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Neonatal disorder

MedGen UID:
9460
•Concept ID:
C0021290
•
Disease or Syndrome
Synonyms: Disease, Neonatal; Diseases, Neonatal; Infant, Newborn, Diseases; Neonatal Disease; Neonatal Diseases
SNOMED CT: Neonatal disorder (22925008); Neonatal disease (22925008)

Definition

A non-neoplastic or neoplastic disorder which occurs during the neonatal period. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVNeonatal disorder

Professional guidelines

PubMed

The Assessment and Management of Biliary Atresia in Hawai'i, 2009-2023.
Singh SA, Balaraman KK, Johnson MI, Balaraman V, Puapong DP, Johnson SM, Tabak BD, Woo RK
Hawaii J Health Soc Welf 2024 Oct;83(10):268-273. doi: 10.62547/NUOX8943. PMID: 39371585Free PMC Article
Clinical Pharmacogenetics Implementation Consortium Guideline for CYP2B6 Genotype and Methadone Therapy.
Robinson KM, Eum S, Desta Z, Tyndale RF, Gaedigk A, Crist RC, Haidar CE, Myers AL, Samer CF, Somogyi AA, Zubiaur P, Iwuchukwu OF, Whirl-Carrillo M, Klein TE, Caudle KE, Donnelly RS, Kharasch ED
Clin Pharmacol Ther 2024 Oct;116(4):932-938. Epub 2024 Jun 11 doi: 10.1002/cpt.3338. PMID: 38863207Free PMC Article
Phelan McDermid Syndrome: From Genetic Discoveries to Animal Models and Treatment.
Harony-Nicolas H, De Rubeis S, Kolevzon A, Buxbaum JD
J Child Neurol 2015 Dec;30(14):1861-70. Epub 2015 Sep 8 doi: 10.1177/0883073815600872. PMID: 26350728Free PMC Article

Recent clinical studies

Etiology

The Assessment and Management of Biliary Atresia in Hawai'i, 2009-2023.
Singh SA, Balaraman KK, Johnson MI, Balaraman V, Puapong DP, Johnson SM, Tabak BD, Woo RK
Hawaii J Health Soc Welf 2024 Oct;83(10):268-273. doi: 10.62547/NUOX8943. PMID: 39371585Free PMC Article
Neonatal sepsis as a cause of retinopathy of prematurity: An etiological explanation.
Dammann O, Stansfield BK
Prog Retin Eye Res 2024 Jan;98:101230. Epub 2023 Nov 19 doi: 10.1016/j.preteyeres.2023.101230. PMID: 37984792Free PMC Article
Nicotinamide nucleotide transhydrogenase mutation analysis in Chinese patients with thyroid dysgenesis.
Li M, Tian W, Wang F, Yang C, Zhang L, Tang Q, Liu S, Wang F
Am J Med Genet A 2022 Jan;188(1):89-98. Epub 2021 Sep 21 doi: 10.1002/ajmg.a.62493. PMID: 34545694
The use of IVIg in fetal and neonatal alloimmune thrombocytopenia- Principles and mechanisms.
Wabnitz H, Khan R, Lazarus AH
Transfus Apher Sci 2020 Feb;59(1):102710. Epub 2019 Dec 31 doi: 10.1016/j.transci.2019.102710. PMID: 31926738
Congenital hypothyroidism: an analysis of persisting deficits and associated factors.
Rovet JF
Child Neuropsychol 2002 Sep;8(3):150-62. doi: 10.1076/chin.8.3.150.13501. PMID: 12759831

Diagnosis

The Assessment and Management of Biliary Atresia in Hawai'i, 2009-2023.
Singh SA, Balaraman KK, Johnson MI, Balaraman V, Puapong DP, Johnson SM, Tabak BD, Woo RK
Hawaii J Health Soc Welf 2024 Oct;83(10):268-273. doi: 10.62547/NUOX8943. PMID: 39371585Free PMC Article
Temporal Trends of Neonatal Surgical Conditions in Texas and Accessibility to Pediatric Surgical Care.
Shah NR, Price A, Mobli K, O'Leary S, Radhakrishnan RS
J Surg Res 2024 Apr;296:29-36. Epub 2024 Jan 11 doi: 10.1016/j.jss.2023.12.009. PMID: 38215674
Disseminated intravascular coagulation complicated by amniotic band syndrome associated with deceased fetal umbilical cord following fetoscopic laser surgery.
Ogoyama M, Takahashi H, Kagawa K, Shimozawa H, Yada Y, Wada S, Sago H, Fujiwara H
J Obstet Gynaecol Res 2022 Jul;48(7):1989-1996. Epub 2022 May 25 doi: 10.1111/jog.15281. PMID: 35614528
Stem Cell Based Models in Congenital Hyperinsulinism - Perspective on Practicalities and Possibilities.
Lithovius V, Otonkoski T
Front Endocrinol (Lausanne) 2022;13:837450. Epub 2022 Feb 18 doi: 10.3389/fendo.2022.837450. PMID: 35250887Free PMC Article
Congenital hypothyroidism: an analysis of persisting deficits and associated factors.
Rovet JF
Child Neuropsychol 2002 Sep;8(3):150-62. doi: 10.1076/chin.8.3.150.13501. PMID: 12759831

