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Liver Epithelial Neoplasm

MedGen UID:
272578
Concept ID:
C1333419
Neoplastic Process
Synonyms: Epithelial Hepatic and Intrahepatic Bile Duct Neoplasm; Liver and Intrahepatic Bile Duct Epithelial Neoplasm

Definition

A benign or malignant epithelial neoplasm that affects the liver. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVLiver Epithelial Neoplasm

Professional guidelines

PubMed

Vogel A, Cervantes A, Chau I, Daniele B, Llovet JM, Meyer T, Nault JC, Neumann U, Ricke J, Sangro B, Schirmacher P, Verslype C, Zech CJ, Arnold D, Martinelli E; ESMO Guidelines Committee
Ann Oncol 2018 Oct 1;29(Suppl 4):iv238-iv255. doi: 10.1093/annonc/mdy308. PMID: 30285213
European Association for the Study of the Liver
J Hepatol 2018 Jul;69(1):182-236. Epub 2018 Apr 5 doi: 10.1016/j.jhep.2018.03.019. PMID: 29628281
European Association for the Study of the Liver
J Hepatol 2017 Aug;67(2):370-398. Epub 2017 Apr 18 doi: 10.1016/j.jhep.2017.03.021. PMID: 28427875

Recent clinical studies

Etiology

Villanueva A
N Engl J Med 2019 Apr 11;380(15):1450-1462. doi: 10.1056/NEJMra1713263. PMID: 30970190
Gupta M, Gabriel H, Miller FH
Gastroenterol Clin North Am 2018 Sep;47(3):585-602. Epub 2018 Jul 7 doi: 10.1016/j.gtc.2018.04.013. PMID: 30115439
Razumilava N, Gores GJ
Lancet 2014 Jun 21;383(9935):2168-79. Epub 2014 Feb 26 doi: 10.1016/S0140-6736(13)61903-0. PMID: 24581682Free PMC Article
El-Serag HB
N Engl J Med 2011 Sep 22;365(12):1118-27. doi: 10.1056/NEJMra1001683. PMID: 21992124
Schuppan D, Afdhal NH
Lancet 2008 Mar 8;371(9615):838-51. doi: 10.1016/S0140-6736(08)60383-9. PMID: 18328931Free PMC Article

Diagnosis

Giraud J, Chalopin D, Blanc JF, Saleh M
Front Immunol 2021;12:655697. Epub 2021 Mar 18 doi: 10.3389/fimmu.2021.655697. PMID: 33815418Free PMC Article
Akkoç Y, Gözüaçık D
Turk J Gastroenterol 2018 May;29(3):270-282. doi: 10.5152/tjg.2018.150318. PMID: 29755011Free PMC Article
Ayuso C, Rimola J, Vilana R, Burrel M, Darnell A, García-Criado Á, Bianchi L, Belmonte E, Caparroz C, Barrufet M, Bruix J, Brú C
Eur J Radiol 2018 Apr;101:72-81. Epub 2018 Jan 31 doi: 10.1016/j.ejrad.2018.01.025. PMID: 29571804
Razumilava N, Gores GJ
Lancet 2014 Jun 21;383(9935):2168-79. Epub 2014 Feb 26 doi: 10.1016/S0140-6736(13)61903-0. PMID: 24581682Free PMC Article
Schuppan D, Afdhal NH
Lancet 2008 Mar 8;371(9615):838-51. doi: 10.1016/S0140-6736(08)60383-9. PMID: 18328931Free PMC Article

Therapy

Simon TG, Wilechansky RM, Stoyanova S, Grossman A, Dichtel LE, Lauer GM, Miller KK, Hoshida Y, Corey KE, Loomba R, Chung RT, Chan AT
JAMA 2024 Mar 19;331(11):920-929. doi: 10.1001/jama.2024.1215. PMID: 38502074Free PMC Article
Xing R, Gao J, Cui Q, Wang Q
Front Immunol 2021;12:783236. Epub 2021 Nov 26 doi: 10.3389/fimmu.2021.783236. PMID: 34899747Free PMC Article
Oura K, Morishita A, Tani J, Masaki T
Int J Mol Sci 2021 May 28;22(11) doi: 10.3390/ijms22115801. PMID: 34071550Free PMC Article
Ielasi L, Tovoli F, Piscaglia F
Drugs Today (Barc) 2019 May;55(5):305-313. doi: 10.1358/dot.2019.55.5.2969817. PMID: 31131841
Villanueva A
N Engl J Med 2019 Apr 11;380(15):1450-1462. doi: 10.1056/NEJMra1713263. PMID: 30970190

