risk Factors, and Prevention of Head and Neck Squamous Cell Carcinoma.
Barsouk A, Aluru JS, Rawla P, Saginala K, Barsouk A
Med Sci (Basel) 2023 Jun 13;11(2) doi: 10.3390/medsci11020042. PMID: 37367741Free PMC Article
Papillomaviruses and cancer: commonalities and differences in HPV carcinogenesis at different sites of the body.
Egawa N
Int J Clin Oncol 2023 Aug;28(8):956-964. Epub 2023 May 18 doi: 10.1007/s10147-023-02340-y. PMID: 37199886Free PMC Article
Extramammary Paget's Disease: Diagnosis, Pathogenesis, and Treatment with Focus on Recent Developments.
Ishizuki S, Nakamura Y
Curr Oncol 2021 Aug 5;28(4):2969-2986. doi: 10.3390/curroncol28040260. PMID: 34436026Free PMC Article
Extramammary Paget disease.
St Claire K, Hoover A, Ashack K, Khachemoune A
Dermatol Online J 2019 Apr 15;25(4) PMID: 31046904
Cutaneous Squamous Cell Carcinoma: A Review of High-Risk and Metastatic Disease.
Burton KA, Ashack KA, Khachemoune A
Am J Clin Dermatol 2016 Oct;17(5):491-508. doi: 10.1007/s40257-016-0207-3. PMID: 27358187

Therapy

Vaccines for HPV-associated diseases.
Skolnik JM, Morrow MP
Mol Aspects Med 2023 Dec;94:101224. Epub 2023 Nov 4 doi: 10.1016/j.mam.2023.101224. PMID: 37931422
Editor's picks.
J Eur Acad Dermatol Venereol 2020 Apr;34(4):665. doi: 10.1111/jdv.16353. PMID: 32227421
Long-Term Follow-Up after Treatment of Cryptorchidism.
Thorup J, Cortes D
Eur J Pediatr Surg 2016 Oct;26(5):427-431. Epub 2016 Sep 2 doi: 10.1055/s-0036-1592138. PMID: 27589079
Malignancy.
Penn I
Surg Clin North Am 1994 Oct;74(5):1247-57. PMID: 7940072
Ambiguous external genitalia in the newborn and prepubescent child.
Dmowski WP, Greenblatt RB
JAMA 1970 Apr 13;212(2):308-11. PMID: 5467232

Prognosis

Extramammary Paget's Disease: Diagnosis, Pathogenesis, and Treatment with Focus on Recent Developments.
Ishizuki S, Nakamura Y
Curr Oncol 2021 Aug 5;28(4):2969-2986. doi: 10.3390/curroncol28040260. PMID: 34436026Free PMC Article
Extramammary Paget disease.
St Claire K, Hoover A, Ashack K, Khachemoune A
Dermatol Online J 2019 Apr 15;25(4) PMID: 31046904
Epidemiology and burden of HPV-related disease.
Serrano B, Brotons M, Bosch FX, Bruni L
Best Pract Res Clin Obstet Gynaecol 2018 Feb;47:14-26. Epub 2017 Sep 2 doi: 10.1016/j.bpobgyn.2017.08.006. PMID: 29037457
Cutaneous Squamous Cell Carcinoma: A Review of High-Risk and Metastatic Disease.
Burton KA, Ashack KA, Khachemoune A
Am J Clin Dermatol 2016 Oct;17(5):491-508. doi: 10.1007/s40257-016-0207-3. PMID: 27358187
Global burden of human papillomavirus and related diseases.
Forman D, de Martel C, Lacey CJ, Soerjomataram I, Lortet-Tieulent J, Bruni L, Vignat J, Ferlay J, Bray F, Plummer M, Franceschi S
Vaccine 2012 Nov 20;30 Suppl 5:F12-23. doi: 10.1016/j.vaccine.2012.07.055. PMID: 23199955

Clinical prediction guides

Papillomaviruses and cancer: commonalities and differences in HPV carcinogenesis at different sites of the body.
Egawa N
Int J Clin Oncol 2023 Aug;28(8):956-964. Epub 2023 May 18 doi: 10.1007/s10147-023-02340-y. PMID: 37199886Free PMC Article
Extramammary Paget Disease.
Marcoval J, Penín RM, Vidal A, Bermejo J
Actas Dermosifiliogr (Engl Ed) 2020 May;111(4):306-312. Epub 2020 Apr 9 doi: 10.1016/j.ad.2019.09.003. PMID: 32278442
Extramammary Paget disease.
St Claire K, Hoover A, Ashack K, Khachemoune A
Dermatol Online J 2019 Apr 15;25(4) PMID: 31046904
Cutaneous Squamous Cell Carcinoma: A Review of High-Risk and Metastatic Disease.
Burton KA, Ashack KA, Khachemoune A
Am J Clin Dermatol 2016 Oct;17(5):491-508. doi: 10.1007/s40257-016-0207-3. PMID: 27358187
PELVIS Syndrome.
Girard C, Bigorre M, Guillot B, Bessis D
Arch Dermatol 2006 Jul;142(7):884-8. doi: 10.1001/archderm.142.7.884. PMID: 16847205

Recent systematic reviews

Side-chain cleavage enzyme deficiency: Systematic review and case series.
Phadte A, Arya S, Sarathi V, Lila A, Maheshwari M, Memon SS, Rane A, Patil V, Rai K, Raghav D, Kunwar A, Bandgar T
Clin Endocrinol (Oxf) 2023 Mar;98(3):351-362. Epub 2022 Nov 17 doi: 10.1111/cen.14848. PMID: 36357326
Real-world impact and effectiveness assessment of the quadrivalent HPV vaccine: a systematic review of study designs and data sources.
Wang W, Kothari S, Baay M, Garland SM, Giuliano AR, Nygård M, Velicer C, Tota J, Sinha A, Skufca J, Verstraeten T, Sundström K
Expert Rev Vaccines 2022 Feb;21(2):227-240. Epub 2021 Dec 13 doi: 10.1080/14760584.2022.2008243. PMID: 34845951
Anogenital warts and relationship to child sexual abuse: Systematic review and meta-analysis.
Awasthi S, Ornelas J, Armstrong A, Johnson JA, Eisen DB
Pediatr Dermatol 2021 Jul;38(4):842-850. Epub 2021 Jun 1 doi: 10.1111/pde.14650. PMID: 34060139
Granular cell tumor a study of 42 cases and systemic review of the literature.
Mobarki M, Dumollard JM, Dal Col P, Camy F, Peoc'h M, Karpathiou G
Pathol Res Pract 2020 Apr;216(4):152865. Epub 2020 Feb 12 doi: 10.1016/j.prp.2020.152865. PMID: 32089415
Pregnancy and genital sarcoma: a systematic review of the literature.
Matsuo K, Eno ML, Im DD, Rosenshein NB
Am J Perinatol 2009 Aug;26(7):507-18. Epub 2009 Mar 13 doi: 10.1055/s-0029-1215428. PMID: 19288396

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