Therapy

Disseminated intravascular coagulation complicated by amniotic band syndrome associated with deceased fetal umbilical cord following fetoscopic laser surgery.
Ogoyama M, Takahashi H, Kagawa K, Shimozawa H, Yada Y, Wada S, Sago H, Fujiwara H
J Obstet Gynaecol Res 2022 Jul;48(7):1989-1996. Epub 2022 May 25 doi: 10.1111/jog.15281. PMID: 35614528
The use of IVIg in fetal and neonatal alloimmune thrombocytopenia- Principles and mechanisms.
Wabnitz H, Khan R, Lazarus AH
Transfus Apher Sci 2020 Feb;59(1):102710. Epub 2019 Dec 31 doi: 10.1016/j.transci.2019.102710. PMID: 31926738
Brain malformations associated to Aldh7a1 gene mutations: Report of a novel homozygous mutation and literature review.
Toldo I, Bonardi CM, Bettella E, Polli R, Talenti G, Burlina A, Sartori S, Murgia A
Eur J Paediatr Neurol 2018 Nov;22(6):1042-1053. Epub 2018 Jul 3 doi: 10.1016/j.ejpn.2018.06.010. PMID: 30005813
Sclerema neonatorum treated with intravenous immunoglobulin: a case report and review of treatments.
Buster KJ, Burford HN, Stewart FA, Sellheyer K, Hughey LC
Cutis 2013 Aug;92(2):83-7. PMID: 24087781
Genotypic and phenotypic spectrum of pyridoxine-dependent epilepsy (ALDH7A1 deficiency).
Mills PB, Footitt EJ, Mills KA, Tuschl K, Aylett S, Varadkar S, Hemingway C, Marlow N, Rennie J, Baxter P, Dulac O, Nabbout R, Craigen WJ, Schmitt B, Feillet F, Christensen E, De Lonlay P, Pike MG, Hughes MI, Struys EA, Jakobs C, Zuberi SM, Clayton PT
Brain 2010 Jul;133(Pt 7):2148-59. Epub 2010 Jun 16 doi: 10.1093/brain/awq143. PMID: 20554659Free PMC Article

Prognosis

Global burden and inequality of maternal and neonatal disorders: based on data from the 2019 Global Burden of Disease study.
Peng R, Tong Y, Yang M, Wang J, Yang L, Zhu J, Liu Y, Wang H, Shi Z, Liu Y
QJM 2024 Feb 7;117(1):24-37. doi: 10.1093/qjmed/hcad220. PMID: 37773990Free PMC Article
Global trends in incidence and death of neonatal disorders and its specific causes in 204 countries/territories during 1990-2019.
Ou Z, Yu D, Liang Y, He H, He W, Li Y, Zhang M, Gao Y, Wu F, Chen Q
BMC Public Health 2022 Feb 19;22(1):360. doi: 10.1186/s12889-022-12765-1. PMID: 35183143Free PMC Article
Thrombocytopenia in late preterm and term neonates after perinatal asphyxia.
Christensen RD, Baer VL, Yaish HM
Transfusion 2015 Jan;55(1):187-96. Epub 2014 Aug 1 doi: 10.1111/trf.12777. PMID: 25082082
Sclerema neonatorum treated with intravenous immunoglobulin: a case report and review of treatments.
Buster KJ, Burford HN, Stewart FA, Sellheyer K, Hughey LC
Cutis 2013 Aug;92(2):83-7. PMID: 24087781
A review of evidence for a role of magnesium and possibly copper deficiency in necrotizing enterocolitis.
Caddell JL
Magnes Res 1996 Mar;9(1):55-66. PMID: 8819095

Clinical prediction guides

Global trends in incidence and death of neonatal disorders and its specific causes in 204 countries/territories during 1990-2019.
Ou Z, Yu D, Liang Y, He H, He W, Li Y, Zhang M, Gao Y, Wu F, Chen Q
BMC Public Health 2022 Feb 19;22(1):360. doi: 10.1186/s12889-022-12765-1. PMID: 35183143Free PMC Article
An immunohistochemical study of placental syncytiotrophoblasts in neonatal hemochromatosis.
Shimono A, Imoto Y, Sakamoto H, Chiba Y, Matsumoto K, Kawauchi M, Kusaka T, Tanaka H, Hata T, Kushida Y, Ueno M
Placenta 2016 Dec;48:49-55. Epub 2016 Oct 12 doi: 10.1016/j.placenta.2016.10.005. PMID: 27871472
Infantile seborrheic dermatitis: a pediatric Siddha medicine treatise.
Thambyayah M, Amuthan A
Clin Dermatol 2015 May-Jun;33(3):355-61. Epub 2014 Dec 8 doi: 10.1016/j.clindermatol.2014.12.013. PMID: 25889138
Exome sequencing identifies mutations in the gene TTC7A in French-Canadian cases with hereditary multiple intestinal atresia.
Samuels ME, Majewski J, Alirezaie N, Fernandez I, Casals F, Patey N, Decaluwe H, Gosselin I, Haddad E, Hodgkinson A, Idaghdour Y, Marchand V, Michaud JL, Rodrigue MA, Desjardins S, Dubois S, Le Deist F, Awadalla P, Raymond V, Maranda B
J Med Genet 2013 May;50(5):324-9. Epub 2013 Feb 19 doi: 10.1136/jmedgenet-2012-101483. PMID: 23423984Free PMC Article
Congenital hypothyroidism: an analysis of persisting deficits and associated factors.
Rovet JF
Child Neuropsychol 2002 Sep;8(3):150-62. doi: 10.1076/chin.8.3.150.13501. PMID: 12759831

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