Prognosis

Tripathi PR, Sen Sarma M, Srivastava A
Dig Liver Dis 2022 Feb;54(2):282. Epub 2020 Oct 26 doi: 10.1016/j.dld.2020.10.004. PMID: 33115626
Khan SA, Tavolari S, Brandi G
Liver Int 2019 May;39 Suppl 1:19-31. Epub 2019 Mar 24 doi: 10.1111/liv.14095. PMID: 30851228
Ilyas SI, Gores GJ
Gastroenterology 2013 Dec;145(6):1215-29. Epub 2013 Oct 15 doi: 10.1053/j.gastro.2013.10.013. PMID: 24140396Free PMC Article
Poultsides GA, Zhu AX, Choti MA, Pawlik TM
Surg Clin North Am 2010 Aug;90(4):817-37. doi: 10.1016/j.suc.2010.04.011. PMID: 20637950
Blechacz BR, Gores GJ
Clin Liver Dis 2008 Feb;12(1):131-50, ix. doi: 10.1016/j.cld.2007.11.003. PMID: 18242501

Clinical prediction guides

Gan X, Dong W, You W, Ding D, Yang Y, Sun D, Li W, Ding W, Liang Y, Yang F, Zhou W, Dong H, Yuan S
Cancer Lett 2024 Jan 28;581:216513. Epub 2023 Nov 28 doi: 10.1016/j.canlet.2023.216513. PMID: 38036041
Bianco C, Jamialahmadi O, Pelusi S, Baselli G, Dongiovanni P, Zanoni I, Santoro L, Maier S, Liguori A, Meroni M, Borroni V, D'Ambrosio R, Spagnuolo R, Alisi A, Federico A, Bugianesi E, Petta S, Miele L, Vespasiani-Gentilucci U, Anstee QM, Stickel F, Hampe J, Fischer J, Berg T, Fracanzani AL, Soardo G, Reeves H, Prati D, Romeo S, Valenti L
J Hepatol 2021 Apr;74(4):775-782. Epub 2020 Nov 25 doi: 10.1016/j.jhep.2020.11.024. PMID: 33248170Free PMC Article
Ponnatapura J, Kielar A, Burke LMB, Lockhart ME, Abualruz AR, Tappouni R, Lalwani N
Magn Reson Imaging 2019 Jul;60:110-121. Epub 2019 Apr 19 doi: 10.1016/j.mri.2019.04.010. PMID: 31009688
Takahashi Y, Fukusato T
World J Gastroenterol 2014 Nov 14;20(42):15539-48. doi: 10.3748/wjg.v20.i42.15539. PMID: 25400438Free PMC Article
Victor DW, Sherman S, Karakan T, Khashab MA
World J Gastroenterol 2012 Nov 21;18(43):6197-205. doi: 10.3748/wjg.v18.i43.6197. PMID: 23180939Free PMC Article

Recent systematic reviews

Liu R, Qiu Z, Zhang L, Ma W, Zi L, Wang K, Kuang T, Zhao K, Wang W
J Cachexia Sarcopenia Muscle 2023 Dec;14(6):2509-2519. Epub 2023 Nov 22 doi: 10.1002/jcsm.13371. PMID: 37990969Free PMC Article
Ding ZN, Meng GX, Xue JS, Liu H, Yang LS, Li RZ, Mao XC, Yan YC, Wang DX, Dong ZR, Li T
Crit Rev Oncol Hematol 2023 Apr;184:103940. Epub 2023 Feb 15 doi: 10.1016/j.critrevonc.2023.103940. PMID: 36805079
Tan DJH, Ng CH, Lin SY, Pan XH, Tay P, Lim WH, Teng M, Syn N, Lim G, Yong JN, Quek J, Xiao J, Dan YY, Siddiqui MS, Sanyal AJ, Muthiah MD, Loomba R, Huang DQ
Lancet Oncol 2022 Apr;23(4):521-530. Epub 2022 Mar 4 doi: 10.1016/S1470-2045(22)00078-X. PMID: 35255263Free PMC Article
Harding-Theobald E, Louissaint J, Maraj B, Cuaresma E, Townsend W, Mendiratta-Lala M, Singal AG, Su GL, Lok AS, Parikh ND
Aliment Pharmacol Ther 2021 Oct;54(7):890-901. Epub 2021 Aug 12 doi: 10.1111/apt.16563. PMID: 34390014Free PMC Article
Clements O, Eliahoo J, Kim JU, Taylor-Robinson SD, Khan SA
J Hepatol 2020 Jan;72(1):95-103. Epub 2019 Sep 16 doi: 10.1016/j.jhep.2019.09.007. PMID: 31536748

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